{"title":"Phosphonium Salts, Uronium Salts, Formamidinium Salts [Coupling Reagents]","description":"\u003cp\u003e\u003cstrong\u003ePhosphonium Salts, Uronium Salts, Formamidinium Salts [Coupling Reagents]\u003c\/strong\u003e — berisi garam fosfonium, uronium, dan formamidinium yang berfungsi sebagai aktivator gugus karboksilat dalam pembentukan ikatan amida. Anion pendampingnya bervariasi, mulai dari tetrafluoroborat hingga heksafluorofosfat, yang memengaruhi kelarutan dan reaktivitas reagen.\u003c\/p\u003e\u003cp\u003ePhosphonium Salts, Uronium Salts, Formamidinium Salts [Coupling Reagents] merupakan reagen kopling yang banyak dipakai dalam sintesis peptida fase padat maupun larutan untuk membentuk ikatan amida secara efisien dan cepat. Peneliti kimia organik dan farmasi menggunakannya pada sintesis oligopeptida, konjugasi bioaktif, serta pembuatan senyawa amida lain yang memerlukan kondisi reaksi ringan dengan epimerisasi minimal.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510t356955219\"\u003eTCI T3569 255825-38-8 N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Tetrafluoroborate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c137915903\"\u003eTCI C1379 135540-11-3 1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium Hexafluorophosphate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t292954409\"\u003eTCI T2929 265651-18-1 N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium Hexafluorophosphate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c140815947\"\u003eTCI C1408 37091-73-9 2-Chloro-1,3-dimethylimidazolinium Chloride\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t282154290\"\u003eTCI T2821 212333-72-7 N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c163916288\"\u003eTCI C1639 37091-73-9 2-Chloro-1,3-dimethylimidazolinium Chloride (ca. 25% in Dichloromethane)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510t222453511\"\u003eTCI T2224 105832-38-0 N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium Tetrafluoroborate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c165116306\"\u003eTCI C1651 101385-69-7 2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan jenis anion (tetrafluoroborat atau heksafluorofosfat), kemurnian, serta kestabilan penyimpanan, karena sebagian reagen kopling bersifat higroskopis dan sensitif terhadap kelembapan sehingga perlu disimpan dalam wadah kedap udara. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Coupling [Synthetic Reagents], sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-peptide-coupling-agents\"\u003ePeptide Coupling Agents\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-active-esters-additives-coupling-reagents\"\u003eActive Esters, Additives [Coupling Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-coupling-reagents-other\"\u003eCoupling Reagents (Other)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-triflate-formation-coupling-reagents\"\u003eTriflate Formation [Coupling Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-carbodiimides-coupling-reagents\"\u003eCarbodiimides [Coupling Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-phosgene-derivatives-coupling-reagents\"\u003ePhosgene Derivatives [Coupling Reagents]\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-coupling-synthetic-reagents\"\u003eCoupling [Synthetic Reagents]\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510c140815947","title":"TCI C1408 37091-73-9 2-Chloro-1,3-dimethylimidazolinium Chloride","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C1408 2-Chloro-1,3-dimethylimidazolinium chloride (DMC, CAS 37091-73-9) is a versatile imidazolinium-based activating agent for peptide and organic synthesis. It converts carboxylic acids into activated species for amide bond formation and serves as an efficient dehydrating agent. DMC is also valued for activating hydroxyl groups, including in carbohydrate chemistry under aqueous conditions. Because the reagent is strongly moisture sensitive, handle it under inert gas and keep containers tightly sealed.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086068265178,"sku":"TCI2510C140815947","price":1490000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086068297946,"sku":"TCI2510C140815948","price":4751000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1408.jpg?v=1767096891"},{"product_id":"tci2510c163916288","title":"TCI C1639 37091-73-9 2-Chloro-1,3-dimethylimidazolinium Chloride (ca. 25% in Dichloromethane)","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e2-Chloro-1,3-dimethylimidazolinium Chloride (ca. 25% in Dichloromethane) is a chemical compound widely used in laboratory settings, particularly in organic chemistry and peptide synthesis. This compound is known for its reactivity and is commonly employed in substitution reactions and molecular modification processes. Its solubility in dichloromethane makes it suitable for various chemical experiments. In Indonesian laboratories, it is frequently used for research in chemical biology and organic synthesis. The compound is preferred due to its stability and effectiveness in controlled environments, making it a reliable choice for scientific studies and academic research.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48086082289882,"sku":"TCI2510C163916288","price":2025000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1639.jpg?v=1767097255"},{"product_id":"tci2510c165116306","title":"TCI C1651 101385-69-7 2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate is a chemical compound widely used in peptide chemistry and organic synthesis. Its unique structure allows it to participate in various chemical reactions, making it a valuable reagent in laboratory settings. This compound is particularly useful in biological and pharmaceutical research due to its reactivity and stability under controlled conditions. It is commonly applied in the synthesis of peptides, modification of organic molecules, and catalytic processes. Its availability in different packaging options makes it accessible for researchers in Indonesia, supporting scientific advancements in chemistry and biotechnology.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086082846938,"sku":"TCI2510C165116306","price":2362000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086082879706,"sku":"TCI2510C165116307","price":7730000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C1651.jpg?v=1768204615"},{"product_id":"tci2510c273317589","title":"TCI C2733 1075198-30-9 (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eThis complex chemical compound, TCI C2733 (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate, is a specialized reagent used in chemical biology and peptide chemistry. It serves as a key component in the synthesis of organic compounds and bioactive molecules, playing a crucial role in laboratory research that demands high reactivity and molecular specificity. Its unique structure enables it to participate in reactions that produce highly structured products, making it indispensable in advanced chemical processes.\u003c\/p\u003e\n\u003cp\u003eThe compound's complex molecular architecture and high reactivity make it a preferred choice for researchers seeking precision in synthetic reactions. It is known for its stability under controlled conditions, although it is sensitive to moisture and air exposure. These properties make it ideal for applications where exact control over reaction conditions is essential. Its ability to facilitate the formation of specific molecular structures enhances its utility in both academic and industrial research settings.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this compound is widely used by researchers in chemical biology, pharmaceutical development, and materials science. Its application spans various experimental protocols, including the synthesis of complex organic molecules and the development of bioactive compounds. Due to its unique properties, it is a valuable tool for scientists aiming to achieve precise and reproducible results in their work.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePeptide Synthesis: This compound is ideal for peptide chemistry due to its ability to facilitate the formation of specific molecular structures, enhancing the efficiency of synthetic processes.\u003c\/li\u003e\n\u003cli\u003eBioactive Compound Development: Its high reactivity and molecular specificity make it a preferred reagent in the creation of bioactive molecules for pharmaceutical research.\u003c\/li\u003e\n\u003cli\u003eOrganic Chemistry Research: The compound's complex structure supports its use in the synthesis of complex organic compounds, enabling precise chemical transformations.\u003c\/li\u003e\n\u003cli\u003eMolecular Specificity Studies: Its unique reactivity allows researchers to study molecular interactions with high accuracy, supporting advanced chemical investigations.\u003c\/li\u003e\n\u003cli\u003eAdvanced Synthetic Pathways: It is used in multi-step synthetic routes where controlled reactivity and structural precision are critical for successful outcomes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 1075198-30-9\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Peptide Chemistry\u003c\/li\u003e\n\u003cli\u003ePack sizes: Not specified\u003c\/li\u003e\n\u003cli\u003ePhysical form: Not specified\u003c\/li\u003e\n\u003cli\u003eStorage note: Requires protection from moisture and air exposure\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eThis compound should be stored in a dry, cool environment away from moisture and air exposure to maintain its stability and reactivity. It is recommended to use airtight containers made of inert materials such as glass or high-density polyethylene to prevent contamination and degradation. Due to its sensitivity, it should be handled in a controlled laboratory setting with appropriate safety measures in place. Researchers should avoid prolonged exposure to air and moisture to ensure the compound remains effective for its intended applications. Proper storage conditions are essential to preserve its chemical integrity and ensure consistent performance in experimental protocols.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086194323674,"sku":"TCI2510C273317589","price":1659000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086194356442,"sku":"TCI2510C273317590","price":5763000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C2733.jpg?v=1769144359"},{"product_id":"tci2510e091628744","title":"TCI E0916 136849-72-4 O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium Tetrafluoroborate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium Tetrafluoroborate is a specialized chemical compound commonly referred to as TCI E0916. This compound is widely used in laboratory settings for its unique reactivity and specificity in peptide chemistry. It plays a crucial role in the synthesis of complex peptides, particularly in peptide coupling reactions. Due to its chemical structure, it is highly effective in forming amide bonds under controlled conditions, making it an essential tool for researchers in chemical biology.\u003c\/p\u003e\n\u003cp\u003eThis compound is known for its high reactivity and stability under specific conditions, which makes it a preferred choice for various synthetic applications. Its ability to function as an efficient coupling agent is due to its molecular structure, which allows it to react selectively with organic substrates. The compound’s stability in anhydrous environments and at low temperatures further enhances its utility in laboratory processes. These properties ensure reliable results in peptide synthesis and related chemical reactions.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this compound is commonly used in biochemical research and peptide synthesis projects. It is particularly favored by academic institutions and research centers that focus on chemical biology and medicinal chemistry. Its application in these settings supports the development of new pharmaceutical compounds and bioactive molecules. The compound’s versatility and effectiveness make it a valuable resource for scientists working in these fields.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePeptide Synthesis: This compound is ideal for synthesizing complex peptides due to its high reactivity and specificity in forming amide bonds.\u003c\/li\u003e\n\u003cli\u003eBiochemical Research: It supports research in chemical biology by enabling the creation of custom peptide sequences for various studies.\u003c\/li\u003e\n\u003cli\u003eOrganic Chemistry Reactions: Its ability to react with a wide range of organic substrates makes it suitable for amide coupling reactions.\u003c\/li\u003e\n\u003cli\u003eAnhydrous Reaction Conditions: The compound remains stable in anhydrous environments, making it suitable for reactions requiring dry conditions.\u003c\/li\u003e\n\u003cli\u003eLow-Temperature Reactions: It functions effectively at low temperatures, making it a preferred choice for controlled synthesis processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 136849-72-4\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Peptide Chemistry\u003c\/li\u003e\n\u003cli\u003ePack sizes: Available in various quantities as per supplier specifications\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid powder\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from moisture and light\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eThis compound should be stored in a cool, dry environment, away from moisture and direct light to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its reactivity, it should be handled in a well-ventilated area, and appropriate personal protective equipment should be worn. The compound is stable under anhydrous conditions and at low temperatures, making it suitable for storage in a refrigerator if required. It is important to avoid contact with water or other reactive substances to ensure its effectiveness and safety in laboratory use.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086907814106,"sku":"TCI2510E091628744","price":676000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48086907846874,"sku":"TCI2510E091628745","price":2222000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510E0916.jpg?v=1768205247"},{"product_id":"tci2510e130629271","title":"TCI E1306 333717-40-1 O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium Hexafluorophosphate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI E1306, also known as O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium Hexafluorophosphate, is a synthetic reagent widely used in chemical synthesis, particularly in coupling reactions. This compound plays a crucial role in facilitating the formation of chemical bonds between molecules, making it an essential tool in organic chemistry research. Its unique molecular structure allows for highly specific and efficient reactions, which are vital in the development of new compounds and materials.\u003c\/p\u003e\n\u003cp\u003eOne of the key properties that make TCI E1306 a preferred choice is its high reactivity and ability to form stable bonds with various substrates. The compound’s controlled reactivity and molecular stability ensure consistent results in chemical processes, making it reliable for laboratory applications. Its effectiveness as a coupling reagent is further enhanced by its ability to maintain reaction specificity, which is critical in complex synthetic pathways.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, TCI E1306 is commonly used in scientific research and chemical product development. It is particularly relevant for researchers in organic chemistry, pharmacy, and biochemistry due to its versatility and efficiency. Its availability and performance make it a valuable resource for both academic and industrial applications in the region.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eOrganic synthesis research: TCI E1306 is ideal for creating complex organic molecules due to its high reactivity and specificity in coupling reactions.\u003c\/li\u003e\n\u003cli\u003ePharmaceutical development: This reagent is used to synthesize new drug compounds by facilitating efficient bond formation between functional groups.\u003c\/li\u003e\n\u003cli\u003eBiochemical studies: Its ability to form stable bonds makes it suitable for modifying biomolecules in biochemical experiments.\u003c\/li\u003e\n\u003cli\u003eIndustrial chemical production: TCI E1306 supports the creation of industrial chemicals by enabling precise and controlled chemical reactions.\u003c\/li\u003e\n\u003cli\u003eAnalytical chemistry applications: It is used in analytical processes to ensure accurate and reproducible results in chemical analysis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 333717-40-1\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Synthetic Reagents \u0026gt; Coupling [Synthetic Reagents]\u003c\/li\u003e\n\u003cli\u003ePack sizes: Available in various quantities as per standard laboratory supply\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid, typically in powder or crystalline form\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from moisture and direct sunlight\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eTCI E1306 should be stored in a cool, dry environment to maintain its chemical stability and reactivity. It is recommended to keep the compound in a sealed container to prevent exposure to moisture and air, which can affect its performance. Due to its chemical nature, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. The reagent should not be stored near incompatible substances to avoid any potential chemical interactions. Proper labeling and storage conditions are essential to ensure the safety of laboratory personnel and the integrity of the compound. Regular monitoring of storage conditions will help maintain the quality and effectiveness of TCI E1306 in laboratory settings.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086946644186,"sku":"TCI2510E130629271","price":788000.0,"currency_code":"IDR","in_stock":true},{"title":"5g","offer_id":48086946676954,"sku":"TCI2510E130629272","price":2503000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510E1306.jpg?v=1769180775"},{"product_id":"tci2510f072630681","title":"TCI F0726 164298-23-1 Fluoro-N,N,N',N'-tetramethylformamidinium Hexafluorophosphate","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI F0726 is Fluoro-N,N,N',N'-tetramethylformamidinium Hexafluorophosphate, a coupling reagent widely known by the abbreviation TFFH. Unlike uronium- or phosphonium-based coupling reagents that operate through active esters, this reagent converts a carboxylic acid group into an acyl fluoride in situ. The acyl fluoride is an activated species reactive enough to form an amide bond, yet far more resistant to hydrolysis than the corresponding acyl chloride. This makes handling at the bench considerably more forgiving and results easier to reproduce across runs.\u003c\/p\u003e\n\u003cp\u003eThe advantage that makes this reagent a preferred choice lies in its ability to overcome difficult couplings. The acyl fluoride is small in size, so steric hindrance is reduced, which makes it especially useful for amino acids bearing bulky side chains such as valine and isoleucine derivatives and quaternary amino acids. The reagent also does not generate guanidinylation side products on free amines, a problem that occasionally arises with uronium reagents. In addition, TFFH performs well with amino acids containing sensitive functional groups, including arginine, because activation proceeds rapidly and minimizes lactam formation.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this reagent is typically used in peptide chemistry and chemical biology settings where amide bond formation is the central transformation. It suits academic research groups, pharmaceutical development laboratories, and synthesis facilities that prepare peptide sequences or small-molecule amides. Workers reach for it particularly when standard coupling conditions have already been attempted and a sterically demanding or side-reaction-prone residue requires a more robust activation route.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSolid-phase peptide synthesis: the in situ acyl fluoride route drives couplings to completion on resin-bound sequences where conventional active ester chemistry stalls or gives incomplete conversion.\u003c\/li\u003e\n\u003cli\u003eCoupling of sterically hindered amino acids: the compact acyl fluoride intermediate reduces steric congestion, making it effective for valine, isoleucine, and quaternary amino acid derivatives that resist standard reagents.\u003c\/li\u003e\n\u003cli\u003eArginine-containing sequence assembly: rapid activation limits the residence time of the activated species and thereby minimizes lactam formation, a common side reaction with this residue.\u003c\/li\u003e\n\u003cli\u003eSynthesis involving free amine substrates: because the reagent produces no guanidinylation by-products on free amines, it avoids a side reaction that complicates purification when uronium reagents are used.\u003c\/li\u003e\n\u003cli\u003eGeneral amide bond formation in chemical biology: the greater hydrolytic stability of acyl fluorides compared with acyl chlorides gives more forgiving handling and more reproducible yields between batches.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 164298-23-1\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Peptide Chemistry\u003c\/li\u003e\n\u003cli\u003eChemical name: Fluoro-N,N,N',N'-tetramethylformamidinium Hexafluorophosphate (TFFH)\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in standard TCI catalogue pack sizes; please confirm the required quantity when ordering\u003c\/li\u003e\n\u003cli\u003eStorage: keep in a tightly closed container under the conditions stated on the manufacturer label\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the container tightly closed in a cool, dry place, away from moisture and from sources of heat or ignition, following the conditions given on the manufacturer label and safety data sheet. Because the reagent generates a moisture-sensitive activated species during use, keep the container sealed when not in use and weigh out portions promptly to limit exposure to humid air. Use the original manufacturer container or a compatible tightly sealed glass vessel, clearly labelled. Handle inside a fume hood with appropriate personal protective equipment, including safety glasses, gloves, and a laboratory coat, and avoid contact with skin, eyes, and inhalation of any dust. 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