{"title":"Calcineurin Inhibitors (Phosphatase activity)","description":"\u003cp\u003e\u003cstrong\u003eCalcineurin Inhibitors (Phosphatase activity)\u003c\/strong\u003e — menghimpun senyawa yang menghambat aktivitas fosfatase kalsineurin, enzim yang berperan dalam jalur transduksi sinyal sel limfosit T. Kelompok ini mencakup makrolida dan peptida siklik yang berasal dari produk fermentasi mikroba.\u003c\/p\u003e\u003cp\u003eCalcineurin Inhibitors dipakai peneliti biologi sel dan imunologi dasar untuk mempelajari jalur pensinyalan kalsineurin-NFAT pada berbagai model eksperimental in vitro, termasuk studi mekanisme aktivasi sel imun. Senyawa seperti Cyclosporin A, Tacrolimus, dan Pimecrolimus umum dipakai sebagai alat riset (research tool) pada kajian jalur fosfatase dan komunikasi antarsel.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510p249348337\"\u003eTCI P2493 137071-32-0 Pimecrolimus\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c240817175\"\u003eTCI C2408 59865-13-3 Cyclosporin A\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510m225840465\"\u003eTCI M2258 109581-93-3 Tacrolimus Monohydrate\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePemilihan memperhatikan bentuk kimia senyawa (misalnya bentuk monohidrat), tingkat kemurnian untuk keperluan penelitian, serta kesesuaiannya dengan desain eksperimen jalur sinyal sel yang dipelajari. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Immunosuppressant Ingredients (for Research and Experimental Use), sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-leukotriene-b4-ltb4-synthsis-inhibitors\"\u003eLeukotriene B4 (LTB4) Synthsis Inhibitors\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-immunocomplex-dissociating-agents\"\u003eImmunocomplex Dissociating Agents\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l4-immunosuppressant-ingredients-for-research-and-experimental-use\"\u003eImmunosuppressant Ingredients (for Research and Experimental Use)\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510c240817175","title":"TCI C2408 59865-13-3 Cyclosporin A","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eCyclosporin A is a biochemical compound widely used in life sciences research. It serves as an active ingredient with potent immunosuppressive properties, making it essential for studies involving the immune system, inflammation, and autoimmune diseases. This compound plays a crucial role in various laboratory experiments, particularly in immunology and pharmacology. Its ability to modulate immune responses has made it a key tool in both basic and applied research settings. Cyclosporin A is also integral to drug development and therapeutic research, especially in the field of biomedicine.\u003c\/p\u003e\n\u003cp\u003eCyclosporin A is valued for its complex structure and stable chemical properties, which ensure consistent performance in laboratory applications. It exhibits good solubility in organic solvents, making it compatible with a wide range of experimental protocols. The compound’s non-toxic nature further enhances its safety profile, allowing researchers to use it without significant risk in controlled laboratory environments. These characteristics make Cyclosporin A a reliable and preferred choice for scientific investigations.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, Cyclosporin A is commonly used in academic and research institutions. It is particularly relevant for studies on immunological mechanisms, drug development, and immunosuppressive therapies. Its versatility and reliability make it a valuable resource for researchers working in life sciences and biomedical fields. The compound is frequently utilized in both teaching and applied research settings across Indonesia.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eImmunological research: Cyclosporin A is ideal for studying immune system modulation due to its strong immunosuppressive activity.\u003c\/li\u003e\n\u003cli\u003eAutoimmune disease studies: It is widely used to investigate the mechanisms of autoimmune disorders and potential therapeutic interventions.\u003c\/li\u003e\n\u003cli\u003ePharmacological research: The compound is essential for drug development and testing, especially in the field of immunosuppressive therapies.\u003c\/li\u003e\n\u003cli\u003eInflammatory response analysis: Cyclosporin A helps researchers understand the role of inflammation in various diseases and conditions.\u003c\/li\u003e\n\u003cli\u003eBiomedical applications: It is a key component in the development of new treatments and therapies for immune-related conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 59865-13-3\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Biochemicals and Reagents \u0026gt; Antibiotics\u003c\/li\u003e\n\u003cli\u003ePack sizes: As per standard laboratory supply formats\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid powder\u003c\/li\u003e\n\u003cli\u003eStorage note: Requires proper storage conditions to maintain stability and potency\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eCyclosporin A should be stored in a cool, dry place away from direct sunlight to maintain its chemical stability. It is recommended to keep the compound in airtight containers to prevent moisture absorption and contamination. Due to its non-toxic nature, it is generally safe to handle, but standard laboratory safety protocols should still be followed. Researchers should ensure proper ventilation when working with the compound and avoid prolonged exposure. The compound should be stored in a secure location to prevent accidental use or contamination. Regular monitoring of storage conditions is advised to ensure the integrity of the material throughout its shelf life.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"100mg","offer_id":48086125117658,"sku":"TCI2510C240817175","price":1378000.0,"currency_code":"IDR","in_stock":true},{"title":"1g","offer_id":48086125150426,"sku":"TCI2510C240817176","price":6999000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C2408.jpg?v=1767098303"},{"product_id":"tci2510m225840465","title":"TCI M2258 109581-93-3 Tacrolimus Monohydrate","description":"\u003cp\u003e\u003cstrong\u003eTacrolimus Monohydrate\u003c\/strong\u003e (CAS 109581-93-3) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eHPLC Grade\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C44H69NO12.H2O\u003c\/li\u003e\n\u003cli\u003eCAS number: 109581-93-3\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;80.0%(HPLC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: M2258\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e FK 506 Monohydrate\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"10mg","offer_id":48087665574106,"sku":"TCI2510M225840465","price":5876000.0,"currency_code":"IDR","in_stock":true},{"title":"50mg","offer_id":48087665606874,"sku":"TCI2510M225840466","price":20490000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510M2258.jpg?v=1768205785"},{"product_id":"tci2510p249348337","title":"TCI P2493 137071-32-0 Pimecrolimus","description":"\u003cp\u003e\u003cstrong\u003ePimecrolimus\u003c\/strong\u003e (CAS 137071-32-0) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eHPLC Grade\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C43H68ClNO11\u003c\/li\u003e\n\u003cli\u003eCAS number: 137071-32-0\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;95.0%(HPLC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: P2493\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e Picrolimus; (1R,9S,12S,13R,14S,17R,18Z,21S,23S,24R,25S,27R)-12-[(1E)-1-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-propen-2-yl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.0~4,9~]octacos-18-ene-2,3,10,16-tetrone\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"200mg","offer_id":48088125800666,"sku":"TCI2510P249348337","price":5509000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510P2493.jpg?v=1768206168"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-calcineurin-inhibitors-phosphatase-activity.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}