{"title":"Chaotropic Agents","description":"\u003cp\u003e\u003cstrong\u003eChaotropic Agents\u003c\/strong\u003e — berisi senyawa kaotropik (chaotropic agent) yang mengganggu ikatan hidrogen dan interaksi hidrofobik dalam larutan air, sehingga mengubah struktur ikatan non-kovalen pada makromolekul. Senyawa seperti urea, tiourea, dan garam guanidinium umum dipakai untuk keperluan ini.\u003c\/p\u003e\u003cp\u003eUrea, Guanidine Hydrochloride, dan Guanidine Thiocyanate dipakai dalam biokimia protein untuk denaturasi terkontrol saat pelipatan ulang (refolding) protein rekombinan atau pelarutan badan inklusi (inclusion body). Guanidine Thiocyanate juga berperan penting dalam protokol ekstraksi RNA karena kemampuannya menonaktifkan aktivitas enzim RNase, sementara Thiourea kerap dipadukan dengan urea pada elektroforesis 2D untuk melarutkan protein membran yang sulit larut.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510u007756291\"\u003eTCI U0077 57-13-6 Urea [for Biochemical Research]\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510g019731806\"\u003eTCI G0197 50-01-1 Guanidine Hydrochloride [for Protein Research]\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t283554301\"\u003eTCI T2835 62-56-6 Thiourea [for Biochemical Research]\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510g036031992\"\u003eTCI G0360 593-84-0 Guanidine Thiocyanate [for Biochemical Research]\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan kemurnian tingkat biokimia (bebas RNase\/DNase untuk kerja asam nukleat), bentuk fisik seperti kristal atau larutan stok, serta konsentrasi molar yang dibutuhkan sesuai protokol denaturasi. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Denaturation, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-detergents-denaturation\"\u003eDetergents [Denaturation]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-pharmaceutical-research-reagents-for-experimental-use\"\u003ePharmaceutical Research Reagents (for Experimental Use)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-amino-acids\"\u003eAmino Acids\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-carbohydrates\"\u003eCarbohydrates\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-lipids\"\u003eLipids\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-antibiotics\"\u003eAntibiotics\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-denaturation\"\u003eDenaturation\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510g019731806","title":"TCI G0197 50-01-1 Guanidine Hydrochloride [for Protein Research]","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eGuanidine Hydrochloride TCI G0197 is a chemical compound widely used in molecular biology and biochemistry research. It serves as a powerful denaturant, capable of disrupting the secondary and tertiary structures of proteins, making it essential for various protein-related experiments. This compound is commonly employed in laboratory settings to denature proteins, facilitating their separation, structural analysis, or extraction from complex samples. Its role is critical in studies involving protein conformational changes and functional analysis.\u003c\/p\u003e\n\u003cp\u003eOne of the key attributes of Guanidine Hydrochloride is its chemical stability and high solubility in water, which makes it highly versatile for use in different research solutions. Its ability to inhibit specific enzymes also adds to its value in biochemical studies, allowing researchers to control enzymatic activity and study reaction mechanisms. Additionally, its non-toxic nature at typical usage levels ensures a safe working environment, making it a preferred choice for both academic and industrial laboratories.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, Guanidine Hydrochloride is frequently utilized in protein research and biochemical analysis. It is a common reagent in university and research institute settings, supporting studies on protein structure, denaturation processes, and method development. Its availability and reliability make it an important tool for advancing scientific research in the region.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eProtein Denaturation: Guanidine Hydrochloride is ideal for denaturing proteins, breaking down their secondary and tertiary structures to study their primary sequence and functional properties.\u003c\/li\u003e\n\u003cli\u003eEnzyme Inhibition Studies: Its ability to inhibit specific enzymes makes it useful in investigating enzyme mechanisms and regulatory pathways in biochemical processes.\u003c\/li\u003e\n\u003cli\u003eProtein Extraction: It is commonly used to aid in the extraction of proteins from complex biological samples, improving the efficiency of purification techniques.\u003c\/li\u003e\n\u003cli\u003eStructural Analysis: Researchers use it to analyze protein conformations and assess how environmental factors affect protein structure and function.\u003c\/li\u003e\n\u003cli\u003eMethod Development: It plays a key role in developing and optimizing denaturation protocols for various protein-related applications in biochemistry.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 50-01-1\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Biochemicals and Reagents \u0026gt; Denaturation\u003c\/li\u003e\n\u003cli\u003ePack sizes: Not specified\u003c\/li\u003e\n\u003cli\u003ePhysical form: Not specified\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from moisture and direct sunlight\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eGuanidine Hydrochloride should be stored in a cool, dry place, away from moisture and direct sunlight to maintain its chemical stability. It is recommended to use airtight containers to prevent contamination and degradation. While it is considered non-toxic at typical usage levels, standard laboratory safety precautions should still be followed, such as wearing gloves and eye protection when handling. It is important to ensure proper ventilation in the workspace to minimize exposure. The compound should not be mixed with incompatible substances, and appropriate waste disposal procedures should be followed to comply with safety regulations.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48087096918234,"sku":"TCI2510G019731806","price":648000.0,"currency_code":"IDR","in_stock":true},{"title":"100g","offer_id":48087096951002,"sku":"TCI2510G019731807","price":1546000.0,"currency_code":"IDR","in_stock":true},{"title":"500g","offer_id":48087096983770,"sku":"TCI2510G019731808","price":3908000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510G0197.jpg?v=1768819023"},{"product_id":"tci2510g036031992","title":"TCI G0360 593-84-0 Guanidine Thiocyanate [for Biochemical Research]","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eGuanidine Thiocyanate is a chemical compound widely used in biochemical research, particularly in protein denaturation processes. It plays a crucial role in laboratories by disrupting the secondary and tertiary structures of proteins, enabling efficient separation and analysis of biological components. This compound is commonly employed in RNA and DNA extraction procedures, where it helps in breaking down complex protein matrices. Its effectiveness in denaturation makes it an essential reagent for various molecular biology applications.\u003c\/p\u003e\n\u003cp\u003eOne of the key properties that make Guanidine Thiocyanate a preferred choice is its ability to lower the melting point of proteins and inhibit enzymatic activity. It is colorless, highly soluble in water, and chemically stable under specific conditions, which ensures consistent performance in laboratory settings. These characteristics allow it to function effectively across a range of reaction conditions, making it a versatile tool for researchers. Its stability and solubility also contribute to its reliability in different experimental protocols.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, Guanidine Thiocyanate is extensively used in biomedical, biotechnology, and analytical chemistry research. It is a vital component in the processing and analysis of biomolecules, especially in facilities focused on molecular biology and biochemistry. Its role in denaturation and protein separation supports a wide array of scientific investigations, making it a standard reagent in many research environments.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eRNA and DNA extraction where protein denaturation is required to isolate nucleic acids effectively.\u003c\/li\u003e\n\u003cli\u003eProtein separation from complex mixtures to facilitate purification and analysis in biochemical studies.\u003c\/li\u003e\n\u003cli\u003eDenaturation of proteins in analytical procedures to study structural changes and functional properties.\u003c\/li\u003e\n\u003cli\u003eBiochemical research involving the disruption of protein structures for molecular characterization.\u003c\/li\u003e\n\u003cli\u003eSample preparation for electrophoresis and other analytical techniques that require protein denaturation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 593-84-0\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Biochemicals and Reagents \u0026gt; Denaturation\u003c\/li\u003e\n\u003cli\u003ePack sizes: Available in various quantities as per standard laboratory reagent packaging\u003c\/li\u003e\n\u003cli\u003ePhysical form: Colorless liquid or solid, depending on concentration and formulation\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from direct sunlight and incompatible materials\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eGuanidine Thiocyanate should be stored in a cool, dry location, away from direct sunlight and incompatible substances. It is recommended to use sealed containers to prevent moisture absorption and contamination. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Proper ventilation is essential when working with this compound to minimize exposure risks. It is important to follow standard laboratory safety protocols to maintain a safe working environment. Always ensure that storage conditions are suitable for the specific form and concentration of the compound being used.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48087107436762,"sku":"TCI2510G036031992","price":507000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48087107469530,"sku":"TCI2510G036031993","price":732000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510G0360.jpg?v=1767115084"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-chaotropic-agents.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}