{"title":"Guloses [Glycoscience]","description":"\u003cp\u003e\u003cstrong\u003eGuloses [Glycoscience]\u003c\/strong\u003e — menghimpun gula langka turunan L-gulosa beserta senyawa turunannya, termasuk bentuk lakton dan asetonida terlindungi yang berperan sebagai bahan awal sintesis karbohidrat kompleks dan molekul bioaktif turunan gula langka dalam kimia glikosains.\u003c\/p\u003e\u003cp\u003eGuloses dipakai kimiawan karbohidrat sebagai bahan awal kiral dalam sintesis total gula jarang dan turunan vitamin C, mengingat L-gulonic acid gamma-lactone berperan sebagai perantara jalur biosintesis asam askorbat. Senyawa terlindungi seperti di-O-isopropilidena-keto-L-gulonic acid dipakai dalam sintesis intermediet berbasis gula pada riset kimia organik.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510g023931859\"\u003eTCI G0239 6027-89-0 L-Gulose\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510d219122285\"\u003eTCI D2191 68539-16-2 (-)-2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic Acid Monohydrate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510g023531854\"\u003eTCI G0235 1128-23-0 L-(+)-Gulonic Acid gamma-Lactone\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan konfigurasi stereokimia dan kemurnian optik senyawa karena gulosa memiliki banyak isomer gula terkait, serta bentuk gugus pelindung (isopropilidena) yang harus sesuai dengan tahap sintesis yang direncanakan. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Glycoscience, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-monosaccharides-glycoscience\"\u003eMonosaccharides [Glycoscience]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-monosaccharides-glycoscience\"\u003eMonosaccharides [Glycoscience]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-functional-oligosaccharides\"\u003eFunctional Oligosaccharides\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-functional-oligosaccharides\"\u003eFunctional Oligosaccharides\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-applications-using-glyco-materials\"\u003eApplications Using Glyco-materials\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l3-glyco-building-blocks\"\u003eGlyco Building Blocks\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l2-glycoscience\"\u003eGlycoscience\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510d219122285","title":"TCI D2191 68539-16-2 (-)-2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic Acid Monohydrate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e(-)-2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic Acid Monohydrate is a protected form of 2-keto-L-gulonic acid, a very well known intermediate in the manufacturing route to vitamin C. Two pairs of hydroxyl groups on the parent molecule are tied up as isopropylidene acetals, leaving only the carboxylic acid group free to react. In the laboratory the compound plays a dual role: as a synthetic intermediate toward ascorbic acid and its derivatives, and as an enantiomerically pure chiral compound that can be exploited in carbohydrate chemistry and asymmetric synthesis. Its classification as a glycoscience material reflects how closely it sits to sugar chemistry.\u003c\/p\u003e\n\u003cp\u003eThe main properties that lead researchers to select this compound are the combination of chiral purity and a selective protection pattern. The isopropylidene groups shield the diols from side reactions while simultaneously locking the ring conformation, so that reactions at the carboxylic acid group proceed with controlled stereochemistry and repeatable yields. This protection can also be removed under mildly acidic conditions, giving the researcher full control over the sequence of synthetic steps. Being a carboxylic acid, the compound is able to form diastereomeric salts with racemic amines, which is the basis of its use as a resolving agent.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories this material is typically handled in academic and industrial research settings that work on vitamin C chemistry, carbohydrate derivatives, and stereoselective synthesis. It is used at bench scale for multi-step preparations, for method development where a defined chiral building block is required, and in teaching or research groups that need a reliable protected sugar acid. As a TCI catalogue item it is ordered as a research chemical rather than a production raw material.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAscorbic acid derivative synthesis — the compound is the protected precursor on the established vitamin C route, so only the free carboxylic acid needs to be functionalised before deprotection delivers the target skeleton.\u003c\/li\u003e\n\u003cli\u003eChiral resolution of racemic amines — as a single-enantiomer carboxylic acid it forms diastereomeric salts with racemic bases, allowing separation of the two enantiomers by differential crystallisation.\u003c\/li\u003e\n\u003cli\u003eAsymmetric synthesis building block — the fixed stereocentres and conformationally locked acetal rings transfer defined stereochemistry into new bonds formed at the carboxylate position.\u003c\/li\u003e\n\u003cli\u003eCarbohydrate chemistry research — because it derives from a sugar acid with selectively masked diols, it serves as a convenient starting point for preparing modified glycoscience targets.\u003c\/li\u003e\n\u003cli\u003eProtection and deprotection method development — the isopropylidene acetals are stable during carboxyl-group manipulation yet cleavable under mild acid, making the molecule a useful model substrate for studying protecting-group strategies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCatalogue number: D2191\u003c\/li\u003e\n\u003cli\u003eCAS number: 68539-16-2\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Glycoscience\u003c\/li\u003e\n\u003cli\u003eChemical name: (-)-2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic Acid Monohydrate\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in standard TCI research-scale packaging; please confirm the size required when ordering\u003c\/li\u003e\n\u003cli\u003eStorage: store as indicated on the manufacturer's label and accompanying documentation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eKeep the container tightly closed in a cool, dry, well ventilated area, away from moisture, heat, and direct sunlight, since the acetal protecting groups are sensitive to acidic and humid conditions. Store in the original manufacturer's container or in a clean, chemically compatible glass vessel with a secure closure, clearly labelled and separated from strong acids and oxidising agents. Handle in a fume hood using safety glasses, gloves, and a laboratory coat, weighing the solid carefully to avoid dust formation. Allow refrigerated material to reach room temperature before opening to prevent condensation. Always consult the manufacturer's Safety Data Sheet before use and follow institutional waste disposal procedures.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086503031002,"sku":"TCI2510D219122285","price":929000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D2191.jpg?v=1767104379"},{"product_id":"tci2510g023931859","title":"TCI G0239 6027-89-0 L-Gulose","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI G0239 L-Gulose is a rare hexose sugar that is seldom encountered in meaningful quantities in nature, which is why it is almost always supplied through chemical synthesis or enzymatic conversion rather than isolation from natural sources. As a member of the aldohexose family, L-gulose shares the same molecular formula as glucose but differs in the configuration of its chiral centres. This subtle difference is precisely what makes it so valuable in the glycoscience laboratory: the compound serves as a tool for testing how strictly an enzyme, lectin, or receptor discriminates between the spatial arrangements of hydroxyl groups on sugar molecules that otherwise appear very similar.\u003c\/p\u003e\n\u003cp\u003eThe characteristics that lead researchers to select L-gulose are its rarity and its stereochemical distinctiveness. In plant ascorbic acid biosynthesis, L-gulose is recognised as an intermediate in one of the alternative pathways, making the compound an important material for tracing and providing evidence for that metabolic route. Physically it is a white crystalline solid that dissolves readily in water like other simple sugars, and it can be analysed by chromatography as well as by polarimetry. Its availability in pure form allows the preparation of standard solutions at precisely known concentrations for quantification work.\u003c\/p\u003e\n\u003cp\u003eFor laboratories in Indonesia, a rare sugar of this kind is typically used in academic research groups, university glycobiology and biochemistry laboratories, and institutional research centres working on carbohydrate recognition and plant metabolism. Because it is not obtainable in useful amounts from natural material, reliable access to a synthesised, well-characterised grade is essential for reproducible carbohydrate-specificity studies and for building accurate calibration standards for analytical methods.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eEnzyme specificity screening — L-gulose acts as a stereochemically distinct probe that reveals how strictly a carbohydrate-active enzyme discriminates between hydroxyl configurations on otherwise closely related hexose substrates.\u003c\/li\u003e\n\u003cli\u003eLectin and receptor binding studies — because it shares the molecular formula of glucose but differs in chirality, it tests whether a lectin or receptor recognises spatial arrangement rather than composition alone.\u003c\/li\u003e\n\u003cli\u003eAscorbic acid biosynthesis research — as a known intermediate in an alternative plant pathway, it supports work aimed at tracing and confirming that metabolic route experimentally.\u003c\/li\u003e\n\u003cli\u003eAnalytical standard preparation — its availability in pure form allows precise standard solutions to be prepared for quantification by chromatographic methods in carbohydrate analysis.\u003c\/li\u003e\n\u003cli\u003ePolarimetric and chromatographic method development — the compound is amenable to both polarimetry and chromatography, making it useful when establishing or validating separation and detection methods for rare sugars.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 6027-89-0\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Glycoscience\u003c\/li\u003e\n\u003cli\u003ePack sizes: supplied in the catalogue pack sizes offered for this item; please confirm the currently available option when ordering\u003c\/li\u003e\n\u003cli\u003ePhysical form: white crystalline solid, readily soluble in water\u003c\/li\u003e\n\u003cli\u003eStorage: keep in a tightly closed container in a cool, dry place away from moisture\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the container tightly closed in a cool, dry place, protected from moisture and direct sunlight, since crystalline sugars readily take up atmospheric water and this can affect the accuracy of gravimetric weighing. Use clean, dry glass or chemically compatible plastic containers with well-fitting closures, and reseal immediately after each use. Handle in a well-ventilated area with standard laboratory personal protective equipment, including a laboratory coat, safety glasses, and gloves, and avoid generating dust when weighing the solid. Use dry spatulas to prevent contamination of the stock material, and label any prepared solutions clearly with the concentration and preparation date. Always consult the manufacturer's safety data sheet before first use.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48087099900122,"sku":"TCI2510G023931859","price":2250000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48087099932890,"sku":"TCI2510G023931860","price":6100000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48087099965658,"sku":"TCI2510G023931861","price":24284000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510G0239.jpg?v=1767114876"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-guloses-glycoscience.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}