{"title":"Channel Blockers","description":"\u003cp\u003e\u003cstrong\u003eChannel Blockers\u003c\/strong\u003e — menghimpun molekul kecil bioaktif dengan beragam kerangka kimia, mulai dari alkaloid alami seperti protopin hingga senyawa sintetik seperti turunan dihidropiridin, yang bekerja pada saluran ion di membran sel. Keragaman strukturnya mencerminkan berbagai target saluran ion yang berbeda.\u003c\/p\u003e\u003cp\u003eChannel blockers ini dipakai peneliti farmakologi dan neurosains dalam studi elektrofisiologi untuk mengamati peran saluran ion natrium, kalsium, atau kalium pada sel saraf dan otot. Senyawa seperti QX 314 dan clevidipine juga menjadi alat riset pada karakterisasi mekanisme kerja senyawa yang menyasar saluran ion.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510a36294461\"\u003eTCI A3629 333963-40-9 Lubiprostone\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b672713654\"\u003eTCI B6727 30484-77-6 Flunarizine Dihydrochloride\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510q011849451\"\u003eTCI Q0118 24003-58-5 QX 314 Bromide\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c350318563\"\u003eTCI C3503 167221-71-8 Clevidipine\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510p261148465\"\u003eTCI P2611 130-86-9 Protopine\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c392319040\"\u003eTCI C3923 138977-28-3 Capsazepine\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510o065745099\"\u003eTCI O0657 5987-82-6 Oxybuprocaine Hydrochloride\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan target saluran ion spesifik (natrium, kalsium, atau kalium) serta bentuk garamnya (hidroklorida atau basa bebas), karena keduanya menentukan kesesuaian dengan desain eksperimen elektrofisiologi. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Bioactive Small Molecules, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-bioactive-small-molecules-others\"\u003eBioactive Small Molecules (Others)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-receptor-agonists\"\u003eReceptor Agonists\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-polyamines-bioactive-small-molecules\"\u003ePolyamines [Bioactive Small Molecules]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-antioxidant-and-free-radical-scavengers-bioactive-small-molecules\"\u003eAntioxidant and Free Radical Scavengers [Bioactive Small Molecules]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-enzyme-activators-bioactive-small-molecules\"\u003eEnzyme Activators [Bioactive Small Molecules]\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-bioactive-small-molecules\"\u003eBioactive Small Molecules\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510b672713654","title":"TCI B6727 30484-77-6 Flunarizine Dihydrochloride","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI B6727 Flunarizine Dihydrochloride (CAS 30484-77-6) is a diphenylpiperazine-class calcium channel blocker supplied as a pharmaceutical research reagent for experimental use. Researchers apply it as a pharmacological tool to probe calcium entry and related signalling pathways in cell and tissue models. The dihydrochloride salt form simplifies handling and stock solution preparation compared with the free base. AMI Scientific supplies the 25 g size, and the material is intended strictly for laboratory research rather than human, clinical, or therapeutic use.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAMJ et al. (2017). Flunarizine Dihydrochloride Nanoemulsion for Migraine Nasal Drug Delivery: Fabrication, Characterization and In Vitro Study. \u003cem\u003eDrug Delivery Letters\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.2174\/2210303106666160930113725\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.2174\/2210303106666160930113725\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eYelli et al. (2022). Development and validation of dissolution testing of Flunarizine dihydrochloride in tablet dosage form. \u003cem\u003ePharmacy Education\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.46542\/pe.2022.222.132137\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.46542\/pe.2022.222.132137\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eUpadhyay et al. (2018). Molecular recognition of flunarizine dihydrochloride and β-cyclodextrin inclusion complex by NMR and computational approaches. \u003cem\u003eChemistry Central Journal\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1186\/s13065-018-0395-4\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1186\/s13065-018-0395-4\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48085953970394,"sku":"TCI2510B672713654","price":2447000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6727.jpg?v=1768204519"},{"product_id":"tci2510o065745099","title":"TCI O0657 5987-82-6 Oxybuprocaine Hydrochloride","description":"\u003cp\u003e\u003cstrong\u003eOxybuprocaine Hydrochloride\u003c\/strong\u003e (CAS 5987-82-6) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eHPLC Grade\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C17H28N2O3.HCl\u003c\/li\u003e\n\u003cli\u003eCAS number: 5987-82-6\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(HPLC)(T)\u003c\/li\u003e\n\u003cli\u003eTCI product code: O0657\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e Benoxinate Hydrochloride; 2-(Diethylamino)ethyl 4-Amino-3-butoxybenzoate Hydrochloride\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48087924736218,"sku":"TCI2510O065745099","price":7422000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510O0657.jpg?v=1769057256"},{"product_id":"tci2510p261148465","title":"TCI P2611 130-86-9 Protopine","description":"\u003cp\u003e\u003cstrong\u003eProtopine\u003c\/strong\u003e (CAS 130-86-9) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eGC Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C20H19NO5\u003c\/li\u003e\n\u003cli\u003eCAS number: 130-86-9\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(GC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: P2611\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5mg","offer_id":48088133632218,"sku":"TCI2510P261148465","price":2503000.0,"currency_code":"IDR","in_stock":true},{"title":"25mg","offer_id":48088133664986,"sku":"TCI2510P261148466","price":8685000.0,"currency_code":"IDR","in_stock":true},{"title":"100mg","offer_id":48088133697754,"sku":"TCI2510P261148467","price":25942000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510P2611.jpg?v=1767136429"},{"product_id":"tci2510q011849451","title":"TCI Q0118 24003-58-5 QX 314 Bromide","description":"\u003cp\u003e\u003cstrong\u003eQX 314 Bromide\u003c\/strong\u003e (CAS 24003-58-5) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eHPLC Grade\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C16H27BrN2O\u003c\/li\u003e\n\u003cli\u003eCAS number: 24003-58-5\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(HPLC)(T)\u003c\/li\u003e\n\u003cli\u003eTCI product code: Q0118\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e 2-(2,6-Dimethylanilino)-N,N,N-triethyl-2-oxoethanaminium Bromide; 2-[(2,6-Dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethan-1-aminium Bromide\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"100mg","offer_id":48088195104986,"sku":"TCI2510Q011849451","price":2559000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510Q0118.jpg?v=1769057617"},{"product_id":"tci2510a36294461","title":"TCI A3629 333963-40-9 Lubiprostone","description":"\u003cp\u003e\u003cstrong\u003eLubiprostone\u003c\/strong\u003e (CAS 333963-40-9) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eReagent Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C20H32F2O5\u003c\/li\u003e\n\u003cli\u003eCAS number: 333963-40-9\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;93.0%(qNMR)\u003c\/li\u003e\n\u003cli\u003eTCI product code: A3629\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e 7-[(2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl]heptanoic Acid; (15R)-16,16-Difluoro-15-hydroxy-9-oxo-11alpha,12alpha-11,15-epoxyprostan-1-oic Acid\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25mg","offer_id":48085477261530,"sku":"TCI2510A36294461","price":7674000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510A3629.jpg?v=1767084609"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-channel-blockers.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}