{"title":"{Disable Category} Anesthetics Ingredients (for Research and Experimental Use)[USP drug classification]","description":"\u003cp\u003e{Disable Category} Anesthetics Ingredients (for Research and Experimental Use)[USP drug classification] — reagen TCI untuk riset dan industri. Tersedia di Indonesia melalui AMI Scientific.\u003c\/p\u003e","products":[{"product_id":"tci2510b646713360","title":"TCI B6467 61-12-1 Dibucaine Hydrochloride","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eDibucaine Hydrochloride is the water-soluble salt form of a well-characterised quinoline carboxamide local anaesthetic compound. It is widely recognised in laboratories as the selective inhibitor used in the classical dibucaine number assay for butyrylcholinesterase variants. Researchers also employ it as a reference compound in enzyme inhibition kinetics and membrane interaction studies. Supplied by TCI in 5 g and 25 g sizes, the material is intended for research and experimental use only.\u003c\/p\u003e\n\u003ch3\u003eScientific References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eYamadori et al. (2009). Allergic contact dermatitis from dibucaine hydrochloride, chlorpheniramine maleate, and naphazoline hydrochloride in an over‐the‐counter topical antiseptic. \u003cem\u003eContact Dermatitis\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1111\/j.1600-0536.2009.01556.x\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1111\/j.1600-0536.2009.01556.x\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eLaPlanche (1991). 13C NMR Chemical Shift Assignments in Dibucaine and Dibucaine Hydrochloride Determined by Two-Dimensional NMR Spectroscopy. \u003cem\u003eSpectroscopy Letters\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1080\/00387019108020651\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1080\/00387019108020651\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eYOKOYAMA (1997). Surface Potential of Mixed Micelles Composed of Dibucaine Hydrochloride and Heptaethylene Glycol Dodecyl Ether.. \u003cem\u003eChemical and Pharmaceutical Bulletin\u003c\/em\u003e \u003ca href=\"https:\/\/doi.org\/10.1248\/cpb.45.2104\" target=\"_blank\" rel=\"nofollow noopener\"\u003edoi:10.1248\/cpb.45.2104\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eReferences were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.\u003c\/small\u003e\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48085941518554,"sku":"TCI2510B646713360","price":1010000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48085941551322,"sku":"TCI2510B646713361","price":3484000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6467.jpg?v=1768816058"},{"product_id":"tci2510l015637068","title":"TCI L0156 137-58-6 Lidocaine","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eLidocaine is a local anaesthetic compound of the amide class, structurally an acetamide derivative bearing a diethylaminoacetyl group attached to a 2,6-dimethylaniline ring. In the laboratory context, this material is supplied as a pharmaceutical research reagent intended for experimental purposes only, not for use in humans. Its role is that of a reference compound and test substance in studies of the mechanism of action of sodium channel blockers, in analytical method development, and in formulation research. Its availability as reagent-grade material makes it a consistent benchmark across a wide range of experimental designs.\u003c\/p\u003e\n\u003cp\u003eThe property that makes lidocaine a preferred research material is its relatively high chemical stability compared with ester-class local anaesthetics, because the amide bond is far more resistant to both enzymatic and chemical hydrolysis. As the free base, the compound is a solid that dissolves readily in organic solvents and can be converted into a water-soluble salt form as experimental requirements dictate. Its amphiphilic character, combining an ionisable tertiary amine group with a lipophilic aromatic ring, makes it an attractive model for studying partitioning behaviour between aqueous and lipid environments.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this reagent is typically used in pharmaceutical research settings: university pharmacy and pharmacology departments, analytical chemistry laboratories developing and validating assay methods, and formulation development units working on dosage form research. It serves as a reference standard material in chromatographic work and as a model compound in mechanistic and physicochemical studies. Throughout, the material is handled strictly as an experimental reagent within controlled laboratory conditions.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSodium channel blocker mechanism studies — its well-defined amide structure and reagent-grade consistency make it a dependable test substance for probing how this class of compounds exerts its blocking action.\u003c\/li\u003e\n\u003cli\u003eAnalytical method development and validation — the compound's chemical stability and defined identity allow it to serve as a reliable reference peak when establishing chromatographic or spectroscopic procedures.\u003c\/li\u003e\n\u003cli\u003ePharmaceutical formulation research — its ability to exist as either a free base or a water-soluble salt gives formulators flexibility when investigating dosage form behaviour under different vehicle systems.\u003c\/li\u003e\n\u003cli\u003ePartitioning and physicochemical modelling — the amphiphilic combination of an ionisable tertiary amine and a lipophilic aromatic ring makes it a useful model for lipid–water distribution work.\u003c\/li\u003e\n\u003cli\u003eComparative stability investigations — because the amide bond resists hydrolysis more strongly than ester linkages, it functions well as the stable comparator in degradation and stability study designs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 137-58-6\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Biochemicals and Reagents \u0026gt; Pharmaceutical Research Reagents (for Experimental Use)\u003c\/li\u003e\n\u003cli\u003ePhysical form: solid (free base)\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in the standard TCI catalogue pack sizes; please confirm the required quantity when ordering\u003c\/li\u003e\n\u003cli\u003eStorage note: store under the conditions stated on the manufacturer's label and safety data sheet\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the material in its original tightly closed container, kept in a cool, dry and well-ventilated area away from direct sunlight, moisture and incompatible substances, following the conditions stated on the manufacturer's label and safety data sheet. Glass containers with chemically resistant closures are generally suitable, and containers should be resealed promptly after each use to limit moisture uptake. Handle the solid in a fume hood or a well-ventilated workspace, wearing a laboratory coat, gloves and eye protection, and avoid the generation of dust. Weigh and transfer the material using clean, dry utensils to prevent cross-contamination. As a pharmaceutical research reagent supplied for experimental use only, it must not be administered to humans, and all handling and disposal should follow the institution's laboratory safety procedures and applicable regulations.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48087484793050,"sku":"TCI2510L015637068","price":1187000.0,"currency_code":"IDR","in_stock":true},{"title":"100g","offer_id":48087484825818,"sku":"TCI2510L015637069","price":3282000.0,"currency_code":"IDR","in_stock":true},{"title":"500g","offer_id":48087484858586,"sku":"TCI2510L015637070","price":10675000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510L0156.jpg?v=1767121505"},{"product_id":"tci2510a34674290","title":"TCI A3467 23964-58-1 Articaine","description":"\u003cp\u003e\u003cstrong\u003eArticaine\u003c\/strong\u003e (CAS 23964-58-1) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eHPLC Grade\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C13H20N2O3S\u003c\/li\u003e\n\u003cli\u003eCAS number: 23964-58-1\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(HPLC)(T)\u003c\/li\u003e\n\u003cli\u003eTCI product code: A3467\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e Carticaine; Methyl 4-Methyl-3-(2-(propylamino)propanamido)thiophene-2-carboxylate; Methyl 4-Methyl-3-[(N-propylalanyl)amino]-2-thiophenecarboxylate\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"250mg","offer_id":48085468709082,"sku":"TCI2510A34674290","price":2349000.0,"currency_code":"IDR","in_stock":true},{"title":"1g","offer_id":48085468741850,"sku":"TCI2510A34674291","price":8253000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510A3467.jpg?v=1768358905"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-disable-category-anesthetics-ingredients-for-research-and-experimental-use-usp-drug-classification.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}