{"title":"Phosphine Ligands (for Cross-Coupling) [Catalysis]","description":"\u003cp\u003e\u003cstrong\u003ePhosphine Ligands (for Cross-Coupling) [Catalysis]\u003c\/strong\u003e — mencakup ligan fosfin mono- dan bidentat dengan berbagai substituen alkil atau aril, termasuk garam fosfonium terkait, yang berperan sebagai ligan pendukung logam transisi dalam katalisis reaksi kopling silang.\u003c\/p\u003e\u003cp\u003eDipakai kimiawan sintesis organik dan katalisis untuk reaksi kopling silang berkatalis paladium atau nikel seperti Suzuki, Negishi, dan Buchwald-Hartwig, tempat sifat elektronik dan sterik ligan fosfin menentukan aktivitas serta selektivitas katalis. Juga digunakan dalam pengembangan katalis baru di laboratorium riset akademik maupun industri kimia halus.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510v013256551\"\u003eTCI V0132 384842-25-5 vBRIDP(regR)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b687213774\"\u003eTCI B6872 5112-95-8 1,2-Bis(diphenylphosphaneyl)ethyne\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t433056085\"\u003eTCI T4330 49676-42-8 Tris(2,4-dimethylphenyl)phosphine\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b693013814\"\u003eTCI B6930 1055888-89-5 3-(Di-tert-butylphosphaneyl)propane-1-sulfonic Acid\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t258553957\"\u003eTCI T2585 58656-04-5 Tricyclohexylphosphonium Tetrafluoroborate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c142915975\"\u003eTCI C1429 6372-42-5 Cyclohexyldiphenylphosphine\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t258453955\"\u003eTCI T2584 131274-22-1 Tri-tert-butylphosphonium Tetrafluoroborate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c298117891\"\u003eTCI C2981 384842-24-4 Cy-vBRIDP(regR)\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePertimbangkan kebasaan dan besar sudut kerucut (cone angle) ligan, serta bentuk penyimpanan sebagai fosfin bebas versus garam fosfonium yang lebih stabil terhadap oksidasi udara. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Cross-Coupling [Catalysis], sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-buchwald-ligands-and-complexes-catalysis\"\u003eBuchwald Ligands and Complexes [Catalysis]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-buchwald-ligands-catalysis\"\u003eBuchwald Ligands [Catalysis]\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-cross-coupling-catalysis\"\u003eCross-Coupling [Catalysis]\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510d383424226","title":"TCI D3834 628333-86-8 1-[2-(Di-tert-butylphosphino)phenyl]-3,5-diphenyl-1H-pyrazole","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e1-[2-(Di-tert-butylphosphino)phenyl]-3,5-diphenyl-1H-pyrazole from TCI, listed under CAS number 628333-86-8, is a phosphine ligand built on a pyrazole framework and designed for the catalysis of cross-coupling reactions. The molecule combines an electron-rich phosphorus atom bearing di-tert-butyl groups with a diphenyl-substituted pyrazole ring, the two connected through a phenylene bridge. In the laboratory, this compound acts as a supporting ligand for transition metals, particularly palladium, where its task is to form the active catalytic complex and to direct the course of the catalytic cycle in reactions that build carbon–carbon and carbon–heteroatom bonds.\u003c\/p\u003e\n\u003cp\u003eThe properties that make this ligand a preferred choice are the combination of high basicity and substantial steric bulk contributed by the di-tert-butylphosphino group. High basicity accelerates the oxidative addition step on less reactive substrates, while the steric bulk promotes the reductive elimination step so that the catalytic cycle turns over more rapidly. The pyrazole ring supplies an additional donor nitrogen atom together with a rigid aromatic framework, giving a directed coordination environment around the metal centre. A structure of this kind generally allows low catalyst loadings and a broad substrate scope.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, a ligand of this type is typically used in synthetic and methodology work where a palladium-catalysed coupling has to be assembled from the metal precursor and the ligand in situ, or pre-formed as a defined complex before use. It suits organic synthesis groups in universities and research institutes, as well as process and formulation development laboratories that prepare intermediates on a small scale and need a coupling system that performs reliably on demanding substrates.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSuzuki–Miyaura coupling: the high basicity of the di-tert-butylphosphino group assists oxidative addition on less reactive aryl substrates, while the steric bulk speeds reductive elimination and turnover.\u003c\/li\u003e\n\u003cli\u003eBuchwald–Hartwig type carbon–nitrogen bond formation: the electron-rich phosphorus centre and rigid pyrazole framework give the directed coordination environment needed for reliable amination of aryl partners.\u003c\/li\u003e\n\u003cli\u003eGeneral carbon–carbon bond construction: the ligand forms active catalytic complexes with palladium and steers the catalytic cycle, supporting couplings that would otherwise stall on hindered substrates.\u003c\/li\u003e\n\u003cli\u003eCarbon–heteroatom coupling methodology studies: the additional donor nitrogen atom of the pyrazole ring offers a defined coordination geometry that researchers can exploit when screening reaction conditions.\u003c\/li\u003e\n\u003cli\u003eLow-loading catalysis work: because the structure generally permits reduced catalyst charges and broad substrate scope, it suits laboratories optimising ligand-to-metal ratios and catalyst economy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 628333-86-8\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Catalysis and Inorganic Chemistry \u0026gt; Cross-Coupling [Catalysis]\u003c\/li\u003e\n\u003cli\u003eChemical name: 1-[2-(Di-tert-butylphosphino)phenyl]-3,5-diphenyl-1H-pyrazole\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in the standard research-scale pack sizes offered by the manufacturer; please confirm the packaging option required when ordering.\u003c\/li\u003e\n\u003cli\u003eStorage: keep in the closed original container under the conditions stated on the manufacturer's label and safety data sheet.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the product in its original tightly closed container, kept in a cool, dry and well-ventilated place away from heat, ignition sources and incompatible materials, and follow the specific storage conditions printed on the manufacturer's label and safety data sheet. As with other trialkylphosphine ligands, minimise exposure to air and moisture during handling; use tightly sealed glass or the supplied original containers rather than transferring to open vessels. Weigh and dispense in a fume hood using an inert atmosphere where the protocol calls for it, and wear a laboratory coat, safety glasses and suitable chemical-resistant gloves. Keep the container closed when not in use, label all secondary containers clearly, and dispose of residues and contaminated consumables through the laboratory's chemical waste procedure. Consult the manufacturer's safety data sheet before first use.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086640558298,"sku":"TCI2510D383424226","price":1546000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48086640591066,"sku":"TCI2510D383424227","price":4470000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D3834.jpg?v=1767106644"},{"product_id":"tci2510b27098335","title":"TCI B2709 161265-03-8 4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene","description":"\u003cp\u003e\u003cstrong\u003e4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene\u003c\/strong\u003e (CAS 161265-03-8) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eGC Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C39H32OP2\u003c\/li\u003e\n\u003cli\u003eCAS number: 161265-03-8\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(GC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: B2709\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e Xantphos\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48085673771226,"sku":"TCI2510B27098335","price":1378000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48085673803994,"sku":"TCI2510B27098336","price":4751000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48085673836762,"sku":"TCI2510B27098337","price":16133000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B2709_a01ae08d-27fb-441f-84af-46c6c6b59945.jpg?v=1767338005"},{"product_id":"tci2510b523911837","title":"TCI B5239 940934-47-4 4,5-Bis(dicyclohexylphosphino)-9,9-dimethylxanthene","description":"\u003cp\u003e\u003cstrong\u003e4,5-Bis(dicyclohexylphosphino)-9,9-dimethylxanthene\u003c\/strong\u003e (CAS 940934-47-4) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eGC Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C39H56OP2\u003c\/li\u003e\n\u003cli\u003eCAS number: 940934-47-4\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;97.0%(GC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: B5239\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"200mg","offer_id":48085860188378,"sku":"TCI2510B523911837","price":1462000.0,"currency_code":"IDR","in_stock":true},{"title":"1g","offer_id":48085860221146,"sku":"TCI2510B523911838","price":4807000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B5239_8968e7d3-81bf-4e16-9ce5-1780519639a0.jpg?v=1767856027"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-phosphine-ligands-for-cross-coupling-catalysis.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}