{"title":"Chiral Organocatalysts (Other)","description":"\u003cp\u003e\u003cstrong\u003eChiral Organocatalysts (Other)\u003c\/strong\u003e — menghimpun katalis organik kiral dengan struktur khas seperti IDPi, oksazaborolidin, dan senyawa fosfina\/amida asimetris yang tidak termasuk kelas organokatalis kiral utama lainnya. Kategori ini melengkapi koleksi katalis, ligan, dan reagen kiral untuk sintesis asimetris.\u003c\/p\u003e\u003cp\u003eKatalis seperti Tf-IDPi dan turunan oksazaborolidin dipakai kimiawan sintesis asimetris untuk mengarahkan stereoselektivitas pada reaksi seperti reduksi, adisi Mukaiyama, atau reaksi Diels-Alder terkatalisis. Katalis berbasis fosfina atau amida bis-mesitil juga digunakan dalam reaksi pembentukan ikatan C-C dan C-X yang memerlukan kontrol enansioselektif tinggi.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510t293754421\"\u003eTCI T2937 1264520-63-9 O-TBDPS-D-Thr-N-Boc-L-tert-Leu-Diphenylphosphine\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b694613821\"\u003eTCI B6946 148461-16-9 (S)-4-(tert-Butyl)-2-[2-(diphenylphosphaneyl)phenyl]-4,5-dihydrooxazole\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510n136044248\"\u003eTCI N1360 2073168-81-5 (S,S)-2-Naphthyl-Tf-IDPi\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b704413882\"\u003eTCI B7044 (R,R)-4-tert-Butylphenyl-Tf-IDPi\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510n135944247\"\u003eTCI N1359 2016814-96-1 (R,R)-2-Naphthyl-Tf-IDPi\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b704513883\"\u003eTCI B7045 2073168-80-4 (S,S)-4-tert-Butylphenyl-Tf-IDPi\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510i112236487\"\u003eTCI I1122 1399008-27-5 N,N'-[(2S,2'S)-[(2-Iodo-1,3-phenylene)bis(oxy)]bis(propane-2,1-diyl)]bis(mesitylamide)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510i080136066\"\u003eTCI I0801 850661-66-4 (S)-4-Isopropyl-3-(1-naphthylmethyl)-2,5,5-triphenyl-1,3,2-oxazaborolidine (ca. 6% in Toluene, ca. 0.1mol\/L)\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan konfigurasi absolut (R atau S) katalis serta bentuk fisiknya, termasuk larutan siap pakai dengan konsentrasi molar tertentu, agar sesuai dengan protokol reaksi asimetris yang direncanakan. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Chiral Catalysts, Chiral Ligands, Chiral Reagents, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-chiral-ligands-other\"\u003eChiral Ligands (Other)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-chiral-catalysts-other\"\u003eChiral Catalysts (Other)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-chiral-catalysts-chiral-ligands-chiral-reagents\"\u003eChiral Catalysts, Chiral Ligands, Chiral Reagents\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510i080136066","title":"TCI I0801 850661-66-4 (S)-4-Isopropyl-3-(1-naphthylmethyl)-2,5,5-triphenyl-1,3,2-oxazaborolidine (ca. 6% in Toluene, ca. 0.1mol\/L)","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI I0801, (S)-4-Isopropyl-3-(1-naphthylmethyl)-2,5,5-triphenyl-1,3,2-oxazaborolidine, CAS number 850661-66-4, is a chiral catalyst of the oxazaborolidine class supplied as a ready-to-use solution in toluene at approximately 6% concentration, corresponding to roughly 0.1 mol per litre. The molecule carries a boron centre embedded in an oxazaborolidine ring containing both nitrogen and oxygen, surrounded by phenyl groups and a bulky naphthylmethyl substituent. In the laboratory this class of catalyst acts as a chiral Lewis acid that activates carbonyl substrates or dienophiles while simultaneously steering the reaction towards a single enantiomer.\u003c\/p\u003e\n\u003cp\u003eThe property that makes this reagent a preferred choice is its presentation as a solution of defined concentration. Oxazaborolidine catalysts are highly sensitive to moisture and to air, so supplying the material dissolved in toluene removes the inconvenience of weighing a hygroscopic solid inside a glove box and allows catalytic doses to be withdrawn simply with a gas-tight syringe. The aromatic groups stacked around the boron centre create a tightly defined chiral pocket, so one face of the substrate is decisively blocked and the product is formed with enantiomeric excess.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories a reagent of this type belongs to research groups and analytical or synthetic units working on asymmetric synthesis, typically in university chemistry departments, pharmaceutical development laboratories and contract research settings where a single enantiomer of an intermediate must be prepared. The solution format suits laboratories that handle air-sensitive chemistry with Schlenk lines or inert-atmosphere manifolds rather than full glove-box infrastructure, and makes small-scale catalytic work practical.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eEnantioselective reduction of prochiral ketones: the chiral boron centre coordinates and activates the carbonyl group while the surrounding aryl framework blocks one face, so the resulting secondary alcohol is obtained with enantiomeric excess rather than as a racemate.\u003c\/li\u003e\n\u003cli\u003eAsymmetric Diels-Alder cycloadditions: acting as a chiral Lewis acid, the catalyst activates the dienophile and biases the approach of the diene, giving cycloadducts whose absolute configuration is controlled by the catalyst rather than by the substrate.\u003c\/li\u003e\n\u003cli\u003ePreparation of single-enantiomer pharmaceutical intermediates: research groups use catalytic quantities of this reagent to install a defined stereocentre early in a synthetic route, avoiding the material losses associated with resolving a racemic mixture later.\u003c\/li\u003e\n\u003cli\u003eMethodology and catalyst screening studies: because the reagent arrives at a known concentration of about 0.1 mol per litre, catalyst loadings can be varied accurately by syringe volume, which makes systematic optimisation experiments straightforward and reproducible.\u003c\/li\u003e\n\u003cli\u003eAir-sensitive small-scale synthesis under inert atmosphere: the toluene solution can be transferred by gas-tight syringe through a septum into a Schlenk flask, so the moisture-sensitive catalyst never has to be handled as an open solid.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI (Tokyo Chemical Industry)\u003c\/li\u003e\n\u003cli\u003eCAS number: 850661-66-4\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Asymmetric Synthesis \u0026gt; Chiral Catalysts, Chiral Ligands, Chiral Reagents\u003c\/li\u003e\n\u003cli\u003ePack sizes: supplied in TCI standard solution pack sizes; please confirm the available size when ordering\u003c\/li\u003e\n\u003cli\u003ePhysical form: solution in toluene, approximately 6% (ca. 0.1 mol\/L)\u003c\/li\u003e\n\u003cli\u003eStorage note: moisture-sensitive and air-sensitive; keep the container tightly sealed under inert gas\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the sealed bottle in a cool, dry place away from direct sunlight, ignition sources and oxidising agents, and follow the storage temperature stated on the manufacturer's label and safety data sheet. Keep the container under an inert gas blanket and close it immediately after each withdrawal, since both the catalyst and the toluene solvent are sensitive to moisture and air. Withdraw aliquots with a dry, gas-tight syringe through the septum rather than pouring, and keep all glassware oven-dried. Handle the solution in a fume hood because toluene is a flammable and volatile solvent, and wear safety glasses, a laboratory coat and solvent-resistant gloves. Ground containers when transferring larger volumes, keep a suitable fire extinguisher accessible, and dispose of residues as halogen-free organic solvent waste in line with institutional procedures.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"10mL","offer_id":48087417585882,"sku":"TCI2510I080136066","price":3610000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510I0801.jpg?v=1767120328"},{"product_id":"tci2510i080736073","title":"TCI I0807 1226896-38-3 (R,R)-2-Iodo-1,3-bis[1-(mesitylcarbamoyl)ethoxy]benzene","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI I0807 (R,R)-2-Iodo-1,3-bis[1-(mesitylcarbamoyl)ethoxy]benzene, CAS number 1226896-38-3, is a chiral aryl iodide designed to serve as a pre-catalyst for oxidative transformations based on hypervalent iodine chemistry. Structurally, the molecule consists of a benzene ring bearing an iodine atom at the central position, flanked by two ether arms that each carry a mesityl amide group in the (R,R) configuration. In the laboratory, the compound is activated in situ by a suitable oxidant, raising the iodine atom to a higher oxidation state and generating a chiral hypervalent iodine species capable of transferring oxygen or functional groups to a substrate enantioselectively.\u003c\/p\u003e\n\u003cp\u003eThe properties that make this compound a preferred choice begin with its symmetric and rigid scaffold design. The two identical flanking arms create a symmetric chiral environment on both sides of the iodine centre, so the orientation of an incoming substrate can be controlled decisively. The amide groups act both as hydrogen-bond donors and as stabilising elements through intramolecular coordination to the hypervalent iodine centre, which makes the active species more robust and raises the selectivity obtained. The bulky mesityl groups add further steric shielding around the reaction centre, reinforcing facial discrimination during the stereo-determining step.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this reagent is typically encountered in university and institutional research groups working on asymmetric synthesis, particularly those developing metal-free enantioselective oxidation methods. It is used on small research scales, where the catalyst is generated in situ and screened against a range of oxidants, solvents and substrates. Groups pursuing chiral building blocks for pharmaceutical or natural-product targets use it as part of methodology development and catalyst comparison studies.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eEnantioselective oxidative transformations — the compound is activated in situ to a chiral hypervalent iodine species that transfers oxygen or functional groups to substrates with facial control from the (R,R) scaffold.\u003c\/li\u003e\n\u003cli\u003eMetal-free asymmetric catalysis method development — researchers avoiding transition metals use this organocatalytic aryl iodide because the chiral information resides entirely in the organic backbone rather than a metal centre.\u003c\/li\u003e\n\u003cli\u003eChiral catalyst screening studies — the defined (R,R) configuration and symmetric two-armed design make it a useful benchmark entry when comparing catalyst scaffolds for enantioselectivity in oxidation reactions.\u003c\/li\u003e\n\u003cli\u003ePreparation of enantiomerically enriched building blocks — reactions catalysed by this reagent deliver stereodefined products suited to downstream elaboration toward pharmaceutical intermediates and natural-product fragments in research-scale work.\u003c\/li\u003e\n\u003cli\u003eMechanistic and structure-activity investigations — the amide hydrogen-bond donors and bulky mesityl groups provide clear structural handles for studying how coordination and steric bulk govern selectivity outcomes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI (Tokyo Chemical Industry)\u003c\/li\u003e\n\u003cli\u003eCAS number: 1226896-38-3\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Asymmetric Synthesis \u0026gt; Chiral Catalysts, Chiral Ligands, Chiral Reagents\u003c\/li\u003e\n\u003cli\u003eChemical name: (R,R)-2-Iodo-1,3-bis[1-(mesitylcarbamoyl)ethoxy]benzene; product code I0807\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in research-scale catalogue pack sizes; please refer to the current TCI listing for options\u003c\/li\u003e\n\u003cli\u003eStorage: keep in a cool, dry place in the original tightly closed container, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the reagent in its original tightly closed container in a cool, dry and well-ventilated place, away from light, moisture and oxidising agents. Amber glass or the supplier's original packaging is suitable; keep the container sealed when not in use to prevent moisture uptake and to preserve the integrity of the chiral scaffold. Handle the material in a fume hood using gloves, safety glasses and a laboratory coat, and avoid generating dust during weighing. Transfer with clean, dry spatulas and glassware, close the container promptly after use, and dispose of residues and contaminated consumables through the laboratory's chemical waste procedure. Always consult the supplier safety data sheet before first use.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"200mg","offer_id":48087418142938,"sku":"TCI2510I080736073","price":1591000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510I0807.jpg?v=1767120340"},{"product_id":"tci2510i112236487","title":"TCI I1122 1399008-27-5 N,N'-[(2S,2'S)-[(2-Iodo-1,3-phenylene)bis(oxy)]bis(propane-2,1-diyl)]bis(mesitylamide)","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI I1122 1399008-27-5 is a complex chemical compound used in asymmetric synthesis, playing a vital role in laboratories that require precise control over stereochemistry. This chiral catalyst or ligand is essential for producing compounds with specific asymmetric structures, which are critical in pharmaceutical and organic chemistry research. Its unique molecular structure allows it to direct reactions toward the desired product, making it a valuable tool for researchers aiming to achieve high-purity synthetic outcomes.\u003c\/p\u003e\n\u003cp\u003eThe compound's stability under specific conditions and its ability to enhance reaction efficiency make it a preferred choice in modern chemical laboratories. Its complex molecular architecture enables it to interact effectively with various substrates, facilitating the synthesis of chiral compounds with high selectivity. This stability ensures that it remains effective across different experimental setups, providing consistent results. Its reliability and performance in controlled environments further solidify its position as a key reagent in asymmetric synthesis.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this compound is widely used by chemists engaged in asymmetric synthesis, particularly in research related to drug development, organic compounds, and complex molecules. Its availability and adherence to international quality standards make it a trusted choice for researchers seeking reliable and high-quality reagents. The compound's versatility and effectiveness in achieving specific stereochemical outcomes make it an essential component in many chemical research projects.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAsymmetric synthesis for the production of specific drug compounds requiring precise stereochemical control.\u003c\/li\u003e\n\u003cli\u003eOrganic chemistry research focused on the development of chiral molecules with high enantiomeric purity.\u003c\/li\u003e\n\u003cli\u003eAdvanced chemical reactions that demand controlled stereoselectivity and efficient catalytic activity.\u003c\/li\u003e\n\u003cli\u003eSynthesis of complex organic structures where chiral reagents are necessary for achieving desired product configurations.\u003c\/li\u003e\n\u003cli\u003ePharmaceutical research involving the creation of compounds with specific spatial arrangements for therapeutic applications.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 1399008-27-5\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Asymmetric Synthesis \u0026gt; Chiral Catalysts, Chiral Ligands, Chiral Reagents\u003c\/li\u003e\n\u003cli\u003ePack sizes: Not specified in the provided data\u003c\/li\u003e\n\u003cli\u003ePhysical form: Not specified in the provided data\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from moisture and direct sunlight\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eThis compound should be stored in a cool, dry environment to maintain its chemical stability and effectiveness. It is recommended to keep it in a sealed container to prevent exposure to moisture and air, which could potentially degrade its properties. Due to its complex molecular structure, it is important to handle it with care to avoid contamination. Laboratory personnel should ensure that the storage area is well-ventilated and free from sources of heat or direct light. Proper labeling of containers is essential to ensure safe handling and prevent accidental use. General laboratory precautions include wearing appropriate personal protective equipment when handling the compound to minimize any potential risks.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"200mg","offer_id":48087441735898,"sku":"TCI2510I112236487","price":4645000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510I1122.jpg?v=1767120807"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-chiral-organocatalysts-other.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}