{"title":"Chemical Mediators","description":"\u003cp\u003e\u003cstrong\u003eChemical Mediators\u003c\/strong\u003e — mencakup senyawa endogen seperti tyramine, acetylcholine, dan serotonin yang berperan sebagai mediator kimiawi dalam komunikasi antarsel, transmisi sinyal saraf, serta respons fisiologis tubuh. Kelompok ini juga meliputi analog dan prekursornya yang lazim dipakai sebagai standar riset.\u003c\/p\u003e\u003cp\u003eChemical Mediators digunakan peneliti neurosains dan farmakologi untuk mempelajari jalur sinyal kolinergik dan serotonergik, memodelkan respons reseptor pada uji in vitro, serta menjadi senyawa pembanding dalam pengembangan metode analitik seperti HPLC dan ELISA. Senyawa ini juga berperan sebagai standar kalibrasi pada studi mekanisme inflamasi dan alergi.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510a0302442\"\u003eTCI A0302 51-67-2 Tyramine\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510h014632550\"\u003eTCI H0146 56-92-8 Histamine Dihydrochloride\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510a0084131\"\u003eTCI A0084 60-31-1 Acetylcholine Chloride\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510h014732553\"\u003eTCI H0147 51-74-1 Histamine Diphosphate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t049451370\"\u003eTCI T0494 10603-92-6 Trimethylvinylammonium Bromide\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510h014832556\"\u003eTCI H0148 4998-57-6 DL-Histidine\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510s037050192\"\u003eTCI S0370 153-98-0 Serotonin Hydrochloride\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510h014932558\"\u003eTCI H0149 71-00-1 L-Histidine\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan bentuk garam (hidroklorida, sulfat, atau bromida) yang memengaruhi kelarutan dan stabilitas larutan stok, serta tingkat kemurnian dan kondisi penyimpanan yang dibutuhkan untuk aplikasi analitik kuantitatif. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Immune System, Inflammation, Allergy Research, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-anti-inflammatory-ingredients-for-research-and-experimental-use\"\u003eAnti-inflammatory Ingredients (for Research and Experimental Use)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-anti-allergic-ingredients-for-research-and-experimental-use\"\u003eAnti-allergic Ingredients (for Research and Experimental Use)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-gaba-receptor-inhibitors\"\u003eGABA Receptor Inhibitors\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-nf-b-activation-inhibitors\"\u003eNF-κB Activation Inhibitors\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-nlrp3-inflammasome-inhibitors\"\u003eNLRP3 Inflammasome Inhibitors\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-metabolic-antagonists\"\u003eMetabolic Antagonists\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-immune-system-inflammation-allergy-research\"\u003eImmune System, Inflammation, Allergy Research\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510h014632550","title":"TCI H0146 56-92-8 Histamine Dihydrochloride","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eHistamine Dihydrochloride is the dihydrochloride salt form of histamine, a biogenic amine built around an imidazole ring that plays an important role in the immune system, allergic responses, and the regulation of gastric acid secretion. This product is supplied by TCI under catalogue code H0146 and carries CAS number 56-92-8. Converting the free base into its salt form yields a stable solid that is straightforward to weigh out and dissolves readily in water, making it considerably more practical to handle in routine laboratory work than the free base itself.\u003c\/p\u003e\n\u003cp\u003eThe properties that make this material a preferred choice begin with the stability of the salt form, which allows it to be stored and handled as a conventional solid reagent. Its high water solubility means stock solutions can be prepared quickly and reproducibly without recourse to organic co-solvents. Beyond its physical handling characteristics, the compound offers biological activity that has been very thoroughly characterised across the various histamine receptor subtypes, giving researchers a well-understood reference point. The imidazole ring within its structure also makes this compound an important representative of the nitrogen-containing heterocyclic building block class.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this material is typically used as an analytical reference compound, as an agonist in pharmacological receptor research, and as a positive control in testing related to allergic reactions. The availability of 1 g, 5 g, and 25 g pack sizes gives flexibility both to laboratories that need only small quantities of reference material and to those running repeated, routine testing programmes, so the pack can be matched to the actual consumption rate of the facility.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAnalytical reference standard preparation, where the stable, easily weighed salt form allows accurate reference solutions to be made up for comparison against sample results.\u003c\/li\u003e\n\u003cli\u003ePharmacological receptor research as an agonist, drawing on biological activity that is already very well characterised across the different histamine receptor subtypes studied.\u003c\/li\u003e\n\u003cli\u003ePositive control material in allergy-related testing, providing a known-active reference against which assay responses and method performance can be verified.\u003c\/li\u003e\n\u003cli\u003eHeterocyclic building block work in synthetic chemistry, since the imidazole ring makes it a representative example of nitrogen-containing heterocyclic structures.\u003c\/li\u003e\n\u003cli\u003eRoutine stock solution preparation for repeated assays, as the high water solubility lets laboratories prepare aqueous solutions quickly without additional solubilising agents.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI, catalogue code H0146\u003c\/li\u003e\n\u003cli\u003eCAS number: 56-92-8\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Building Blocks \u0026gt; Heterocyclic Building Blocks\u003c\/li\u003e\n\u003cli\u003ePack sizes: 1 g, 5 g, and 25 g\u003c\/li\u003e\n\u003cli\u003ePhysical form: solid (salt form of histamine), readily soluble in water\u003c\/li\u003e\n\u003cli\u003eStorage: keep in the tightly closed original container, protected from moisture\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the material in its original, tightly closed container in a cool, dry place away from moisture and direct sunlight, since the salt should be kept free-flowing and easy to weigh. Amber glass or the supplier's original packaging is suitable for storage, and prepared aqueous stock solutions should be kept in clearly labelled, sealed containers. Handle the powder in a well-ventilated area or fume hood to avoid inhaling dust, and wear gloves, safety glasses, and a laboratory coat when weighing or transferring. Because this compound is biologically active, avoid skin contact and ingestion, close the container promptly after use, and consult the supplier's safety data sheet before first use and for disposal guidance.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48087159275738,"sku":"TCI2510H014632550","price":536000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48087159308506,"sku":"TCI2510H014632551","price":1238000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48087159341274,"sku":"TCI2510H014632552","price":3796000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510H0146.jpg?v=1767115766"},{"product_id":"tci2510h014732553","title":"TCI H0147 51-74-1 Histamine Diphosphate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eHistamine Diphosphate (51-74-1), also known as TCI H0147, is a chemical compound widely used in laboratory settings for its versatile role in chemical reactions and molecular synthesis. As a key component in heterocyclic compounds, it plays a crucial role in organic and analytical chemistry research. Its unique chemical structure allows it to act as a proton donor or a pH regulator, making it indispensable in processes that require precise pH control. This compound is particularly valuable in the synthesis of complex molecules where maintaining optimal reaction conditions is essential.\u003c\/p\u003e\n\u003cp\u003eThe properties of Histamine Diphosphate that make it a preferred choice include its chemical stability under specific conditions and its solubility in water. These characteristics ensure that it remains effective without significant degradation during chemical reactions. Additionally, its ability to bind with metal ions enhances its utility in complex reactions and quantitative analysis. The compound’s stability and reactivity make it a reliable reagent in various experimental setups, contributing to the accuracy and reproducibility of laboratory results.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, Histamine Diphosphate is commonly used in organic chemistry research, biological compound analysis, and product development. Its role in facilitating controlled chemical reactions and its compatibility with various experimental conditions make it a staple in both academic and industrial research environments. Its widespread application underscores its importance as a fundamental building block in chemical synthesis and analytical processes.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eOrganic synthesis applications benefit from Histamine Diphosphate’s ability to regulate pH and act as a proton donor, enhancing reaction efficiency in complex molecule creation.\u003c\/li\u003e\n\u003cli\u003eAnalytical chemistry relies on this compound for its capacity to bind metal ions, aiding in the detection and quantification of trace elements in samples.\u003c\/li\u003e\n\u003cli\u003eBiochemical research utilizes Histamine Diphosphate due to its role in maintaining pH stability during enzyme assays and protein studies.\u003c\/li\u003e\n\u003cli\u003ePharmaceutical development incorporates this compound in the synthesis of drug molecules that require precise pH control during formulation.\u003c\/li\u003e\n\u003cli\u003eEnvironmental analysis employs Histamine Diphosphate to monitor and control pH levels in samples, ensuring accurate data collection in water and soil testing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 51-74-1\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Building Blocks \u0026gt; Heterocyclic Building Blocks\u003c\/li\u003e\n\u003cli\u003ePack sizes: Not specified in the provided data\u003c\/li\u003e\n\u003cli\u003ePhysical form: Not specified in the provided data\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from moisture and direct sunlight\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eHistamine Diphosphate should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to keep the compound in a sealed container to avoid exposure to moisture and air, which can affect its performance in reactions. While the physical form is not specified, it is advisable to use appropriate containers that are resistant to chemical reactions and ensure safe handling. Laboratory personnel should always follow standard safety protocols when working with this compound, including wearing protective gloves and goggles. Proper storage conditions are essential to ensure the compound remains effective and safe for use in various experimental applications.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48275633602778,"sku":"TCI2510H014732553","price":1069000.0,"currency_code":"IDR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510H0147.jpg?v=1767115770"},{"product_id":"tci2510h014832556","title":"TCI H0148 4998-57-6 DL-Histidine","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eDL-Histidine is the racemic form of the amino acid histidine, consisting of an equal mixture of the D and L enantiomers and carrying the characteristic imidazole side chain. It belongs to the group of semi-essential amino acids and participates in protein synthesis, in the enzymatic formation of histamine, and in the regulation of acid-base balance within the cell. In the TCI catalogue this product is listed under the code H0148 and is positioned within the peptide chemistry product line. In the laboratory, DL-Histidine is used as a raw material for growth media, as a component of biological buffers, as a metal-chelating reagent, and as a comparison compound in studies of enzyme selectivity toward stereochemical configuration.\u003c\/p\u003e\n\u003cp\u003eThe characteristic that makes this compound a frequent choice is the presence of the imidazole ring, whose pKa value lies close to physiological pH. Because of this, histidine is able to accept and release protons across the pH range at which biological systems operate, allowing it to act as an effective natural buffering species. The same imidazole group also confers the ability to bind transition metal ions such as nickel, copper, and zinc, a property that forms the basis of various protein purification techniques founded on metal affinity. As a racemic form, DL-Histidine is generally more economical than the pure L form.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, DL-Histidine is typically encountered in biochemistry, microbiology, and molecular biology work. It is drawn on when growth media must be prepared or supplemented, when buffer systems need a component that is active near physiological pH, and when metal-binding behaviour is being examined. Its role as a reference compound in stereoselectivity work also makes it useful in teaching laboratories and in research groups that compare enzyme responses toward the D and L configurations of the same amino acid.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePreparation of microbial growth media: DL-Histidine serves as an amino acid raw material that supplies the nitrogen and carbon skeleton required for culture formulation and supplementation work.\u003c\/li\u003e\n\u003cli\u003eFormulation of biological buffer systems: the imidazole side chain has a pKa close to physiological pH, so the compound buffers effectively across the working range of biological experiments.\u003c\/li\u003e\n\u003cli\u003eMetal chelation reagent: the imidazole group binds transition metal ions such as nickel, copper, and zinc, making the compound useful wherever controlled metal coordination is required.\u003c\/li\u003e\n\u003cli\u003eMetal-affinity protein purification studies: the same imidazole-metal interaction underlies affinity-based purification techniques, so this amino acid supports method development and elution experiments.\u003c\/li\u003e\n\u003cli\u003eEnzyme stereoselectivity comparison: as a racemate containing both D and L enantiomers, it acts as a reference material when testing how enzymes discriminate between stereochemical configurations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 4998-57-6\u003c\/li\u003e\n\u003cli\u003eCatalogue code: H0148\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Peptide Chemistry\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in the standard catalogue pack sizes offered for this item; please confirm the required quantity when ordering\u003c\/li\u003e\n\u003cli\u003eStorage: store in a closed original container under the conditions stated on the product label\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore DL-Histidine in its original tightly closed container, kept in a cool, dry, and well-ventilated area away from moisture and direct sunlight, and follow any storage condition printed on the product label. Suitable containers include the supplied packaging or a clean, well-sealed glass or chemically compatible plastic vessel with a clear label. Handle the material in a clean working area, use standard laboratory protective equipment such as gloves, safety glasses, and a laboratory coat, and avoid generating or inhaling dust. Use clean, dry spatulas when weighing to prevent contamination of the remaining stock, close the container immediately after use, and consult the manufacturer safety data sheet before handling.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48087159603418,"sku":"TCI2510H014832556","price":676000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48087159636186,"sku":"TCI2510H014832557","price":4751000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510H0148.jpg?v=1768197411"},{"product_id":"tci2510h014932558","title":"TCI H0149 71-00-1 L-Histidine","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eL-Histidine is a proteinogenic amino acid that naturally forms part of the proteins of living organisms, classified as essential for children and semi-essential for adults. Its molecular structure carries an imidazole side chain, which makes it one of the most chemically versatile of the amino acids. In the TCI catalogue this product is listed under the code H0149 and is grouped within the conjugation chemistry and click chemistry product lines, reflecting its role as a reactive and coordinating building block in modern biochemical work.\u003c\/p\u003e\n\u003cp\u003eThe main attraction of this compound lies in its imidazole ring, which can shift protonation state around physiological pH and therefore acts both as a buffering group and as an acid-base catalyst at the active sites of many enzymes. Its ability to form strong coordination bonds with nickel and cobalt ions underpins the purification of histidine-tagged proteins by immobilised metal affinity chromatography, one of the most widely used methods in modern molecular biology. As a pure L-enantiomer, the material suits experiments that demand optical purity.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, L-Histidine is used as a component of culture media formulations, as a constituent of buffer systems, as a metal-chelating ligand, and as a selective attachment point in a range of biomolecule conjugation and protein engineering strategies. These roles place it in university biochemistry teaching laboratories, molecular biology research groups, biotechnology facilities, and analytical laboratories preparing reference solutions and working media for routine and developmental work.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eCell and microbial culture media preparation — supplied as a defined amino acid component so that media composition remains controlled and reproducible across repeated culture batches.\u003c\/li\u003e\n\u003cli\u003eBuffer system formulation — the imidazole side chain changes protonation state near physiological pH, allowing the compound to stabilise solution pH in biochemical work.\u003c\/li\u003e\n\u003cli\u003eMetal-chelating ligand chemistry — the side chain coordinates strongly with transition metal ions, making it useful wherever a defined amino acid chelator is required.\u003c\/li\u003e\n\u003cli\u003eImmobilised metal affinity chromatography studies — its strong nickel and cobalt coordination is the chemical basis of histidine-tagged protein purification, a standard molecular biology technique.\u003c\/li\u003e\n\u003cli\u003eBioconjugation and protein engineering — serves as a selective attachment point in conjugation and click chemistry strategies for building modified biomolecules and protein constructs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI (catalogue code H0149)\u003c\/li\u003e\n\u003cli\u003eCAS number: 71-00-1\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Conjugation Chemistry \/ Click Chemistry\u003c\/li\u003e\n\u003cli\u003eChemical identity: L-Histidine, the pure L-enantiomer, suitable for work requiring optical purity\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in the pack sizes listed in the TCI catalogue for this item\u003c\/li\u003e\n\u003cli\u003eStorage: store according to the conditions stated on the manufacturer's label and safety data sheet\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eKeep the container tightly closed in a cool, dry, well-ventilated area, away from moisture, direct sunlight, and incompatible materials, and follow the storage conditions given on the manufacturer's label and safety data sheet. Original supplier packaging or clean, tightly sealed glass or chemically resistant plastic containers with clear labelling are appropriate. Handle with standard laboratory personal protective equipment, including a laboratory coat, safety glasses, and gloves, and weigh out portions on a clean balance to avoid contaminating the bulk stock. Use clean, dry spatulas, close the container promptly after dispensing, and consult the safety data sheet before first use and before disposal.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48087159931098,"sku":"TCI2510H014932558","price":957000.0,"currency_code":"IDR","in_stock":true},{"title":"250g","offer_id":48087159963866,"sku":"TCI2510H014932559","price":4189000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48087159996634,"sku":"TCI2604H0149235","price":648000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510H0149.jpg?v=1767115774"},{"product_id":"tci2510h015032560","title":"TCI H0150 5934-29-2 L-Histidine Hydrochloride Monohydrate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eL-Histidine Hydrochloride Monohydrate is the hydrochloride salt form of the amino acid L-histidine, crystallised with one molecule of water. This salt modification was developed to improve solubility behaviour and ease of handling without altering the molecular framework or the stereochemical configuration of the parent amino acid. In the TCI catalogue the product carries the code H0150 and is grouped within the peptide chemistry product line. In the laboratory the material is widely used for preparing histidine buffers, as a component of cell culture media, as a formulation ingredient in model therapeutic protein preparations, and as a reagent in coordination chemistry research and protein purification work.\u003c\/p\u003e\n\u003cp\u003eThe advantage of the hydrochloride monohydrate form lies in its water solubility, which is considerably better than that of free histidine, so that high-concentration solutions can be prepared quickly without excessive heating or complicated pH adjustment. The defined content of water of crystallisation gives the compound a consistent molecular weight, which makes molarity calculations more reliable. The solid itself is relatively stable, does not cake easily, and is straightforward to weigh out. The buffering character contributed by the imidazole ring is fully retained, making this form a popular choice for biopharmaceutical formulation buffers.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories these characteristics matter in practical daily work. Analysts preparing histidine buffer systems, culture media, or protein formulation studies benefit from a material that dissolves readily at ambient conditions and weighs reproducibly, since buffer preparation is often repeated across many batches. The catalogue code H0150 and the peptide chemistry classification make the item straightforward to identify and reorder for teams running routine protein and buffer preparation work.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHistidine buffer preparation — the retained imidazole ring buffering character and high water solubility allow buffer solutions to be made up rapidly without excessive heating or complicated pH adjustment.\u003c\/li\u003e\n\u003cli\u003eCell culture media formulation — the material serves as a histidine source component in culture media, where its consistent molecular weight supports reliable molarity calculations during media makeup.\u003c\/li\u003e\n\u003cli\u003eModel therapeutic protein formulation — the hydrochloride monohydrate form is a popular choice for biopharmaceutical formulation buffers because its buffering behaviour and dissolution properties are retained from the parent amino acid.\u003c\/li\u003e\n\u003cli\u003eCoordination chemistry research — L-histidine's molecular framework and stereochemical configuration are unchanged by the salt modification, making the compound a suitable reagent for coordination studies.\u003c\/li\u003e\n\u003cli\u003eProtein purification work — the material is used as a reagent in purification procedures, where rapid preparation of high-concentration solutions without excessive heating is a practical benefit.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI, catalogue code H0150\u003c\/li\u003e\n\u003cli\u003eCAS number: 5934-29-2\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Peptide Chemistry\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in the pack sizes listed for this catalogue item\u003c\/li\u003e\n\u003cli\u003ePhysical form: crystalline solid containing one molecule of water of crystallisation; relatively stable, not prone to caking, and easy to weigh\u003c\/li\u003e\n\u003cli\u003eStorage note: store the container closed and protected from moisture so that the defined water of crystallisation content and the reliability of molarity calculations are preserved\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the product in its original tightly closed container, kept dry and protected from moisture uptake, since the defined content of water of crystallisation is what makes the molecular weight consistent and molarity calculations dependable. Glass or chemically compatible plastic containers with well-sealing closures are suitable, and containers should be reclosed promptly after each weighing. Handle the solid in a clean, dry working area using dedicated dry spatulas to avoid cross-contamination between batches. General laboratory precautions apply: wear a laboratory coat, safety glasses, and suitable gloves, avoid raising dust during transfer, and label all prepared solutions clearly with the concentration and preparation date. 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