{"title":"Protecting Agents for Hydroxy and Amino Groups [Nucleic Acid Synthesis]","description":"\u003cp\u003e\u003cstrong\u003eProtecting Agents for Hydroxy and Amino Groups [Nucleic Acid Synthesis]\u003c\/strong\u003e — berisi reagen silil klorida, asil klorida, dan senyawa pelindung lain yang dipakai untuk melindungi gugus hidroksil atau amino pada nukleosida sebelum tahap sintesis oligonukleotida. Gugus pelindung ini bersifat sementara dan dapat dilepas kembali secara selektif pada kondisi reaksi tertentu tanpa merusak bagian molekul lainnya.\u003c\/p\u003e\u003cp\u003eReagen pada kategori ini dipakai pada tahap awal sintesis oligonukleotida untuk memasang gugus pelindung sementara, seperti gugus tert-butildimetilsilil pada hidroksil 2'\/5' atau gugus asil pada gugus amino basa nukleat, sebelum tahap kopling fosforamidit. Kimiawan asam nukleat memilih kombinasi gugus pelindung yang saling ortogonal agar dapat dilepas secara bertahap dan selektif tanpa mengganggu gugus fungsi lain pada rantai oligonukleotida.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510a0082128\"\u003eTCI A0082 75-36-5 Acetyl Chloride\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c030614357\"\u003eTCI C0306 75-77-4 Chlorotrimethylsilane\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b12236402\"\u003eTCI B1223 58479-61-1 tert-Butyldiphenylchlorosilane\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c030814360\"\u003eTCI C0308 76-83-5 Trityl Chloride\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b11516291\"\u003eTCI B1151 57842-27-0 1,3-Benzodithiolylium Tetrafluoroborate [Hydroxyl-Protecting Agent]\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c083215121\"\u003eTCI C0832 4122-68-3 4-Chlorophenoxyacetyl Chloride\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510b09956060\"\u003eTCI B0995 18162-48-6 tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent]\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510d129321005\"\u003eTCI D1293 4637-24-5 N,N-Dimethylformamide Dimethyl Acetal\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan jenis gugus pelindung yang kompatibel dengan strategi deproteksi bertahap, kemurnian reagen klorosilan atau klorida asam yang sensitif terhadap kelembapan, serta kemasan kedap air dan uap lembap. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Nucleic Acid Chemistry, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-phosphorylating-agents-and-phosphorothioating-agents-nucleic-acid-synthesis\"\u003ePhosphorylating Agents and Phosphorothioating Agents [Nucleic Acid Synthesis]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-coupling-activators-and-condensing-agents-nucleic-acid-synthesis\"\u003eCoupling Activators and Condensing Agents [Nucleic Acid Synthesis]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-nucleoside-phosphoramidites-nucleic-acid-synthesis\"\u003eNucleoside Phosphoramidites [Nucleic Acid Synthesis]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-peptide-nucleic-acid-pna-monomers\"\u003ePeptide Nucleic Acid (PNA) Monomers\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-sulfur-transfer-reagents-nucleic-acid-synthesis\"\u003eSulfur Transfer Reagents [Nucleic Acid Synthesis]\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-nucleic-acid-chemistry\"\u003eNucleic Acid Chemistry\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510c083215121","title":"TCI C0832 4122-68-3 4-Chlorophenoxyacetyl Chloride","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI C0832 4-Chlorophenoxyacetyl Chloride (CAS 4122-68-3) is a reactive aromatic acyl chloride supplied in 25 g and 100 g packs. It rapidly acylates amines, alcohols, and phenols to install the 4-chlorophenoxyacetyl motif, a structural fragment frequently encountered in agrochemical intermediates. The reagent is also useful for analytical derivatisation of hydroxyl- and amino-containing analytes and for Friedel–Crafts acylation of suitable aromatic substrates. Because it hydrolyses on contact with moisture and releases corrosive hydrogen chloride, handle it with dry glassware in a fume hood and store it tightly closed under moisture-free conditions.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48086032285914,"sku":"TCI2510C083215121","price":2025000.0,"currency_code":"IDR","in_stock":true},{"title":"100g","offer_id":48086032318682,"sku":"TCI2510C083215122","price":6100000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C0832.jpg?v=1767095860"},{"product_id":"tci2510d129321005","title":"TCI D1293 4637-24-5 N,N-Dimethylformamide Dimethyl Acetal","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI D1293 N,N-Dimethylformamide Dimethyl Acetal, commonly abbreviated as DMF-DMA, is a versatile organic synthesis reagent built on a formamide framework bearing two methoxy groups on the acetal carbon atom. It belongs to the family of non-heterocyclic building blocks and is widely recognised as a key reagent for introducing a one-carbon unit into a target molecule. In synthetic laboratories, DMF-DMA is highly valued for its ability to convert compounds containing active hydrogen into enaminones or amidines — intermediates that serve as gateways to the construction of the many heterocyclic ring systems that matter in medicinal chemistry.\u003c\/p\u003e\n\u003cp\u003eThe properties that make this reagent such a frequent choice are its high yet well-directed reactivity, together with the ease of using it without requiring a complicated catalyst system. DMF-DMA acts both as a source of the dimethylaminomethylene group and as a mild methylating agent for carboxylic acid functionalities, so a single reagent can serve several distinct classes of transformation. This dual capability simplifies reagent inventories and shortens route planning, since one bottle covers formylation-equivalent chemistry, amidine formation and gentle ester preparation within the same workflow.\u003c\/p\u003e\n\u003cp\u003eThe reagent is supplied as a liquid that is highly sensitive to moisture; contact with water hydrolyses it and reduces reaction effectiveness. For this reason, the quality of the results obtained depends strongly on moisture-free handling technique. In Indonesian laboratories this makes DMF-DMA a reagent typically reserved for synthetic and medicinal chemistry groups equipped for anhydrous work, where it is dispensed under inert conditions in university research laboratories, pharmaceutical R\u0026amp;D units and contract synthesis facilities carrying out heterocycle construction.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eEnaminone synthesis — DMF-DMA converts substrates bearing active methylene or active hydrogen centres into enaminones cleanly, giving reliable access to versatile intermediates without complicated catalyst systems.\u003c\/li\u003e\n\u003cli\u003eHeterocyclic ring construction — the enaminone and amidine intermediates generated by this reagent act as direct precursors to the many heterocyclic scaffolds required throughout medicinal chemistry programmes.\u003c\/li\u003e\n\u003cli\u003eAmidine formation — the reagent transfers its dimethylaminomethylene unit to suitable nitrogen-containing substrates, delivering amidine products through a single, well-directed and readily controlled transformation step.\u003c\/li\u003e\n\u003cli\u003eOne-carbon unit introduction — DMF-DMA serves as a dependable source of a single carbon atom for building block elaboration, extending molecular frameworks in non-heterocyclic building block chemistry.\u003c\/li\u003e\n\u003cli\u003eMild esterification of carboxylic acids — acting as a gentle methylating agent, the reagent converts carboxylic acid groups without the harsh conditions that more aggressive methylating reagents demand.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 4637-24-5\u003c\/li\u003e\n\u003cli\u003eProduct code: D1293\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Building Blocks \u0026gt; Non-Heterocyclic Building Blocks\u003c\/li\u003e\n\u003cli\u003ePhysical form: liquid\u003c\/li\u003e\n\u003cli\u003eStorage note: highly moisture sensitive; store under strictly anhydrous conditions\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in the standard TCI catalogue pack sizes for this item\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the reagent in its original tightly sealed container, kept in a cool, dry and well-ventilated area away from sources of ignition and from any incompatible materials. Because DMF-DMA hydrolyses on contact with water, the container should be protected from atmospheric moisture at all times; an inert gas blanket and a desiccated storage cabinet are appropriate. Dispense using dry glassware and dry syringe or cannula technique, and reseal immediately after use to limit air ingress. Handle inside a functioning fume hood while wearing safety glasses, chemically resistant gloves and a laboratory coat. Consult the manufacturer's safety data sheet before first use and follow institutional waste disposal procedures.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25mL","offer_id":48086432907482,"sku":"TCI2510D129321005","price":760000.0,"currency_code":"IDR","in_stock":true},{"title":"100mL","offer_id":48086432940250,"sku":"TCI2510D129321006","price":1997000.0,"currency_code":"IDR","in_stock":true},{"title":"500mL","offer_id":48086432973018,"sku":"TCI2510D129321007","price":5876000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D1293.jpg?v=1767102833"},{"product_id":"tci2510d161221427","title":"TCI D1612 40615-36-9 4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent]","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e4,4'-Dimethoxytrityl Chloride (DMTr-Cl) is a chemical compound widely used as a hydroxyl protecting agent in nucleic acid chemistry. It plays a critical role in the synthesis of nucleotides and nucleic acid molecules by safeguarding hydroxyl groups from unwanted reactions. This compound is essential in biochemical and chemical laboratories, particularly in DNA and RNA research. Its ability to selectively protect hydroxyl groups ensures the accuracy and integrity of molecular structures during complex chemical processes.\u003c\/p\u003e\n\u003cp\u003eDMTr-Cl is valued for its chemical stability and controlled reactivity, making it a reliable choice for protecting functional groups in synthetic reactions. It dissolves easily in organic solvents such as chloroform and DMSO, which simplifies its use in various laboratory applications. The solid form of the compound allows for convenient handling and storage, while its specificity in binding to hydroxyl groups enhances its effectiveness in protecting sensitive molecular structures. These properties make it a preferred reagent in advanced chemical and biochemical experiments.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, DMTr-Cl is commonly used in biochemistry research, especially in nucleotide synthesis, DNA modification, and drug development. Its reliability and effectiveness in protecting hydroxyl groups make it an essential tool for researchers working on nucleic acid-related projects. The compound is widely available and trusted for its consistent performance in laboratory settings, supporting high-quality scientific research and development.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eNucleotide Synthesis: DMTr-Cl is ideal for protecting hydroxyl groups during the synthesis of nucleotides, ensuring accurate molecular structures.\u003c\/li\u003e\n\u003cli\u003eDNA Modification: It is used to selectively protect hydroxyl groups in DNA molecules, facilitating precise modifications and functional studies.\u003c\/li\u003e\n\u003cli\u003eRNA Research: The compound supports RNA synthesis and modification by preventing unwanted reactions at hydroxyl sites.\u003c\/li\u003e\n\u003cli\u003eDrug Development: DMTr-Cl is employed in the synthesis of nucleotide-based drugs, ensuring stability and specificity in molecular structures.\u003c\/li\u003e\n\u003cli\u003eOrganic Chemistry Reactions: Its controlled reactivity and solubility in organic solvents make it suitable for various synthetic reactions requiring hydroxyl protection.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 40615-36-9\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Nucleic Acid Chemistry\u003c\/li\u003e\n\u003cli\u003ePack sizes: Available in various quantities as per standard laboratory supply\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from moisture and light\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eDMTr-Cl should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in a tightly sealed container to prevent exposure to moisture and air. Avoid direct sunlight and high humidity to ensure the integrity of the material. When handling, use appropriate personal protective equipment such as gloves and safety goggles to minimize exposure. The compound is non-toxic in normal handling conditions but should be treated with care in laboratory settings. Proper storage and handling practices help maintain the effectiveness and safety of the reagent in research applications.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48086450667738,"sku":"TCI2510D161221427","price":1097000.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48086450700506,"sku":"TCI2510D161221428","price":3401000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D1612.jpg?v=1768204889"},{"product_id":"tci2510i011535101","title":"TCI I0115 79-30-1 Isobutyryl Chloride","description":"\u003cp\u003e\u003cstrong\u003eIsobutyryl Chloride\u003c\/strong\u003e (CAS 79-30-1) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eGC Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial 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Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48087355621594,"sku":"TCI2510I011535101","price":816000.0,"currency_code":"IDR","in_stock":true},{"title":"100g","offer_id":48087355654362,"sku":"TCI2510I011535102","price":1153000.0,"currency_code":"IDR","in_stock":true},{"title":"500g","offer_id":48087355687130,"sku":"TCI2510I011535103","price":2727000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510I0115.jpg?v=1767119051"},{"product_id":"tci2510m072138510","title":"TCI M0721 100-07-2 4-Methoxybenzoyl Chloride","description":"\u003cp\u003e\u003cstrong\u003e4-Methoxybenzoyl Chloride\u003c\/strong\u003e (CAS 100-07-2) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eHigh Purity Reagent Grade\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C8H7ClO2\u003c\/li\u003e\n\u003cli\u003eCAS number: 100-07-2\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;99.0%(GC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: M0721\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e p-Anisoyl Chloride\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48087558029530,"sku":"TCI2510M072138510","price":1041000.0,"currency_code":"IDR","in_stock":true},{"title":"100g","offer_id":48087558062298,"sku":"TCI2510M072138511","price":3064000.0,"currency_code":"IDR","in_stock":true},{"title":"500g","offer_id":48087558095066,"sku":"TCI2510M072138512","price":8741000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510M0721.jpg?v=1767123553"},{"product_id":"tci2510m079038618","title":"TCI M0790 14470-28-1 4-Methoxytrityl Chloride [Hydroxyl Protecting Agent]","description":"\u003cp\u003e\u003cstrong\u003e4-Methoxytrityl Chloride [Hydroxyl Protecting Agent]\u003c\/strong\u003e (CAS 14470-28-1) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eHPLC Grade\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C20H17ClO\u003c\/li\u003e\n\u003cli\u003eCAS number: 14470-28-1\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(HPLC)(T)\u003c\/li\u003e\n\u003cli\u003eTCI product code: M0790\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e 4-Monomethoxytrityl Chloride\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25g","offer_id":48087563665626,"sku":"TCI2510M079038618","price":3008000.0,"currency_code":"IDR","in_stock":true},{"title":"250g","offer_id":48087563698394,"sku":"TCI2510M079038619","price":18804000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510M0790.jpg?v=1768205730"},{"product_id":"tci2510n040443137","title":"TCI N0404 3958-60-9 2-Nitrobenzyl Bromide","description":"\u003cp\u003e\u003cstrong\u003e2-Nitrobenzyl Bromide\u003c\/strong\u003e (CAS 3958-60-9) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eGC Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C7H6BrNO2\u003c\/li\u003e\n\u003cli\u003eCAS number: 3958-60-9\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(GC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: N0404\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e alpha-Bromo-2-nitrotoluene\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout 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