{"title":"Peptide Nucleic Acid (PNA) Monomers","description":"\u003cp\u003e\u003cstrong\u003ePeptide Nucleic Acid (PNA) Monomers\u003c\/strong\u003e — berisi monomer building block untuk sintesis peptide nucleic acid (PNA), yaitu analog asam nukleat dengan rangka tulang punggung pseudopeptida yang membawa nukleobasa terlindungi gugus Fmoc dan Bhoc. Golongan ini berperan sebagai bahan baku sintesis PNA fase padat.\u003c\/p\u003e\u003cp\u003eMonomer Fmoc-PNA dengan basa adenin, guanin, sitosin, dan timin digunakan pada sintesis fase padat oligomer PNA yang berikatan dengan DNA atau RNA target melalui pasangan basa Watson-Crick namun dengan afinitas dan stabilitas yang berbeda dari asam nukleat alami. Peneliti kimia asam nukleat dan pengembang probe molekular memanfaatkan golongan ini untuk membuat oligomer antisense sintetik dan probe hibridisasi pada penelitian biologi molekular.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510d593426924\"\u003eTCI D5934 169396-92-3 Fmoc-PNA-T-OH\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510d593126921\"\u003eTCI D5931 186046-82-2 Fmoc-PNA-A(Bhoc)-OH\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510d593326923\"\u003eTCI D5933 186046-83-3 Fmoc-PNA-G(Bhoc)-OH\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510d593226922\"\u003eTCI D5932 186046-81-1 Fmoc-PNA-C(Bhoc)-OH\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePilih gugus pelindung basa yang sesuai (Bhoc untuk basa eksosiklik amino, tanpa pelindung tambahan untuk timin) serta strategi Fmoc yang kompatibel dengan protokol sintesis fase padat yang digunakan. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Nucleic Acid Chemistry, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-phosphorylating-agents-and-phosphorothioating-agents-nucleic-acid-synthesis\"\u003ePhosphorylating Agents and Phosphorothioating Agents [Nucleic Acid Synthesis]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-coupling-activators-and-condensing-agents-nucleic-acid-synthesis\"\u003eCoupling Activators and Condensing Agents [Nucleic Acid Synthesis]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-protecting-agents-for-hydroxy-and-amino-groups-nucleic-acid-synthesis\"\u003eProtecting Agents for Hydroxy and Amino Groups [Nucleic Acid Synthesis]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-nucleoside-phosphoramidites-nucleic-acid-synthesis\"\u003eNucleoside Phosphoramidites [Nucleic Acid Synthesis]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-sulfur-transfer-reagents-nucleic-acid-synthesis\"\u003eSulfur Transfer Reagents [Nucleic Acid Synthesis]\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-nucleic-acid-chemistry\"\u003eNucleic Acid Chemistry\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510d593126921","title":"TCI D5931 186046-82-2 Fmoc-PNA-A(Bhoc)-OH","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI D5931 Fmoc-PNA-A(Bhoc)-OH is a peptide nucleic acid (PNA) monomer carrying the adenine base, used as a building block in the solid-phase synthesis of PNA oligomers. The molecule combines a peptide-like aminoethylglycine backbone with a nucleobase, so that genetic information sequences can be assembled using the peptide chemistry techniques already routine in the laboratory. Its terminal amino group is protected with Fmoc (fluorenylmethyloxycarbonyl), while the exocyclic amine on the adenine ring is protected with Bhoc (benzhydryloxycarbonyl). This combination of protecting groups makes the monomer compatible with Fmoc-based synthesis strategies that avoid strong acid at every chain-elongation cycle.\u003c\/p\u003e\n\u003cp\u003eThe characteristic that makes this monomer a preferred choice is its full compatibility with the Fmoc\/Bhoc protocol: terminal deprotection using a weak base, and final cleavage from the resin using a comparatively mild acid. This dual protection pattern suppresses side reactions on the adenine ring during repeated coupling steps, so the PNA chain can be extended with cleaner results and easier purification. The electrostatically neutral PNA backbone also gives the resulting oligomers a distinct binding behaviour compared with conventional nucleic acids, which is why researchers select PNA chemistry in the first place.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this monomer is typically used in university and institutional research groups working on molecular biology, nucleic acid chemistry, and molecular probe development. It is normally ordered together with the other PNA monomers of the set, coupling reagents, and solid-phase resins so that a complete synthesis cycle can be run. Because it is consumed in small quantities per coupling step, it is generally purchased as part of a planned synthesis campaign rather than kept as a bulk stock item.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSolid-phase PNA oligomer synthesis: supplies the adenine position of the target sequence and couples under standard Fmoc peptide chemistry conditions already established in most synthesis laboratories.\u003c\/li\u003e\n\u003cli\u003eMolecular probe and hybridisation probe preparation: the neutral aminoethylglycine backbone gives assembled PNA probes binding characteristics that differ from conventional oligonucleotide probes made by phosphoramidite chemistry.\u003c\/li\u003e\n\u003cli\u003eNucleic acid recognition studies: allows researchers to build defined adenine-containing PNA sequences for investigating sequence-specific interaction with complementary nucleic acid strands.\u003c\/li\u003e\n\u003cli\u003eAntisense and gene-targeting research: provides the adenine building block needed when PNA oligomers are designed to recognise specific genetic sequences under study in a research setting.\u003c\/li\u003e\n\u003cli\u003eMethod development for Fmoc\/Bhoc synthesis protocols: the mild deprotection and cleavage requirements make it suitable for optimising coupling cycles, resin choice, and purification workflows without strong-acid steps.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI (Tokyo Chemical Industry)\u003c\/li\u003e\n\u003cli\u003eCAS Number: 186046-82-2\u003c\/li\u003e\n\u003cli\u003eCatalogue Number: D5931\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Peptide Chemistry\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in research-scale packs; please confirm the currently offered size when ordering\u003c\/li\u003e\n\u003cli\u003eStorage: store in a cool place under the conditions stated on the manufacturer's label and Safety Data Sheet\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the monomer in its original tightly closed container in a cool, dry place, protected from moisture and direct light, following the storage conditions stated on the manufacturer's label and Safety Data Sheet. Fmoc- and Bhoc-protected building blocks are best kept dry, since absorbed moisture can interfere with coupling efficiency; allow the container to reach room temperature before opening to prevent condensation on the solid. Weigh and transfer using clean, dry spatulas and glassware, and dissolve in anhydrous solvent immediately before use. Handle in a fume hood with gloves, safety glasses, and a laboratory coat, avoid inhalation of dust, and dispose of residues and contaminated solvent through the laboratory's chemical waste route. Consult the manufacturer's Safety Data Sheet before first use.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086784114906,"sku":"TCI2510D593126921","price":10709000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D5931.jpg?v=1768205148"},{"product_id":"tci2510d593226922","title":"TCI D5932 186046-81-1 Fmoc-PNA-C(Bhoc)-OH","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI D5932 186046-81-1 Fmoc-PNA-C(Bhoc)-OH is a specialized chemical compound used in chemical biology, particularly in peptide chemistry. This compound plays a crucial role in the synthesis of peptides, serving as a key building block for creating complex molecular structures. Its application extends to various research fields, including biomedical and pharmacological studies, where precise chemical synthesis is essential. In the laboratory, it is widely used for the development of peptides with specific biological functions, such as enzyme inhibitors or receptor modulators.\u003c\/p\u003e\n\u003cp\u003eThe compound's unique chemical properties make it a preferred choice for peptide synthesis. Its complex structure allows for stable and specific peptide bonds, ensuring the accuracy of the final product. The compound is chemically reactive, enabling it to interact with various reagents commonly used in peptide synthesis, such as amino acids and coupling agents. These characteristics make it an essential tool for researchers requiring high precision and reproducibility in their experiments.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, TCI D5932 186046-81-1 Fmoc-PNA-C(Bhoc)-OH is frequently utilized in scientific research related to biomedical, pharmacological, and biotechnological applications. Researchers in educational institutions and research organizations rely on this compound for drug development, understanding biological mechanisms, and testing the biological activity of chemical substances. Its versatility and reliability make it a standard component in many laboratory workflows.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBiomedical Research – This compound is ideal for studying enzyme inhibition and receptor modulation, supporting the development of therapeutic agents.\u003c\/li\u003e\n\u003cli\u003ePeptide Synthesis – Its stable and specific peptide bonding properties make it suitable for creating custom peptides with defined functions.\u003c\/li\u003e\n\u003cli\u003ePharmacological Studies – It is used to develop and test compounds that interact with biological targets, aiding in drug discovery processes.\u003c\/li\u003e\n\u003cli\u003eBiotecnological Applications – Its chemical reactivity supports the creation of bioactive molecules for use in biotechnology and diagnostics.\u003c\/li\u003e\n\u003cli\u003eDrug Development – Researchers use it to synthesize and evaluate potential therapeutic agents for various medical conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand – TCI\u003c\/li\u003e\n\u003cli\u003eCAS Number – 186046-81-1\u003c\/li\u003e\n\u003cli\u003eCategory – Chemistry \u0026gt; Chemical Biology \u0026gt; Peptide Chemistry\u003c\/li\u003e\n\u003cli\u003ePack Sizes – Not specified in the reference\u003c\/li\u003e\n\u003cli\u003ePhysical Form – Not specified in the reference\u003c\/li\u003e\n\u003cli\u003eStorage Note – Store in a cool, dry place away from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eThis compound should be stored in a cool, dry environment, away from direct light, to maintain its chemical integrity. It is recommended to use airtight containers to prevent moisture absorption, which could affect its reactivity and stability. In a laboratory setting, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safe handling. Due to its chemical nature, it should be stored separately from incompatible substances to avoid any potential reactions. Proper labeling of storage containers is essential for safe access and use. Regular monitoring of storage conditions is advised to ensure optimal preservation of the compound’s properties.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086784147674,"sku":"TCI2510D593226922","price":10709000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D5932.jpg?v=1769142147"},{"product_id":"tci2510d593326923","title":"TCI D5933 186046-83-3 Fmoc-PNA-G(Bhoc)-OH","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI D5933 186046-83-3 Fmoc-PNA-G(Bhoc)-OH is a specialized chemical compound used in the field of chemical biology, particularly in peptide chemistry. This compound plays a crucial role in the synthesis of peptides with specific biological activities, making it an essential component in advanced laboratory research. Its unique structure enables precise chemical reactions, supporting the development of bioactive molecules in various scientific applications. In the laboratory, it is widely utilized as a building block for creating complex peptide sequences that are vital for drug discovery and therapeutic research.\u003c\/p\u003e\n\u003cp\u003eThe compound is valued for its stability and controlled reactivity, which are critical for achieving consistent results in peptide synthesis. Its solubility in organic solvents simplifies the mixing and reaction processes, enhancing the efficiency of laboratory workflows. These properties make it a preferred choice for researchers who require high accuracy and reliability in their experiments. The compound’s chemical structure is designed to facilitate selective coupling reactions, ensuring the integrity of the final peptide products.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, TCI D5933 186046-83-3 Fmoc-PNA-G(Bhoc)-OH is commonly used in biomedical and pharmacological research. It supports the development of new drugs, diagnostic tools, and biochemical studies. Due to its high quality and consistent performance, it is a trusted material for researchers working on complex and high-precision experiments. Its application is widespread across various scientific disciplines, contributing to the advancement of life sciences in Indonesia.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePeptide Synthesis: This compound is ideal for solid-phase peptide synthesis due to its functional groups that allow for efficient coupling reactions.\u003c\/li\u003e\n\u003cli\u003eDrug Discovery: It supports the development of bioactive peptides used in pharmaceutical research, enabling the creation of novel therapeutic agents.\u003c\/li\u003e\n\u003cli\u003eDiagnostic Development: Its use in synthesizing peptides for diagnostic purposes helps in creating tools for disease detection and monitoring.\u003c\/li\u003e\n\u003cli\u003eBiomedical Research: The compound is valuable in studies related to protein interactions and cellular signaling pathways.\u003c\/li\u003e\n\u003cli\u003eBiochemical Studies: It is used to investigate the structural and functional properties of peptides in various biological systems.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS Number: 186046-83-3\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Peptide Chemistry\u003c\/li\u003e\n\u003cli\u003ePack Sizes: Available in various quantities as per standard laboratory supply\u003c\/li\u003e\n\u003cli\u003ePhysical Form: Solid powder\u003c\/li\u003e\n\u003cli\u003eStorage Note: Store in a cool, dry place away from light and moisture\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eThis compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to air and contaminants. Due to its reactivity, it should be handled in a well-ventilated laboratory setting, with appropriate personal protective equipment such as gloves and goggles. Avoid contact with incompatible substances, and ensure proper disposal procedures are followed to comply with safety regulations. Regular monitoring of storage conditions is advised to ensure the compound remains stable and effective for laboratory use.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086784213210,"sku":"TCI2510D593326923","price":10709000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D5933.jpg?v=1769142148"},{"product_id":"tci2510d593426924","title":"TCI D5934 169396-92-3 Fmoc-PNA-T-OH","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI D5934 169396-92-3 Fmoc-PNA-T-OH is a chemical compound widely used in the field of chemical biology, particularly in peptide chemistry. It plays a crucial role in the synthesis of peptides, serving as a key building block in the creation of complex molecular structures. This compound is essential for researchers aiming to develop new therapeutic agents, analyze biological systems, or explore molecular interactions. Its application spans various scientific disciplines, making it an indispensable tool in modern laboratory settings.\u003c\/p\u003e\n\u003cp\u003eThe compound is valued for its chemical stability and high reactivity, which are critical for precise chemical reactions. Its ability to form specific bonds with peptide chains ensures accuracy and consistency in synthetic processes. Additionally, Fmoc-PNA-T-OH is compatible with a variety of resin types, making it versatile for different peptide synthesis techniques. These properties make it a preferred choice for scientists requiring reliable and reproducible results in their experiments.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, Fmoc-PNA-T-OH is commonly used in research related to peptide development, protein structure studies, and bioactivity testing. Its reliability and effectiveness have made it a sought-after material among researchers working on drug discovery, molecular biology, and biotechnology projects. Its presence in these laboratories underscores its importance in advancing scientific knowledge and innovation.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePeptide Synthesis: Fmoc-PNA-T-OH is ideal for solid-phase peptide synthesis due to its compatibility with various resins and its ability to form specific peptide bonds.\u003c\/li\u003e\n\u003cli\u003eDrug Discovery: This compound supports the development of new therapeutic agents by enabling the synthesis of bioactive peptides with targeted functionalities.\u003c\/li\u003e\n\u003cli\u003eProtein Structure Analysis: It is used in studies that require the creation of peptide sequences for understanding protein folding and interaction mechanisms.\u003c\/li\u003e\n\u003cli\u003eBioactivity Testing: Researchers utilize Fmoc-PNA-T-OH to synthesize peptides for evaluating their biological activity and potential therapeutic applications.\u003c\/li\u003e\n\u003cli\u003eMolecular Biology Research: Its role in constructing complex peptide structures makes it valuable for studying molecular interactions and cellular processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 169396-92-3\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Peptide Chemistry\u003c\/li\u003e\n\u003cli\u003ePack sizes: Not specified in the provided data\u003c\/li\u003e\n\u003cli\u003ePhysical form: Not specified in the provided data\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from light and moisture\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eFmoc-PNA-T-OH should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its reactivity, it should be handled with care in a well-ventilated laboratory setting. Always wear appropriate personal protective equipment, such as gloves and safety goggles, when working with this compound. Proper storage and handling ensure the compound remains effective and safe for use in chemical synthesis processes.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086784278746,"sku":"TCI2510D593426924","price":10709000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D5934.jpg?v=1768205149"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-peptide-nucleic-acid-pna-monomers.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}