{"title":"Cyanation [Synthetic Reagents]","description":"\u003cp\u003e\u003cstrong\u003eCyanation [Synthetic Reagents]\u003c\/strong\u003e — berisi reagen pembawa gugus sianida atau isosianida yang digunakan untuk membentuk ikatan karbon-nitrogen non-halogen dalam sintesis organik. Golongan ini berperan sebagai sumber gugus nitril atau isosianida pada berbagai transformasi kimia.\u003c\/p\u003e\u003cp\u003eReagen sianasi seperti trimetilsilil sianida atau tert-butil isosianida digunakan dalam reaksi adisi ke karbonil, reaksi Passerini dan Ugi, serta pembentukan senyawa heterosiklik pada sintesis organik dan pengembangan obat. Kimiawan sintesis memanfaatkannya untuk memperkenalkan gugus nitril sebagai prekursor asam karboksilat, amina, atau amida.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510b12746490\"\u003eTCI B1274 7188-38-7 tert-Butyl Isocyanide\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c044114561\"\u003eTCI C0441 105-56-6 Ethyl Cyanoacetate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t104652058\"\u003eTCI T1046 36635-61-7 p-Toluenesulfonylmethyl Isocyanide\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c124215716\"\u003eTCI C1242 2942-58-7 Diethyl Cyanophosphonate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t099051977\"\u003eTCI T0990 7677-24-9 Trimethylsilyl Cyanide\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c195216562\"\u003eTCI C1952 544-92-3 Copper(I) Cyanide\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t019850957\"\u003eTCI T0198 3012-37-1 Benzyl Thiocyanate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c234817105\"\u003eTCI C2348 59016-56-7 1-Cyano-4-(dimethylamino)pyridinium Tetrafluoroborate\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan kemurnian, kondisi penyimpanan anhidrat, dan reaktivitas spesifik tiap reagen terhadap elektrofil sasaran sebelum digunakan dalam reaksi multikomponen. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah C-X(Non-Halogen) Bond Formation [Synthetic Reagents], sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-c-h-bond-activation-reaction-synthetic-reagents\"\u003eC-H Bond Activation Reaction [Synthetic Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-formylation-synthetic-reagents\"\u003eFormylation [Synthetic Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-phosphorylation-synthetic-reagents\"\u003ePhosphorylation [Synthetic Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-mitsunobu-reaction-synthetic-reagents\"\u003eMitsunobu Reaction [Synthetic Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-vinylation-synthetic-reagents\"\u003eVinylation [Synthetic Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-amination-synthetic-reagents\"\u003eAmination [Synthetic Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-c-x-non-halogen-bond-formation-synthetic-reagents\"\u003eC-X(Non-Halogen) Bond Formation [Synthetic Reagents]\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510c044114561","title":"TCI C0441 105-56-6 Ethyl Cyanoacetate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C0441 Ethyl Cyanoacetate (CAS 105-56-6) is one of the most widely used active methylene reagents in synthetic organic chemistry. Its acidic methylene position readily forms carbon nucleophiles for Knoevenagel condensations, alkylations, and Michael additions. It is also the standard starting material for the Gewald reaction and for the synthesis of pyrazolones, substituted pyridines, and other nitrogen heterocycles. The liquid should be dispensed in a fume hood with gloves and eye protection and stored tightly closed in a cool, dry, well-ventilated place.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHoelz (2011). Ethyl cyanoacetate (CAS No. 105-56-6). \u003cem\u003eRevista Virtual de Química\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.5935\/1984-6835.20110025\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.5935\/1984-6835.20110025\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSemmes et al. (2015). Arylation of diethyl malonate and ethyl cyanoacetate catalyzed by palladium\/di-tert-butylneopentylphosphine. \u003cem\u003eTetrahedron Letters\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1016\/j.tetlet.2015.01.072\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1016\/j.tetlet.2015.01.072\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBaku State University et al. (2023). SYNTHESIS BASED ON ETHYL CYANOACETATE. \u003cem\u003eChemical Problems\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.32737\/2221-8688-2023-4-323-330\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.32737\/2221-8688-2023-4-323-330\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48085998829786,"sku":"TCI2510C044114561","price":507000.0,"currency_code":"IDR","in_stock":true},{"title":"500g","offer_id":48085998862554,"sku":"TCI2510C044114562","price":1097000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C0441.jpg?v=1767095243"},{"product_id":"tci2510c124215716","title":"TCI C1242 2942-58-7 Diethyl Cyanophosphonate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1242 Diethyl Cyanophosphonate (DEPC) is a well-established coupling reagent for activating carboxylic acids toward amide and ester bond formation. It is frequently applied in peptide synthesis, where it offers effective coupling under comparatively mild conditions. The reagent is highly toxic and moisture-sensitive, and hydrolysis can release extremely hazardous gas, so it must be handled only by trained personnel in a fume hood. Available in 5 g and 25 g packs, it must be stored, used, and disposed of strictly in accordance with the official TCI safety data sheet.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eGUZMAN et al. (1997). ChemInform Abstract: A Convenient Method for the Phosphorylation of Phenols with Diethyl Cyanophosphonate.. \u003cem\u003eChemInform\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1002\/chin.199747196\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1002\/chin.199747196\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eGuzmán et al. (1997). A Convenient Method for the Phosphorylation of Phenols with Diethyl Cyanophosphonate. \u003cem\u003eSynthetic Communications\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1080\/00397919708005008\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1080\/00397919708005008\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDemir et al. (2009). Cyanide Ion Promoted Addition of Acylphosphonates to Diethyl Cyanophosphonate: Synthesis of Phosphonocyanohydrin O-Phosphates. \u003cem\u003eSynthesis\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1055\/s-0029-1216634\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1055\/s-0029-1216634\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086058598618,"sku":"TCI2510C124215716","price":1799000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086058631386,"sku":"TCI2510C124215717","price":5904000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1242.jpg?v=1768204586"},{"product_id":"tci2510d551426430","title":"TCI D5514 7321-55-3 Dimethylmalononitrile","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eDimethylmalononitrile (DMN), with the CAS number 7321-55-3, is a synthetic reagent widely used in organic chemistry for the formation of carbon-carbon bonds. This compound features a central carbon atom bonded to two nitrile groups, enabling it to participate in a variety of chemical reactions. Its unique structure makes it a valuable tool in the synthesis of complex organic molecules. In laboratory settings, DMN plays a crucial role in advancing research in both academic and industrial environments. Its versatility and reactivity make it an essential component in modern synthetic chemistry.\u003c\/p\u003e\n\u003cp\u003eDMN is known for its stability under controlled conditions, yet it exhibits high reactivity when exposed to elevated temperatures or humidity. This reactivity is advantageous in reactions requiring high selectivity and efficiency, such as Michael additions and alkylation processes. Its ability to undergo various chemical transformations makes it a preferred choice for chemists seeking reliable and effective reagents. The solid form of DMN also simplifies handling and processing, making it ideal for use in laboratory environments that require precision and consistency.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, DMN is commonly used in organic chemistry research, particularly in pharmaceutical and material science applications. Its role in synthesizing heterocyclic compounds and other complex structures has made it an essential reagent for researchers. The demand for high-quality synthetic reagents has further solidified DMN’s position as a key component in ongoing scientific investigations. Its availability and performance make it a reliable choice for laboratories focused on innovation and discovery.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eOrganic synthesis is a key application where DMN is used to form carbon-carbon bonds through reactions like Michael additions and alkylation.\u003c\/li\u003e\n\u003cli\u003ePharmaceutical research benefits from DMN’s ability to participate in the synthesis of complex heterocyclic compounds.\u003c\/li\u003e\n\u003cli\u003eMaterial science applications rely on DMN for creating functional organic materials with specific chemical properties.\u003c\/li\u003e\n\u003cli\u003eAnalytical chemistry uses DMN as a reagent in the preparation of standard solutions for qualitative and quantitative analysis.\u003c\/li\u003e\n\u003cli\u003eIndustrial chemical processes incorporate DMN to produce intermediates for a wide range of chemical products.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 7321-55-3\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Synthetic Reagents \u0026gt; C-X(Non-Halogen) Bond Formation\u003c\/li\u003e\n\u003cli\u003ePack sizes: Available in various quantities as per supplier specifications\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from light and moisture\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eDMN should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to use airtight containers made of materials that are chemically inert, such as glass or polyethylene, to minimize exposure to moisture and air. Due to its reactivity, it is important to handle DMN with care, using appropriate personal protective equipment like gloves and safety goggles. Avoid exposure to high temperatures and direct sunlight to ensure safe storage. In laboratory settings, proper ventilation and adherence to standard safety protocols are essential to prevent any potential hazards. Always ensure that DMN is kept away from incompatible substances to maintain a safe working environment.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086763143386,"sku":"TCI2510D551426430","price":3317000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086763176154,"sku":"TCI2510D551426431","price":11637000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D5514.jpg?v=1769142111"},{"product_id":"tci2510m330841876","title":"TCI M3308 1195-98-8 2-Methyl-2-phenylpropanenitrile","description":"\u003cp\u003e\u003cstrong\u003e2-Methyl-2-phenylpropanenitrile\u003c\/strong\u003e (CAS 1195-98-8) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eGC Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C10H11N\u003c\/li\u003e\n\u003cli\u003eCAS number: 1195-98-8\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(GC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: M3308\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e 2-Methyl-2-phenylpropionitrile; Dimethylphenylacetonitrile\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48087746281690,"sku":"TCI2510M330841876","price":1997000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48087746314458,"sku":"TCI2510M330841877","price":7027000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510M3308.jpg?v=1768205877"},{"product_id":"tci2510b12746490","title":"TCI B1274 7188-38-7 tert-Butyl Isocyanide","description":"\u003cp\u003e\u003cstrong\u003etert-Butyl Isocyanide\u003c\/strong\u003e (CAS 7188-38-7) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eGC Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C5H9N\u003c\/li\u003e\n\u003cli\u003eCAS number: 7188-38-7\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;95.0%(GC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: B1274\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5mL","offer_id":48085586641114,"sku":"TCI2510B12746490","price":4105000.0,"currency_code":"IDR","in_stock":true},{"title":"25mL","offer_id":48085586673882,"sku":"TCI2510B12746491","price":13267000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B1274_13b56828-b597-440c-bdcf-f73ad58f190f.jpg?v=1767232209"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-cyanation-synthetic-reagents.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}