{"title":"{Disable Category} Antigout Agents (for Research and Experimental Use)[USP drug classification]","description":"\u003cp\u003e{Disable Category} Antigout Agents (for Research and Experimental Use)[USP drug classification] — reagen TCI untuk riset dan industri. Tersedia di Indonesia melalui AMI Scientific.\u003c\/p\u003e","products":[{"product_id":"tci2510f084730838","title":"TCI F0847 144060-53-7 Febuxostat","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eFebuxostat is a pharmacological compound widely used in pharmacology and biochemical research for studying purine metabolism and regulating uric acid levels in the body. As a research reagent, it plays a crucial role in experimental settings where understanding metabolic pathways and enzyme activity is essential. Its ability to inhibit xanthine oxidase makes it a key component in experiments related to gout and nephrotic syndrome. This compound is particularly valuable for researchers aiming to explore the biochemical mechanisms behind these conditions and develop targeted therapeutic strategies.\u003c\/p\u003e\n\u003cp\u003eThe chemical stability of Febuxostat, along with its versatility as both a substrate and inhibitor in enzymatic reactions, makes it a preferred choice in biochemical research. Its consistent performance under controlled laboratory conditions ensures reliable results, which is vital for scientific accuracy. Additionally, its availability in solid form and compatibility with standard storage conditions simplify its use in various experimental setups. These characteristics make it an essential tool for researchers working on enzyme activity assays and metabolic studies.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, Febuxostat is commonly used in health-related and metabolic disease research. It is frequently found in pharmaceutical, biomedical, and clinical research settings, especially in academic institutions and research organizations focused on metabolic disorders and therapeutic development. Its role in supporting scientific inquiry and innovation in the field of biomedicine is well established.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePharmacological research for studying purine metabolism and uric acid regulation in experimental models.\u003c\/li\u003e\n\u003cli\u003eDevelopment of therapeutic strategies for gout and nephrotic syndrome through enzyme inhibition studies.\u003c\/li\u003e\n\u003cli\u003eEnzyme activity assays to evaluate the effects of compounds on xanthine oxidase activity.\u003c\/li\u003e\n\u003cli\u003eMetabolic pathway analysis in biochemical research to understand purine-related diseases.\u003c\/li\u003e\n\u003cli\u003eClinical research applications in pharmaceutical and biomedical laboratories for drug development and testing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 144060-53-7\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Biochemicals and Reagents \u0026gt; Pharmaceutical Research Reagents\u003c\/li\u003e\n\u003cli\u003ePack sizes: As available\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eFebuxostat should be stored in a cool, dry environment, away from direct sunlight and moisture to maintain its chemical stability. It is recommended to keep it in airtight containers to prevent contamination and degradation. In laboratory settings, it is important to handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. Proper labeling of storage containers is essential for safe handling and easy identification. Regular monitoring of storage conditions ensures the compound remains effective for experimental use. Adherence to standard laboratory safety protocols is crucial when working with this reagent.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48087039705306,"sku":"TCI2510F084730838","price":2626000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48087039738074,"sku":"TCI2510F084730839","price":8430000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510F0847.jpg?v=1769142426"},{"product_id":"tci2510p197547689","title":"TCI P1975 57-66-9 Probenecid","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI P1975 Probenecid (CAS 57-66-9) is a benzoic acid derivative with a sulfonamide group. In medicine it is known as a uricosuric agent. In the laboratory it is used mainly as an inhibitor of organic anion transporters, which makes it useful in many kinds of biological experiments. TCI lists this product under Animal Disease Models Preparation. Researchers often give probenecid together with another compound to extend how long the animal is exposed to that compound, or to strengthen its effect.\u003c\/p\u003e\n\u003cp\u003eProbenecid is useful because it blocks organic anion transporters. This slows the removal of certain compounds from tissues and cells, so researchers can keep a co-administered compound in the body longer without changing the compound itself. A well-known example is the chronic Parkinson's disease model in mice, which combines MPTP with probenecid. In cell biology, probenecid is often added to calcium imaging assays so that cells do not quickly pump out fluorescent dyes such as AM ester calcium indicators. It is also known as an inhibitor of pannexin-1 channels. Because it works in several of these settings, it is a flexible supporting reagent.\u003c\/p\u003e\n\u003cp\u003eIn Indonesia, probenecid is a practical supporting reagent for pharmacology, neuroscience, and cell biology laboratories. University research groups, teaching hospitals, and institutional laboratories can use it to build animal disease models, especially chronic neurodegeneration models, and to improve the reliability of fluorescence-based cell assays. A single compound that serves both in vivo and in vitro work fits well in laboratories that run several research programs with limited reagent budgets.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChronic Parkinson's disease mouse models:\u003c\/strong\u003e Probenecid is combined with MPTP to build the well-known chronic Parkinson's model in mice, because it slows the clearance of the neurotoxic compound.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtending compound exposure in animal studies:\u003c\/strong\u003e By inhibiting organic anion transporters, probenecid slows the removal of certain co-administered compounds from tissues, which prolongs exposure in experimental animals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCalcium imaging assays:\u003c\/strong\u003e Probenecid is added to cell loading buffers so that AM ester calcium indicators stay inside the cells, giving stronger and more stable fluorescent signals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrganic anion transporter studies:\u003c\/strong\u003e As a recognized inhibitor of organic anion transporters, probenecid serves as a reference tool for studying transporter-dependent uptake and efflux in cells and tissues.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePannexin-1 channel research:\u003c\/strong\u003e Probenecid is known to inhibit pannexin-1 channels, so it is used in cell biology and neuroscience experiments that study channel-mediated signaling and release.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI (product code P1975)\u003c\/li\u003e\n\u003cli\u003eCAS number: 57-66-9\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Biochemicals and Reagents \u0026gt; Animal Disease Models Preparation\u003c\/li\u003e\n\u003cli\u003ePack sizes: Please refer to the available options on the product page\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid. Check the label and certificate of analysis for details.\u003c\/li\u003e\n\u003cli\u003eStorage: Follow the storage conditions stated on the manufacturer's label\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore probenecid in its original tightly closed container, in a cool, dry, well-ventilated place away from direct light and moisture, and follow the storage conditions on the TCI label. Keep it away from incompatible substances such as strong oxidizing agents. When weighing or preparing solutions, wear standard protective equipment, including a laboratory coat, safety glasses, and gloves. Avoid creating or breathing in dust, and work in a fume hood or a well-ventilated area. Label prepared stock solutions clearly with the concentration and preparation date. Always read the manufacturer's Safety Data Sheet before use, and dispose of waste according to your institution's rules and local regulations.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48088088674522,"sku":"TCI2510P197547689","price":1541000.0,"currency_code":"IDR","in_stock":true},{"title":"100g","offer_id":48088088707290,"sku":"TCI2510P197547690","price":4468000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510P1975.jpg?v=1767135520"},{"product_id":"tci2510a09071201","title":"TCI A0907 315-30-0 Allopurinol","description":"\u003cp\u003e\u003cstrong\u003eAllopurinol\u003c\/strong\u003e (CAS 315-30-0) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eReagent Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C5H4N4O\u003c\/li\u003e\n\u003cli\u003eCAS number: 315-30-0\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(T)\u003c\/li\u003e\n\u003cli\u003eTCI product code: A0907\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e 4-Hydroxypyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidin-4-ol\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48085324136666,"sku":"TCI2510A09071201","price":1213000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510A0907.jpg?v=1769141357"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-disable-category-antigout-agents-for-research-and-experimental-use-usp-drug-classification.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}