{"title":"Fluorinated Building Blocks","description":"\u003cp\u003e\u003cstrong\u003eFluorinated Building Blocks\u003c\/strong\u003e — berisi building block yang mengandung gugus fluor atau trifluorometil, baik pada kerangka heterosiklik maupun non-heterosiklik, seperti turunan benzena, sikloheksana, dan senyawa aromatik lain. Kategori ini menyediakan sumber atom fluor untuk memodifikasi sifat elektronik dan lipofilisitas molekul target.\u003c\/p\u003e\u003cp\u003eBuilding block terfluorinasi ini dipakai dalam kimia medisinal dan ilmu material untuk menyisipkan gugus trifluorometil atau fluor yang memengaruhi stabilitas metabolik dan afinitas ikatan pada rancangan molekul. Senyawa seperti turunan bis(trifluorometil) dan nitrobenzena terfluorinasi juga dipakai sebagai zat antara pada sintesis bertahap menuju struktur aromatik kompleks.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510b19497480\"\u003eTCI B1949 30071-93-3 3',5'-Bis(trifluoromethyl)acetophenone\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b555712215\"\u003eTCI B5557 1637638-66-4 2-(tert-Butyldimethylsilyl)-1,3-phenylene Bis(trifluoromethanesulfonate)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b17517170\"\u003eTCI B1751 401-95-6 3,5-Bis(trifluoromethyl)benzaldehyde\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b564512341\"\u003eTCI B5645 79850-12-7 1,3-Bis(trifluoromethyl)cyclohexane (cis- and trans- mixture)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c282117694\"\u003eTCI C2821 129825-11-2 4'-Chloro-3'-(trifluoromethyl)acetophenone\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b564612343\"\u003eTCI B5646 433-18-1 1,4-Bis(trifluoromethyl)cyclohexane (cis- and trans- mixture)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510a0377551\"\u003eTCI A0377 393-11-3 5-Amino-2-nitrobenzotrifluoride\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b568812397\"\u003eTCI B5688 345-24-4 1-Bromo-2,4-difluoro-5-nitrobenzene\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan posisi substitusi fluor pada cincin, ada tidaknya campuran isomer cis\/trans seperti pada turunan sikloheksana difluorinasi, serta kemurnian dan bentuk kemasan yang sesuai. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Building Blocks untuk Sintesis Organik, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-non-heterocyclic-building-blocks\"\u003eNon-Heterocyclic Building Blocks\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-heterocyclic-building-blocks\"\u003eHeterocyclic Building Blocks\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-specialized-building-blocks-for-drug-discovery\"\u003eSpecialized Building Blocks for Drug Discovery\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKoleksi ini masih terbagi menjadi 2 kelompok yang lebih spesifik:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-non-heterocyclic-fluorinated-building-blocks\"\u003eNon-Heterocyclic Fluorinated Building Blocks\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-heterocyclic-fluorinated-building-blocks\"\u003eHeterocyclic Fluorinated Building Blocks\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/building-blocks-sintesis-organik\"\u003eBuilding Blocks untuk Sintesis Organik\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510b568812397","title":"TCI B5688 345-24-4 1-Bromo-2,4-difluoro-5-nitrobenzene","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e1-Bromo-2,4-difluoro-5-nitrobenzene (CAS 345-24-4) is a versatile fluorinated aromatic building block widely employed in organic synthesis for constructing complex molecules via nucleophilic aromatic substitution and cross-coupling reactions. Its unique combination of bromo, difluoro, and nitro substituents on the benzene ring makes it an ideal intermediate for pharmaceutical and agrochemical research, particularly in the development of fluorinated drug candidates with enhanced metabolic stability. This TCI product is available in 1g and 5g packaging options suitable for both exploratory and scale-up laboratory research.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":50506878157018,"sku":"TCI2510B568812397","price":784000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B5688.jpg?v=1768815860"},{"product_id":"tci2510b570512420","title":"TCI B5705 7387-69-1 N-Benzyl-2,2,2-trifluoroacetamide","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eN-Benzyl-2,2,2-trifluoroacetamide (CAS 7387-69-1) is a fluorinated building block from TCI, widely used in organic synthesis to introduce trifluoromethyl groups into target molecular structures. It serves as a valuable precursor in carbon-nitrogen bond formation and amide functional group modification, commonly applied in medicinal chemistry for drug candidate synthesis and bioactive molecule development. This compound is also utilized in agrochemical research and the development of fluorinated materials with distinctive physicochemical properties.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48085898297562,"sku":"TCI2510B570512420","price":1263000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48085898330330,"sku":"TCI2510B570512421","price":4897000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B5705.jpg?v=1768815864"},{"product_id":"tci2510b572212445","title":"TCI B5722 64695-84-7 2-Bromo-4,5-difluorobenzoic Acid","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B5722 2-Bromo-4,5-difluorobenzoic Acid (CAS 64695-84-7) is a fluorinated aromatic building block designed for organic synthesis in research laboratories. This compound serves as a versatile intermediate for constructing complex molecular architectures through cross-coupling and aromatic substitution reactions. It is commonly utilized in medicinal chemistry, agrochemical development, and the synthesis of functional materials where fluorine substitution enhances metabolic stability and thermal performance.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48085899280602,"sku":"TCI2510B572212445","price":1541000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48085899313370,"sku":"TCI2510B572212446","price":5276000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B5722.jpg?v=1769180219"},{"product_id":"tci2510b582812583","title":"TCI B5828 191165-13-6 4-Bromo-2-(trifluoromethyl)benzonitrile","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B5828 4-Bromo-2-(trifluoromethyl)benzonitrile (CAS 191165-13-6) is a fluorinated aromatic building block widely utilized in organic synthesis for medicinal chemistry, agrochemical development, and advanced material research. The compound features both bromo and trifluoromethyl substituents on a benzonitrile scaffold, enabling versatile reactivity in cross-coupling and nucleophilic substitution reactions. Its trifluoromethyl moiety enhances lipophilicity and metabolic stability, making it a valuable intermediate in drug discovery and bioactive molecule design.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48085905539290,"sku":"TCI2510B582812583","price":2399000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48085905572058,"sku":"TCI2510B582812584","price":8355000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B5828.jpg?v=1768815912"},{"product_id":"tci2510b603112832","title":"TCI B6031 204205-33-4 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6031 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone is a high-purity fluorinated building block designed for advanced organic synthesis and medicinal chemistry research. Its reactive bromo group enables versatile coupling and substitution reactions, while the cyclopropyl ring and fluorinated aromatic system contribute desirable rigidity and electronic properties. This compound is widely utilized as a precursor in the development of pharmaceutical candidates and agrochemical agents, as well as in structure-activity relationship studies and compound library diversification.\u003c\/p\u003e\n\u003cp\u003e*Asumsi: Kondisi penyimpanan standar untuk reagen organik laboratorium, bukan penyimpanan khusus suhu rendah.*\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48085915926746,"sku":"TCI2510B603112832","price":633000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48085915959514,"sku":"TCI2510B603112833","price":2221000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6031.jpg?v=1768815959"},{"product_id":"tci2510b612012935","title":"TCI B6120 2794-60-7 Barium(II) Trifluoromethanesulfonate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eBarium(II) Trifluoromethanesulfonate (CAS 2794-60-7) is a high-purity Lewis acid catalyst widely utilized in organic synthesis for activating carbonyl groups and facilitating carbon-carbon bond formation under mild conditions. This compound serves as a key reagent in Friedel-Crafts acylation, aldol condensations, and various fluorinated building block syntheses. Its stability and ease of handling make it a reliable choice for research laboratories working with fluorinated intermediates and catalytic transformations.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48085920776410,"sku":"TCI2510B612012935","price":1920000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48085920809178,"sku":"TCI2510B612012936","price":5755000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6120.jpg?v=1768204486"},{"product_id":"tci2510b648213381","title":"TCI B6482 1261588-73-1 3,3'-Bis(trifluoromethoxy)-1,1'-biphenyl","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6482, 3,3'-Bis(trifluoromethoxy)-1,1'-biphenyl (CAS 1261588-73-1), is a fluorinated biaryl building block bearing two meta-positioned trifluoromethoxy groups. The rigid biphenyl core combined with the electron-withdrawing, lipophilic –OCF₃ substituents makes it a useful scaffold for medicinal chemistry, agrochemical research, and organic materials development. It is typically elaborated through directed metalation, halogenation, or cross-coupling chemistry in multi-step synthetic routes. AMI Scientific supplies this product in 1 g and 10 g pack sizes for Indonesian research laboratories.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eRUZICKA et al. (1996). ChemInform Abstract: Synthesis and Toxicity of 1,2‐Bis(trifluoromethoxy)‐1,1,3,3,3‐ pentafluoropropane.. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.199629081\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.199629081\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eRuzicka et al. (1996). Synthesis and toxicity of 1,2-bis(trifluoromethoxy)-1,1,3,3,-pentafluoropropane. \u003cem\u003eJournal of Fluorine Chemistry\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1016\/0022-1139(95)03374-2\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1016\/0022-1139(95)03374-2\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48085942665434,"sku":"TCI2510B648213381","price":1263000.0,"currency_code":"IDR","in_stock":true},{"title":"10g","offer_id":48085942698202,"sku":"TCI2510B648213382","price":10095000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6482.jpg?v=1769180270"},{"product_id":"tci2510b650313406","title":"TCI B6503 366008-67-5 2,5-Bis(trifluoromethyl)terephthalic Acid","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6503 2,5-Bis(trifluoromethyl)terephthalic Acid (CAS 366008-67-5) is a fluorinated aromatic dicarboxylic acid used as a versatile synthetic building block. The two trifluoromethyl groups impart strong electron-withdrawing character, making the scaffold useful in medicinal chemistry and functional materials work. Its dicarboxylic acid framework also lends itself to linker chemistry and further derivatisation into esters and amides. Available in 1 g and 5 g packs, it should be weighed in a well-ventilated area and stored cool and dry as directed on the manufacturer's label.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHuang et al. (2023). Synthesis, crystal structure and properties of Mn\/Ni\/Co 3D network structures based on 2, 5-bis(trifluoromethyl) terephthalic acid ligands. \u003cem\u003eInorganica Chimica Acta\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1016\/j.ica.2023.121672\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1016\/j.ica.2023.121672\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e(2018). 2,4-Bis(trifluoromethyl)phenylboronic Acid Catalyzed Amidation. \u003cem\u003eSynfacts\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1055\/s-0037-1611431\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1055\/s-0037-1611431\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHEUER et al. (1990). ChemInform Abstract: Preparation of Bis(2,4‐bis(trifluoromethyl)phenyl)fluorophosphine (III) and 2,4‐Bis(trifluoromethyl)phenyl(2,6‐bis(trifluoromethyl)phenyl)fluorophosphine (IV) ‐ Two Distillable Monofluorophosphines. Structure of cis‐Dichlorobis(bis(2,4‐bis‐(trifluoromethyl)phenyl)fluorophosphino)platinum(II) (VI).. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.199027261\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.199027261\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48085943615706,"sku":"TCI2510B650313406","price":3005000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48085943648474,"sku":"TCI2510B650313407","price":11256000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6503.jpg?v=1768816066"},{"product_id":"tci2510b655513484","title":"TCI B6555 2833773-74-1 2,8-Bis(trifluoromethoxy)dibenzothiophene","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6555 is 2,8-bis(trifluoromethoxy)dibenzothiophene, a fluorinated tricyclic building block carrying two OCF₃ groups on a sulfur-containing conjugated core. Trifluoromethoxy substituents are highly valued for the metabolic stability and lipophilicity they impart in medicinal chemistry, and for the electronic tuning they provide in organic materials. Its symmetric substitution pattern simplifies downstream functionalisation, while the sulfur centre can be oxidised to the sulfoxide or sulfone to modulate electronic properties. AMI Scientific supplies this TCI product in 1 g and 10 g pack sizes; consult the official TCI documentation and safety data sheet before use.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eRUZICKA et al. (1996). ChemInform Abstract: Synthesis and Toxicity of 1,2‐Bis(trifluoromethoxy)‐1,1,3,3,3‐ pentafluoropropane.. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.199629081\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.199629081\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eRuzicka et al. (1996). Synthesis and toxicity of 1,2-bis(trifluoromethoxy)-1,1,3,3,-pentafluoropropane. \u003cem\u003eJournal of Fluorine Chemistry\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1016\/0022-1139(95)03374-2\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1016\/0022-1139(95)03374-2\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMudshinge et al. (2022). Synthesis and applications of S-(trifluoromethyl)-2,8-bis(trifluoromethoxy)dibenzothiophenium triflate (Umemoto reagent IV). \u003cem\u003eJournal of Fluorine Chemistry\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1016\/j.jfluchem.2022.110015\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1016\/j.jfluchem.2022.110015\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48085947056346,"sku":"TCI2510B655513484","price":2297000.0,"currency_code":"IDR","in_stock":true},{"title":"10g","offer_id":48085947089114,"sku":"TCI2510B655513485","price":18826000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6555.jpg?v=1767093894"},{"product_id":"tci2510b662713585","title":"TCI B6627 368-43-4 Benzenesulfonyl Fluoride","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6627 Benzenesulfonyl Fluoride (CAS 368-43-4) is a core SuFEx click chemistry reagent supplied by TCI and available at AMI Scientific. The S–F bond offers greater hydrolytic stability than the corresponding sulfonyl chloride while remaining selectively activatable, enabling clean sulfonamide and sulfonate ester formation. It is widely used in chemical biology as a covalent labelling reagent and in studies of serine-residue enzyme modification. Offered in 1 g and 5 g packs, it must be stored tightly closed in a cool, dry place away from moisture, amines, and strong bases.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e(2007). 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (AEBSF). \u003cem\u003eCold Spring Harbor Protocols\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1101\/pdb.caut2453\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1101\/pdb.caut2453\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e(2007). AEBSF (4-[2-Aminoethyl]benzenesulfonyl fluoride hydrochloride). \u003cem\u003eCold Spring Harbor Protocols\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1101\/pdb.caut856\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1101\/pdb.caut856\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWagner (2023). Preparation of 4-(5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonyl fluoride (ArSO2F). \u003cem\u003eOrganic Syntheses\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.15227\/orgsyn.100.0382\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.15227\/orgsyn.100.0382\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48085950922970,"sku":"TCI2510B662713585","price":1289000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48085950955738,"sku":"TCI2510B662713586","price":4494000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6627.jpg?v=1767094055"},{"product_id":"tci2510b677613697","title":"TCI B6776 1402232-83-0 tert-Butyl 7'-Fluoro-1',4'-dihydro-2'H-spiro[piperidine-4,3'-quinoline]-1-carboxylate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6776 (CAS 1402232-83-0) is a Boc-protected fluorinated spiro[piperidine-quinoline] building block designed for medicinal chemistry programs. Its rigid, sp3-rich spirocyclic core offers three-dimensional character that is valuable for exploring new chemical space. The free anilinic nitrogen provides a convenient handle for acylation, sulfonylation, or alkylation during library synthesis. AMI Scientific offers this TCI reagent in a 100 mg pack size for research-scale synthesis.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eMeng et al. (2017). tert-Butyl (2S,3R,4R)-7′-bromo-4-methyl-2′,5-dioxo-4,5-dihydro-3H-spiro[furan-2,3′-indoline]-3-carboxylate. \u003cem\u003eIUCrData\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1107\/s2414314617004126\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1107\/s2414314617004126\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHoffmann et al. (1998). Separation of (R)‐ and (S)‐tert‐butyl 2‐tert‐butyl‐4‐methoxy‐2,5‐dihydro‐1,3‐imidazole‐1‐carboxylate (building block for amino acid synthesis) by preparative high performance liquid chromatography on a polysaccharide stationary phase. \u003cem\u003eChirality\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/(sici)1520-636x(1998)10:3\u0026lt;217::aid-chir3\u0026gt;3.3.co;2-r\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/(sici)1520-636x(1998)10:3\u0026lt;217::aid-chir3\u0026gt;3.3.co;2-r\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eK. dkk. (2025). Synthesis and Characterization of tert-butyl 3-(((2-hydroxynaphthalen1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1- carboxylate: A piperidine clubbed Boc protected versatile building block for multi functionalized chemical reactions. \u003cem\u003eJournal of Applied Research and Technology\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.22201\/icat.24486736e.2025.23.1.2611\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.22201\/icat.24486736e.2025.23.1.2611\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"100mg","offer_id":48085955739866,"sku":"TCI2510B677613697","price":6840000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6776.jpg?v=1771058548"},{"product_id":"tci2510b677713698","title":"TCI B6777 1402232-95-4 tert-Butyl 5'-Fluoro-1',4'-dihydro-2'H-spiro[piperidine-4,3'-quinoline]-1-carboxylate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6777 (CAS 1402232-95-4) is the 5'-fluoro positional isomer within the Boc-protected spiro[piperidine-quinoline] building block family. Its rigid spirocyclic framework combines a piperidine and a tetrahydroquinoline unit, delivering high three-dimensional character for drug discovery work. Paired with the 7'-fluoro analogue, it helps chemists map how fluorine placement influences physicochemical and biological properties. AMI Scientific supplies this TCI reagent in a 100 mg pack size for research laboratories.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eMamat et al. (2012). Synthesis and Molecular Structure of tert-Butyl 4-(2-tert-butoxy-2-oxoethyl)piperazine-1-carboxylate. \u003cem\u003eCrystals\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.3390\/cryst2010090\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.3390\/cryst2010090\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMeng et al. (2017). tert-Butyl (2S,3R,4R)-7′-bromo-4-methyl-2′,5-dioxo-4,5-dihydro-3H-spiro[furan-2,3′-indoline]-3-carboxylate. \u003cem\u003eIUCrData\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1107\/s2414314617004126\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1107\/s2414314617004126\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHoffmann et al. (1998). Separation of (R)‐ and (S)‐tert‐butyl 2‐tert‐butyl‐4‐methoxy‐2,5‐dihydro‐1,3‐imidazole‐1‐carboxylate (building block for amino acid synthesis) by preparative high performance liquid chromatography on a polysaccharide stationary phase. \u003cem\u003eChirality\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/(sici)1520-636x(1998)10:3\u0026lt;217::aid-chir3\u0026gt;3.3.co;2-r\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/(sici)1520-636x(1998)10:3\u0026lt;217::aid-chir3\u0026gt;3.3.co;2-r\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"100mg","offer_id":48085955805402,"sku":"TCI2510B677713698","price":6840000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6777.jpg?v=1768816103"},{"product_id":"tci2510b686813769","title":"TCI B6868 511540-64-0 5-Bromo-2-[difluoro(3,4,5-trifluorophenoxy)methyl]-1,3-difluorobenzene","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6868 (CAS 511540-64-0) is a highly fluorinated aromatic building block featuring an aryl bromide handle together with an –OCF₂– bridge linking two fluorinated rings. The bromine substituent makes it a practical starting point for palladium-catalysed cross-coupling reactions, while the fluorinated framework is of interest in advanced materials research. It is supplied by TCI in 5 g and 25 g pack sizes for both exploratory and preparative work. Please refer to the manufacturer's Certificate of Analysis and Safety Data Sheet for exact specifications and handling requirements.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eKumawat et al. (2024). Accessing structurally diverse aryl difluoromethyl ethers with bromo(difluoro)acetic acid. \u003cem\u003eChemical Communications\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1039\/d4cc04782f\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1039\/d4cc04782f\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":50506866000090,"sku":"TCI2510B686813769","price":1742000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6868.jpg?v=1768816108"},{"product_id":"tci2510b687913783","title":"TCI B6879 885453-49-6 4-Bromo-2-chloro-6-fluoroaniline","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6879 (CAS 885453-49-6) is 4-bromo-2-chloro-6-fluoroaniline, a trihalogenated aniline offering three differentiated reaction handles on a single ring. The bromine is generally the most reactive site in palladium-catalysed cross-coupling, allowing chemists to functionalise stepwise while retaining the chloro and fluoro substituents. The free amino group supports acylation, sulfonylation, diazotisation and cyclisation routes to fused heterocycles. Available from TCI in 5 g and 25 g packs, it should be stored cool, dry and protected from light, with handling carried out in a fume hood.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSingh et al. (2020). Facile synthesis of bromo- and mixed bromo\/chloro dibenzo-p-dioxins and [14C]-labeled 1,3,7,8-tetrabromodibenzo-p-dioxin. \u003cem\u003eChemosphere\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1016\/j.chemosphere.2019.124626\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1016\/j.chemosphere.2019.124626\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48085959639258,"sku":"TCI2510B687913783","price":2524000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48085959672026,"sku":"TCI2510B687913784","price":8834000.0,"currency_code":"IDR","in_stock":true}]},{"product_id":"tci2510b689313792","title":"TCI B6893 1466514-89-5 2-Bromo-1-(3-fluoro-3-methylazetidin-1-yl)ethan-1-one","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e2-Bromo-1-(3-fluoro-3-methylazetidin-1-yl)ethan-1-one is a synthetic organic compound developed specifically as a fluorinated building block for medicinal chemistry and the synthesis of bioactive compounds. The molecule combines two important functional elements within a single compact framework: a highly nucleophile-reactive α-bromoacetyl group, and a four-membered azetidine ring carrying both fluorine and methyl substituents at the third position. In the laboratory, this compound serves as a linking reagent that allows researchers to introduce a fluorinated azetidine motif into a target molecule in only one or two reaction steps, shortening synthetic routes that are normally long and complicated.\u003c\/p\u003e\n\u003cp\u003eThe characteristics that make this compound a frequent choice lie in its combination of reactivity and structural value. The carbon–bromine bond positioned alpha to the carbonyl group is strongly electrophilic, so it is readily displaced by nucleophiles such as amines, thiols, phenols, and heterocyclic anions under relatively mild reaction conditions. At the same time, the azetidine ring contributes conformational rigidity and a three-dimensional vector that differs from those offered by piperidine or pyrrolidine rings, giving chemists an alternative way to explore spatial arrangement around a scaffold. The fluorine and methyl substituents on the same ring carbon further define the character of that fragment.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this building block is typically used in academic and industrial research settings that focus on organic synthesis and medicinal chemistry, including university research groups, pharmaceutical development units, and contract research facilities. It is normally handled at small scale on the bench, in fume hoods equipped for routine organic synthesis, and used in exploratory route development where a fluorinated azetidine fragment must be attached to a larger molecular framework efficiently.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eMedicinal chemistry scaffold assembly — the compound attaches a fluorinated azetidine fragment to a lead structure in a single alkylation step, shortening routes that would otherwise require multiple protection and deprotection stages.\u003c\/li\u003e\n\u003cli\u003eNucleophilic substitution with amines — the electrophilic α-bromo position reacts readily with primary and secondary amines under mild conditions, making it a convenient reagent for building amide-linked amine derivatives.\u003c\/li\u003e\n\u003cli\u003eThiol and phenol alkylation — soft sulfur nucleophiles and phenolate anions displace the bromide efficiently, allowing researchers to prepare thioether and aryl ether linkages bearing the azetidine carbonyl unit.\u003c\/li\u003e\n\u003cli\u003eHeterocycle functionalization — heterocyclic anions can be alkylated at nitrogen or carbon using this reagent, introducing the fluorinated azetidinyl ketone motif onto ring systems common in bioactive compound programs.\u003c\/li\u003e\n\u003cli\u003eStructure–activity relationship exploration — the rigid four-membered ring provides a three-dimensional vector distinct from piperidine or pyrrolidine analogues, helping chemists probe how spatial orientation affects biological activity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eProduct code: B6893\u003c\/li\u003e\n\u003cli\u003eCAS Number: 1466514-89-5\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Building Blocks \u0026gt; Fluorinated Building Blocks\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in standard research-scale catalogue pack sizes; please confirm the current options when ordering\u003c\/li\u003e\n\u003cli\u003eStorage: keep in a tightly closed original container under the conditions stated on the product label and Safety Data Sheet\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the container tightly closed in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible materials, following the storage conditions printed on the product label and Safety Data Sheet. Keep the material in its original supplier container or in a chemically compatible sealed vessel, and protect it from moisture. As an α-halo carbonyl compound, it should be treated as a reactive and potentially irritating substance: handle it inside a fume hood, wear appropriate gloves, safety goggles, and a laboratory coat, and avoid contact with skin, eyes, and clothing. Weigh and transfer quantities carefully, close containers immediately after use, and dispose of residues and contaminated consumables through the laboratory's designated chemical waste stream. Review the Safety Data Sheet before first use.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"500mg","offer_id":48085959966938,"sku":"TCI2510B689313792","price":8834000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6893.jpg?v=1767094365"},{"product_id":"tci2510b697013849","title":"TCI B6970 175136-66-0 Bis[3,5-bis(trifluoromethyl)phenyl]methanone","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6970 is bis[3,5-bis(trifluoromethyl)phenyl]methanone, a strongly electron-poor diaryl ketone carrying four trifluoromethyl groups. The 3,5-bis(trifluoromethyl)phenyl motif is widely used to tune acidity, lipophilicity, and oxidative stability in ligands, catalysts, and drug candidates. Its carbonyl group serves as a versatile entry point for reduction or addition with organometallic reagents. AMI Scientific offers this TCI fluorinated building block in a 1 g pack; keep it tightly sealed in a cool, dry, light-protected place.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHEUER et al. (1990). ChemInform Abstract: Preparation of Bis(2,4‐bis(trifluoromethyl)phenyl)fluorophosphine (III) and 2,4‐Bis(trifluoromethyl)phenyl(2,6‐bis(trifluoromethyl)phenyl)fluorophosphine (IV) ‐ Two Distillable Monofluorophosphines. Structure of cis‐Dichlorobis(bis(2,4‐bis‐(trifluoromethyl)phenyl)fluorophosphino)platinum(II) (VI).. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.199027261\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.199027261\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSülü dkk. (2001). Acetalization and Transacetalization Reactions Catalyzed by Ruthenium, Rhodium, and Iridium Complexes with {2-{{Bis[3-(trifluoromethyl)phenyl]phosphino}methyl}-2-methylpropane- 1,3-diyl}bis[bis[3-(trifluoromethyl)phenyl]phosphine] (MeC[CH2P(m-CF3C6H4)2]3). \u003cem\u003eHelvetica Chimica Acta\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/1522-2675(20010418)84:4\u0026lt;898::aid-hlca898\u0026gt;3.0.co;2-v\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/1522-2675(20010418)84:4\u0026lt;898::aid-hlca898\u0026gt;3.0.co;2-v\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48276756988122,"sku":"TCI2510B697013849","price":1844000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6970.jpg?v=1767094447"},{"product_id":"tci2510b705013884","title":"TCI B7050 108574-98-7 4-Bromo-2,3,5,6-tetrafluorobenzaldehyde","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B7050 4-Bromo-2,3,5,6-tetrafluorobenzaldehyde is a versatile fluorinated building block carrying an aryl bromide, an aldehyde, and a fully fluorinated ring. The bromide supports palladium-catalyzed cross-couplings, while the electron-poor ring facilitates nucleophilic aromatic substitution. The aldehyde group provides an additional handle for condensations, olefinations, and reductive aminations. Available in 1 g and 5 g packs, it should be kept tightly closed, cool, and dry.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48085964423386,"sku":"TCI2510B705013884","price":1389000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48085964456154,"sku":"TCI2510B705013885","price":4821000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B7050.jpg?v=1769144601"},{"product_id":"tci2510c099115361","title":"TCI C0991 1895-39-2 Sodium Chlorodifluoroacetate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C0991 Sodium Chlorodifluoroacetate (CAS 1895-39-2) is a solid fluorinated building block widely used as an in-situ difluorocarbene source. On heating it enables gem-difluorocyclopropanation of alkenes and difluoromethylation of nucleophiles such as phenols, thiols and amines. AMI Scientific offers this TCI product in 25 g, 100 g and 500 g pack sizes to suit exploratory through repeated synthetic work. Keep the container tightly closed, ensure adequate venting during heated reactions, and follow the manufacturer's label and safety data sheet.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eMehta et al. (2014). ChemInform Abstract: S‐, N‐, and Se‐Difluoromethylation Using Sodium Chlorodifluoroacetate.. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.201410085\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.201410085\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMehta et al. (2013). S-, N-, and Se-Difluoromethylation Using Sodium Chlorodifluoroacetate. \u003cem\u003eOrganic Letters\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1021\/ol402370f\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1021\/ol402370f\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWilliams et al. (2015). ChemInform Abstract: Mild Chlorodifluoroacylation of Indoles via Self‐Activation of Sodium Chlorodifluoroacetate.. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.201505133\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.201505133\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":50506856431834,"sku":"TCI2510C099115361","price":1439000.0,"currency_code":"IDR","in_stock":true},{"title":"100g","offer_id":50506856464602,"sku":"TCI2510C099115362","price":4216000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C0991.jpg?v=1771058100"},{"product_id":"tci2510c099215364","title":"TCI C0992 434-75-3 2-Chloro-6-fluorobenzoic Acid","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C0992 2-Chloro-6-fluorobenzoic Acid (CAS 434-75-3) is a fluorinated benzoic acid bearing halogen substituents at both ortho positions relative to the carboxyl group. The carboxyl group is readily converted into esters, amides or acid chlorides, while the halogens tune the electronic character of the resulting scaffold. AMI Scientific supplies this TCI item in a 10 g pack size suited to laboratory-scale research and intermediate development. Refer to the manufacturer's label and safety data sheet for authoritative specifications and safe handling instructions.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"10g","offer_id":48086042476762,"sku":"TCI2510C099215364","price":884000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C0992.jpg?v=1768816389"},{"product_id":"tci2510c100215379","title":"TCI C1002 668-45-1 2-Chloro-6-fluorobenzonitrile","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1002 2-Chloro-6-fluorobenzonitrile (CAS 668-45-1) is a fluorinated aromatic building block carrying a nitrile flanked by chlorine and fluorine at both ortho positions. The strongly electron-withdrawing cyano group activates the ring so that nucleophiles displace fluorine preferentially, leaving the chlorine available for later palladium-catalysed cross-coupling. The nitrile itself can be hydrolysed, reduced, or cyclised with ortho nucleophiles to reach quinazoline and indazole scaffolds. AMI Scientific offers 5 g and 25 g packs; weigh the solid in a fume hood and store it tightly closed in a cool, dry, light-protected place.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086043033818,"sku":"TCI2510C100215379","price":784000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086043066586,"sku":"TCI2510C100215380","price":1818000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1002.jpg?v=1768816393"},{"product_id":"tci2510c100315381","title":"TCI C1003 368-77-4 3-(Trifluoromethyl)benzonitrile","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1003 3-(Trifluoromethyl)benzonitrile (CAS 368-77-4) is an electron-poor fluorinated building block bearing a trifluoromethyl group meta to the nitrile. The nitrile is readily converted into benzoic acids, benzylamines, tetrazoles, or aryl ketones, giving chemists several divergent routes from a single starting material. The CF₃ substituent is widely used to raise lipophilicity and improve metabolic stability in drug discovery and functional materials research. AMI Scientific supplies this TCI reagent in a 25 g pack; handle it in a fume hood and store it tightly closed in a cool, dry, well-ventilated place.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLi et al. (2009). An Efficient Synthetic Process for Scale-Up Production of 4,5-Diamino-2-(trifluoromethyl)benzonitrile and 5-Bromo-3-(trifluoromethyl)benzene-1,2-diamine. \u003cem\u003eOrganic Process Research \u0026amp; Development\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1021\/op9000498\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1021\/op9000498\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eS. Valli Chitra et al. (2026). 3-Chloro-5-(trifluoromethyl)benzonitrile: Spectroscopic Progression and Evaluation by Density Functional Theory. \u003cem\u003eJournal of Scientific Research\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.3329\/jsr.v18i1.83645\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.3329\/jsr.v18i1.83645\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHu et al. (2008). ChemInform Abstract: (1R,2S)‐4‐(2‐Cyano‐cyclohexyl‐oxy)‐2‐trifluoromethyl‐benzonitrile, a Potent Androgen Receptor Antagonist for Stimulating Hair Growth and Reducing Sebum Production.. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.200806073\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.200806073\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48086043132122,"sku":"TCI2510C100315381","price":1389000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1003.jpg?v=1768816394"},{"product_id":"tci2510c100415382","title":"TCI C1004 447-60-9 2-(Trifluoromethyl)benzonitrile","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1004 2-(Trifluoromethyl)benzonitrile (CAS 447-60-9) is the ortho isomer of the trifluoromethylbenzonitrile series, placing the CF₃ group directly adjacent to the nitrile. This proximity provides both steric and electronic influence and enables intramolecular cyclisations that the meta and para isomers cannot offer. The nitrile can also be converted into benzoic acids, amides, benzylamines, amidines, or tetrazoles depending on the synthetic route. AMI Scientific stocks 5 g and 25 g packs; handle the material in a fume hood and store it tightly closed in a cool, dry, well-ventilated place.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLi et al. (2009). An Efficient Synthetic Process for Scale-Up Production of 4,5-Diamino-2-(trifluoromethyl)benzonitrile and 5-Bromo-3-(trifluoromethyl)benzene-1,2-diamine. \u003cem\u003eOrganic Process Research \u0026amp; Development\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1021\/op9000498\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1021\/op9000498\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eS. Valli Chitra et al. (2026). 3-Chloro-5-(trifluoromethyl)benzonitrile: Spectroscopic Progression and Evaluation by Density Functional Theory. \u003cem\u003eJournal of Scientific Research\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.3329\/jsr.v18i1.83645\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.3329\/jsr.v18i1.83645\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHu et al. (2008). ChemInform Abstract: (1R,2S)‐4‐(2‐Cyano‐cyclohexyl‐oxy)‐2‐trifluoromethyl‐benzonitrile, a Potent Androgen Receptor Antagonist for Stimulating Hair Growth and Reducing Sebum Production.. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.200806073\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.200806073\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086043197658,"sku":"TCI2510C100415382","price":784000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086043230426,"sku":"TCI2510C100415383","price":1995000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1004.jpg?v=1768816395"},{"product_id":"tci2510c100515384","title":"TCI C1005 455-18-5 4-(Trifluoromethyl)benzonitrile","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1005 4-(Trifluoromethyl)benzonitrile (CAS 455-18-5) is the para isomer of the trifluoromethylbenzonitrile family, giving a linear, electron-poor aromatic building block with a well-defined dipole. Its nitrile group is readily converted into 4-(trifluoromethyl)benzoic acid, the corresponding benzylamine, tetrazoles, or aryl ketones via organometallic addition. The absence of steric interaction between the two substituents makes reactions on this scaffold clean and predictable, which suits routine synthetic work. AMI Scientific offers 5 g and 25 g packs; handle in a fume hood and store tightly closed in a cool, dry, well-ventilated place.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086043263194,"sku":"TCI2510C100515384","price":455000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086043295962,"sku":"TCI2510C100515385","price":1313000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1005.jpg?v=1769144526"},{"product_id":"tci2510c102415408","title":"TCI C1024 367-21-5 3-Chloro-4-fluoroaniline","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1024 3-Chloro-4-fluoroaniline (CAS 367-21-5) is a dihalogenated aniline widely used as a fluorinated building block in pharmaceutical and agrochemical research. Its aromatic amine undergoes standard acylation, sulfonylation, reductive alkylation, and diazotisation chemistry, while the halogen pattern tunes the electronic character of the ring. AMI Scientific provides this TCI reagent in 25 g and 500 g packs to match both exploratory and repeat-scale synthesis. Anilines can be absorbed through the skin, so handle the material in a fume hood with chemical-resistant gloves and follow the official TCI Safety Data Sheet.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48086044180698,"sku":"TCI2510C102415408","price":960000.0,"currency_code":"IDR","in_stock":true},{"title":"500g","offer_id":48086044213466,"sku":"TCI2510C102415409","price":7622000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1024.jpg?v=1769144525"},{"product_id":"tci2510c104115427","title":"TCI C1041 350-30-1 3-Chloro-4-fluoronitrobenzene","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e3-Chloro-4-fluoronitrobenzene (TCI C1041, CAS 350-30-1) is a highly activated fluorinated aromatic building block bearing chloro, fluoro, and nitro substituents. The nitro group strongly activates the ring, allowing selective nucleophilic aromatic substitution at the fluorine position with amines, alkoxides, or thiolates. It is widely used to prepare substituted anilines and diversified compound libraries in medicinal and agrochemical research. AMI Scientific offers 25 g and 250 g packs; handle the solid in a fume hood and avoid dust formation during weighing.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48086044901594,"sku":"TCI2510C104115427","price":986000.0,"currency_code":"IDR","in_stock":true},{"title":"250g","offer_id":48086044934362,"sku":"TCI2510C104115428","price":5831000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1041.jpg?v=1768816404"},{"product_id":"tci2510c112115545","title":"TCI C1121 2613-23-2 3-Chloro-4-fluorophenol","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1121 3-Chloro-4-fluorophenol (CAS 2613-23-2) is a halogenated phenol that serves as a compact fluorinated building block. The phenolic hydroxyl supports etherification, esterification, and coupling chemistry, while the aromatic chlorine can act as a handle for palladium catalysed cross coupling. Fluorine substitution is frequently used in medicinal and agrochemical research to tune lipophilicity and metabolic behaviour. AMI Scientific supplies a 10 g pack; store it cool, dry, protected from light, and handle it in a fume hood.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"10g","offer_id":48086049915098,"sku":"TCI2510C112115545","price":1339000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1121.jpg?v=1768816428"},{"product_id":"tci2510c112615552","title":"TCI C1126 37777-76-7 2-Chloro-6-fluorophenylacetic Acid","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1126 2-Chloro-6-fluorophenylacetic Acid (CAS 37777-76-7) is a fluorinated building block carrying both chlorine and fluorine at the ortho positions of the aromatic ring. The carboxylic acid handle enables straightforward amidation, esterification, and acid chloride formation, while the halogen pattern offers distinctive electronic and steric tuning. It is commonly used in medicinal chemistry, agrochemical research, and structure–activity relationship studies. AMI Scientific supplies this TCI product in 5 g and 25 g pack sizes for laboratories across Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086050308314,"sku":"TCI2510C112615552","price":758000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086050341082,"sku":"TCI2510C112615553","price":2399000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1126.jpg?v=1769144511"},{"product_id":"tci2510c116115600","title":"TCI C1161 2106-02-7 2-Chloro-4-fluoroaniline","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e2-Chloro-4-fluoroaniline (TCI C1161, CAS 2106-02-7) is a halogenated aniline bearing chlorine at the ortho position and fluorine at the para position relative to the amino group. The free aromatic amine readily undergoes diazotization, acylation, and condensation, while the ring halogens provide handles for cross-coupling chemistry. This combination makes it a frequent intermediate in medicinal chemistry and agrochemical research programmes. Supplied in a 25 g pack, it must be handled with gloves in a fume hood and stored sealed in a cool, dark, well-ventilated area.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48086053519578,"sku":"TCI2510C116115600","price":1792000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1161.jpg?v=1769144509"},{"product_id":"tci2510c116915615","title":"TCI C1169 57946-56-2 4-Chloro-2-fluoroaniline","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e4-Chloro-2-fluoroaniline (TCI C1169, CAS 57946-56-2) is a halogenated aniline with fluorine ortho and chlorine para to the amino group. The ortho fluorine modulates the basicity of the amine while the para chloride offers a convenient handle for palladium-catalysed cross-coupling. Its free primary amine supports acylation, sulfonylation, diazotization, and condensation routes toward nitrogen heterocycles, making it a recurring intermediate in medicinal and agrochemical research. Available in 10 g and 25 g packs, it should be handled with gloves in a fume hood and stored sealed in a cool, dark, well-ventilated place.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"10g","offer_id":48086054109402,"sku":"TCI2510C116915615","price":1112000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086054142170,"sku":"TCI2510C116915616","price":2221000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1169.jpg?v=1769144507"},{"product_id":"tci2510c126115744","title":"TCI C1261 700-37-8 4-Chloro-2-fluoronitrobenzene","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1261 4-Chloro-2-fluoronitrobenzene (CAS 700-37-8) is a highly electron-poor fluorinated building block designed for nucleophilic aromatic substitution chemistry. The ortho nitro group activates the fluorine as an excellent leaving group, allowing amines, alkoxides, and thiolates to react selectively while the chlorine remains available for later cross-coupling. Subsequent reduction of the nitro group gives substituted anilines that are widely used to construct benzimidazoles, benzoxazoles, and related fused heterocycles. AMI Scientific supplies 5 g and 25 g packs; as a halogenated nitroaromatic, it must be handled in a fume hood with strict skin protection.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086059581658,"sku":"TCI2510C126115744","price":934000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086059614426,"sku":"TCI2510C126115745","price":2979000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1261.jpg?v=1768816472"},{"product_id":"tci2510c127515757","title":"TCI C1275 403-16-7 3-Chloro-4-fluorobenzoic Acid","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1275 3-Chloro-4-fluorobenzoic Acid (CAS 403-16-7) is a dihalogenated benzoic acid classified as a fluorinated building block. Its carboxylic acid group supports straightforward amide and ester formation, while the ring fluorine can serve as a leaving group in nucleophilic aromatic substitution. The compound is frequently used in medicinal chemistry, agrochemical intermediate research, and compound library preparation. AMI Scientific offers 5 g and 25 g pack sizes for laboratory-scale work.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086060237018,"sku":"TCI2510C127515757","price":784000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086060269786,"sku":"TCI2510C127515758","price":2500000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1275.jpg?v=1768816474"},{"product_id":"tci2510c129415786","title":"TCI C1294 3874-54-2 4-Chloro-4'-fluorobutyrophenone","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1294 4-Chloro-4'-fluorobutyrophenone is a fluorinated building block that combines an alkyl chloride chain with a para-fluorinated aryl ketone. The chloride is readily displaced by amines and other nucleophiles, while the carbonyl offers a second handle for reduction or ring formation. It is a well-known intermediate for constructing butyrophenone-type side chains in medicinal chemistry research. AMI Scientific offers this TCI reagent in a 25 g pack size suited to laboratory-scale synthesis and route optimisation.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48086061580506,"sku":"TCI2510C129415786","price":733000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1294.jpg?v=1768816477"},{"product_id":"tci2510c131115804","title":"TCI C1311 399-35-9 2'-Chloro-4'-fluoroacetanilide","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1311 2'-Chloro-4'-fluoroacetanilide is a halogenated acetanilide bearing both chlorine and fluorine on the aromatic ring. The acetamide group acts as a protecting and directing group, while the fluorine substituent lets chemists tune electronic character and lipophilicity. It serves as an intermediate toward substituted anilines, cross-coupling substrates, and fluorinated targets in pharmaceutical and agrochemical research. AMI Scientific supplies this TCI product in 5 g and 25 g packs for laboratory use.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086062465242,"sku":"TCI2510C131115804","price":733000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086062498010,"sku":"TCI2510C131115805","price":2550000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1311.jpg?v=1768816483"},{"product_id":"tci2510c135015864","title":"TCI C1350 2252-51-9 2-Chloro-4-fluorobenzoic Acid","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1350 2-Chloro-4-fluorobenzoic Acid (CAS 2252-51-9) is a halogenated benzoic acid derivative widely used as a fluorinated building block in synthetic chemistry. Its carboxylic acid group readily undergoes amidation, esterification, and other standard coupling transformations, while the ring fluorine can serve as a leaving group in nucleophilic aromatic substitution. Researchers commonly apply it in the preparation of heterocyclic scaffolds and in early-stage intermediates for pharmaceutical and agrochemical discovery programs. AMI Scientific offers this TCI reagent in 5 g and 25 g pack sizes to suit both exploratory and larger-scale laboratory work.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086065053914,"sku":"TCI2510C135015864","price":481000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086065086682,"sku":"TCI2510C135015865","price":1642000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1350.jpg?v=1769144488"},{"product_id":"tci2510c138015905","title":"TCI C1380 33462-80-5 (3-Chloropropyl)diphenylsulfonium Tetrafluoroborate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1380 (3-Chloropropyl)diphenylsulfonium Tetrafluoroborate (CAS 33462-80-5) is a sulfonium salt used as a precursor to reactive sulfonium ylides. Deprotonation generates a carbanion whose pendant chloropropyl chain enables intramolecular cyclisation toward cyclopropane and related small-ring frameworks. The tetrafluoroborate counterion provides good stability and solubility in polar aprotic solvents. AMI Scientific offers this TCI reagent in a 1 g pack; keep it dry and tightly closed.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086066626778,"sku":"TCI2510C138015905","price":3005000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1380.jpg?v=1769180344"},{"product_id":"tci2510c142415967","title":"TCI C1424 387-45-1 2-Chloro-6-fluorobenzaldehyde","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1424 2-Chloro-6-fluorobenzaldehyde (CAS 387-45-1) is a doubly halogenated aromatic aldehyde widely used as a fluorinated building block in organic synthesis. Its electron-poor ring and ortho-fluorine substituent make it a practical substrate for nucleophilic aromatic substitution and subsequent ring-closure strategies. Researchers commonly apply it in the preparation of fluorinated heterocycles, pharmaceutical intermediates, and functional organic materials. AMI Scientific supplies this TCI reagent in a laboratory-scale package for research and synthesis use.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"10g","offer_id":48086069018842,"sku":"TCI2510C142415967","price":481000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1424.jpg?v=1768816519"},{"product_id":"tci2510c145816024","title":"TCI C1458 383-62-0 Ethyl Chlorodifluoroacetate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1458 Ethyl Chlorodifluoroacetate (CAS 383-62-0) is a fluorinated ester valued as a practical difluorocarbene precursor. Under suitable conditions it enables difluoromethylation of oxygen, nitrogen, and sulfur nucleophiles, and it also serves directly as a gem-difluoro building block. These transformations are widely applied in pharmaceutical and agrochemical research, where fluorine substitution modulates lipophilicity and metabolic stability. AMI Scientific supplies this TCI product in 25 g and 500 g packs; keep it tightly sealed and protected from moisture as directed by the manufacturer.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBlanco et al. (2016). Atmospheric sink of methyl chlorodifluoroacetate and ethyl chlorodifluoroacetate: temperature dependent rate coefficients, product distribution of their reactions with Cl atoms and CF 2 ClC(O)OH formation. \u003cem\u003eRSC Advances\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1039\/c6ra03454c\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1039\/c6ra03454c\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBEGUE et al. (1995). ChemInform Abstract: Synthesis of 3‐gem‐Difluoro‐2‐ethoxy Allylic Alcohols from Ethyl Chlorodifluoroacetate.. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.199501093\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.199501093\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBégué dkk. (1994). Synthesis of 3-gem-difluoro-2-ethoxy allylic alcohols from ethyl chlorodifluoroacetate. \u003cem\u003eTetrahedron Letters\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1016\/0040-4039(94)88085-9\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1016\/0040-4039(94)88085-9\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":50506852008154,"sku":"TCI2510C145816024","price":1768000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1458.jpg?v=1768204602"},{"product_id":"tci2510c146016027","title":"TCI C1460 110877-64-0 2-Chloro-4,5-difluorobenzoic Acid","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1460 2-Chloro-4,5-difluorobenzoic Acid is a halogenated benzoic acid derivative widely used as a starting material in fluorinated aromatic synthesis. Its carboxylic acid group allows straightforward conversion into esters, amides, and acid chlorides, while the chlorine and fluorine substituents support selective aromatic substitution chemistry. Researchers commonly apply this building block in medicinal chemistry programmes and multi-step organic synthesis. AMI Scientific supplies the material in original TCI packaging across several pack sizes to suit both small-scale screening and routine laboratory work.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086071279834,"sku":"TCI2510C146016027","price":860000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086071312602,"sku":"TCI2510C146016028","price":2349000.0,"currency_code":"IDR","in_stock":true},{"title":"250g","offer_id":48086071345370,"sku":"TCI2510C146016029","price":12519000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1460.jpg?v=1768816530"},{"product_id":"tci2510c146516034","title":"TCI C1465 84194-36-5 2-Chloro-4-fluorobenzaldehyde","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1465 2-Chloro-4-fluorobenzaldehyde is a halogenated aromatic aldehyde used as a versatile intermediate in organic synthesis. The aldehyde group readily undergoes condensation, reduction, and nucleophilic addition, making the compound a common entry point to Schiff bases and heterocyclic scaffolds. Its chlorine and fluorine substituents allow further functionalisation and are frequently exploited in fluorinated medicinal chemistry. AMI Scientific provides the material in original TCI packaging; because aromatic aldehydes are air-sensitive, containers should be kept tightly closed and stored in a cool, dark place.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086071607514,"sku":"TCI2510C146516034","price":633000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48086071640282,"sku":"TCI2510C146516035","price":1868000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1465.jpg?v=1768816532"},{"product_id":"tci2510c146716037","title":"TCI C1467 401-56-9 Ethyl Chlorofluoroacetate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1467 Ethyl Chlorofluoroacetate is a halogenated acetate ester bearing both chlorine and fluorine at the alpha carbon. It is valued as a reagent for introducing monofluorinated carbon units into target molecules through alkylation, condensation, and cyclisation chemistry. The ester group can be further converted into acids, amides, or alcohols, giving flexibility across multi-step synthetic routes. AMI Scientific supplies this liquid reagent in original TCI packaging, and it should be handled in a fume hood with full personal protective equipment because haloacetate esters are strongly irritating.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLi et al. (2021). Nickel‐Catalyzed Cross‐Coupling of Ethyl Chlorofluoroacetate with Aryl Bromides. \u003cem\u003eChemistry – An Asian Journal\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/asia.202100348\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/asia.202100348\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086071738586,"sku":"TCI2510C146716037","price":1062000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086071771354,"sku":"TCI2510C146716038","price":3155000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1467.jpg?v=1769144470"},{"product_id":"tci2510c149816079","title":"TCI C1498 34328-61-5 3-Chloro-4-fluorobenzaldehyde","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1498 3-Chloro-4-fluorobenzaldehyde is a dihalogenated aromatic aldehyde bearing a chlorine at the meta position and a fluorine at the para position relative to the formyl group. This substitution pattern provides three complementary reactive handles: a versatile aldehyde, an activated fluorine suited to nucleophilic aromatic substitution, and a chlorine available for cross-coupling chemistry. It is widely applied in medicinal chemistry, agrochemical research, and heterocycle construction, including reductive amination, Wittig-type olefination, and Schiff base formation. AMI Scientific supplies this TCI fluorinated building block in 5 g and 25 g packs, and users should refer to the manufacturer's label and Safety Data Sheet for complete technical and safety details.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086073737434,"sku":"TCI2510C149816079","price":455000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086073770202,"sku":"TCI2510C149816080","price":1339000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1498.jpg?v=1768816546"},{"product_id":"tci2510c150316088","title":"TCI C1503 2834-23-3 Chlorodifluoroacetic Anhydride","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1503 Chlorodifluoroacetic Anhydride is a highly reactive fluorinated acid anhydride used as a powerful acylating agent for alcohols, amines, and phenols. It transfers the chlorodifluoroacetyl fragment efficiently and also serves as an entry point to difluorocarbene chemistry and difluorinated motifs in medicinal and agrochemical research. Its halogenated acyl group is additionally valuable for analytical derivatization, improving volatility and detector response in gas chromatography. AMI Scientific offers this TCI reagent in 10 g and 25 g packs; because it reacts rapidly with moisture, it must be handled with dry, inert-atmosphere technique in strict accordance with the manufacturer's Safety Data Sheet.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eKawamura et al. (2018). Reactivity and properties of bis(chlorodifluoroacetyl) peroxide generated in situ from chlorodifluoroacetic anhydride for chlorodifluoromethylation reactions. \u003cem\u003eChemical Communications\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1039\/c8cc05905e\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1039\/c8cc05905e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"10g","offer_id":48086074097882,"sku":"TCI2510C150316088","price":1818000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086074130650,"sku":"TCI2510C150316089","price":3181000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1503.jpg?v=1769180351"},{"product_id":"tci2510c150616092","title":"TCI C1506 5527-95-7 4-Chloro-3-fluorobenzaldehyde","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1506 4-Chloro-3-fluorobenzaldehyde is a dihalogenated aromatic aldehyde with chlorine at the para position and fluorine at the meta position relative to the formyl group. It complements the 3-chloro-4-fluoro isomer, letting chemists select the halogen orientation best suited to their synthetic target. The aldehyde supports condensation, Wittig and HWE olefination, reductive amination, and heterocycle construction, while the aryl chloride remains available for palladium-catalyzed cross-coupling. AMI Scientific supplies this TCI fluorinated building block in 1 g, 5 g, and 25 g packs, with all technical and safety details to be confirmed from the manufacturer's official documentation.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086074392794,"sku":"TCI2510C150616092","price":455000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48086074425562,"sku":"TCI2510C150616093","price":1112000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086074458330,"sku":"TCI2510C150616094","price":3660000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1506.jpg?v=1769180353"},{"product_id":"tci2510c151616114","title":"TCI C1516 6294-93-5 2-Chloro-5-hydroxybenzotrifluoride","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1516 2-Chloro-5-hydroxybenzotrifluoride (CAS 6294-93-5) is a fluorinated building block combining a trifluoromethyl group, an aromatic chlorine, and a phenolic hydroxyl on one ring. The phenol offers a handle for etherification and Mitsunobu-type couplings, while the aryl chloride supports palladium-catalysed cross-coupling, enabling planned stepwise elaboration. Trifluoromethyl substitution is frequently used in medicinal and agrochemical design to tune lipophilicity and metabolic stability. Supplied in 1 g and 5 g research packs; always consult the TCI Certificate of Analysis and Safety Data Sheet for the lot you receive.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086075179226,"sku":"TCI2510C151616114","price":505000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48086075211994,"sku":"TCI2510C151616115","price":1666000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1516.jpg?v=1769144463"},{"product_id":"tci2510c157016200","title":"TCI C1570 347-93-3 3-Chloro-4'-fluoropropiophenone","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1570 3-Chloro-4'-fluoropropiophenone is a fluorinated building block bearing both a reactive ketone and a displaceable β-chloride. It is most often used to prepare β-aminoketones by substitution with primary or secondary amines, a motif frequently encountered in medicinal chemistry. Selective reduction followed by ring closure also provides convenient access to fluorinated epoxides. AMI Scientific offers this TCI reagent in 5 g and 25 g packs to support both exploratory and repeated synthetic runs.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086078488794,"sku":"TCI2510C157016200","price":633000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086078521562,"sku":"TCI2510C157016201","price":1363000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1570.jpg?v=1768816572"},{"product_id":"tci2510c158616222","title":"TCI C1586 1514-87-0 Methyl Chlorodifluoroacetate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1586 Methyl Chlorodifluoroacetate (CAS 1514-87-0) is a widely used fluorinated building block and a practical precursor for generating difluorocarbene. It enables the introduction of difluoromethylene and difluoromethyl motifs into target molecules, supporting pharmaceutical, agrochemical, and functional materials research. Typical uses include difluoromethylation of phenols and thiols as well as the preparation of fluorinated cyclopropanes. AMI Scientific supplies this TCI reagent in 5 g and 25 g packages; please observe the handling precautions in the official TCI Safety Data Sheet.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSU et al. (1992). ChemInform Abstract: Methyl Chlorodifluoroacetate. A Convenient Trifluoromethylating Agent.. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.199231150\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.199231150\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDe-Bao et al. (1991). Methyl chlorodifluoroacetate a convenient trifluoromethylating agent. \u003cem\u003eTetrahedron Letters\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1016\/0040-4039(91)80566-o\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1016\/0040-4039(91)80566-o\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBlanco et al. (2016). Atmospheric sink of methyl chlorodifluoroacetate and ethyl chlorodifluoroacetate: temperature dependent rate coefficients, product distribution of their reactions with Cl atoms and CF 2 ClC(O)OH formation. \u003cem\u003eRSC Advances\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1039\/c6ra03454c\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1039\/c6ra03454c\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086079701210,"sku":"TCI2510C158616222","price":657000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086079733978,"sku":"TCI2510C158616223","price":1616000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1586.jpg?v=1768204608"},{"product_id":"tci2510c159616238","title":"TCI C1596 2106-05-0 5-Chloro-2-fluoroaniline","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1596 5-Chloro-2-fluoroaniline (CAS 2106-05-0) is a halogenated aniline that combines a primary aromatic amine with both chloro and fluoro substituents. This arrangement makes it a versatile intermediate for nitrogen heterocycle synthesis, amidation and sulfonylation chemistry, diazonium salt preparation, and metal-catalysed coupling. Halogenated anilines of this type are frequently used in pharmaceutical and agrochemical research programmes. AMI Scientific supplies this TCI reagent in 5 g and 25 g packages; handle in a fume hood and follow the official TCI Safety Data Sheet at all times.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086080258266,"sku":"TCI2510C159616238","price":481000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086080291034,"sku":"TCI2510C159616239","price":1541000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1596.jpg?v=1771058353"},{"product_id":"tci2510c159716240","title":"TCI C1597 61072-56-8 4-Chloro-2-fluorobenzaldehyde","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1597 4-Chloro-2-fluorobenzaldehyde (CAS 61072-56-8) is a halogenated aromatic aldehyde that serves as a versatile fluorinated building block. Its reactive aldehyde group supports condensation reactions, imine formation, reductive amination, and multi-component heterocycle synthesis. The ortho fluorine also enables nucleophilic aromatic substitution, while the chloro substituent offers a handle for further coupling chemistry. AMI Scientific supplies this TCI reagent in 5 g and 25 g packages; store tightly sealed and consult the official TCI Safety Data Sheet before handling.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086080323802,"sku":"TCI2510C159716240","price":986000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086080356570,"sku":"TCI2510C159716241","price":3005000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1597.jpg?v=1768816580"},{"product_id":"tci2510c159816242","title":"TCI C1598 1996-41-4 2-Chloro-4-fluorophenol","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1598 2-Chloro-4-fluorophenol (CAS 1996-41-4) is a halogenated phenol that functions as a flexible fluorinated building block. Its phenolic hydroxyl group is readily converted into aryl ethers and esters, while the chloro and fluoro substituents tune both acidity and ring reactivity. The compound is widely used as an intermediate in pharmaceutical, agrochemical, and fluorine chemistry research. AMI Scientific supplies this TCI reagent in a 25 g package; handle in a fume hood with full personal protective equipment and follow the official TCI Safety Data Sheet.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48086080389338,"sku":"TCI2510C159816242","price":4039000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1598.jpg?v=1769144454"},{"product_id":"tci2510c165916320","title":"TCI C1659 2106-04-9 3-Chloro-2-fluoroaniline","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e3-Chloro-2-fluoroaniline is a versatile organic compound widely used as a building block in chemical synthesis. Its unique structure, featuring both chlorine and fluorine substituents, provides specific reactivity and stability, making it ideal for various chemical reactions. This compound is commonly utilized in the synthesis of fluorinated compounds and derivatives of aniline, particularly in pharmaceutical and medicinal chemistry research. Its solubility in organic solvents enhances its applicability in laboratory settings. Due to its reactivity and functional group compatibility, it is a preferred choice in both academic and industrial research, especially in Indonesia, where it supports advanced chemical studies and innovation.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086083403994,"sku":"TCI2510C165916320","price":934000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086083436762,"sku":"TCI2510C165916321","price":2752000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1659.jpg?v=1769144448"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l3-fluorinated-building-blocks.oembed?page=85","provider":"AMI Scientific","version":"1.0","type":"link"}