{"title":"Protein Structural Analysis","description":"\u003cp\u003e\u003cstrong\u003eProtein Structural Analysis\u003c\/strong\u003e — mencakup reagen fluoresen reaktif seperti turunan maleimida, kumarin, dan bromobimana yang berikatan selektif dengan gugus tiol atau amina pada protein. Kelompok ini dipakai untuk menandai residu asam amino spesifik guna mempelajari struktur dan konformasi protein.\u003c\/p\u003e\u003cp\u003eProtein Structural Analysis reagents digunakan peneliti biokimia dan biologi struktural untuk melabeli residu sistein atau lisin pada protein sebelum dianalisis dengan spektrofluorometri, elektroforesis, atau spektrometri massa. Senyawa seperti N-(1-Pyrenyl)maleimide dan Bromobimane membantu mengamati perubahan lipatan protein serta aksesibilitas gugus tiol dalam kondisi eksperimen berbeda.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510b422010406\"\u003eTCI B4220 71418-44-5 Bromobimane\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510c247917256\"\u003eTCI C2479 92557-80-7 5-Carboxyfluorescein N-Succinimidyl Ester\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510s096050600\"\u003eTCI S0960 96735-88-5 N-Succinimidyl 7-Hydroxy-4-methylcoumarin-3-acetate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510f002629702\"\u003eTCI F0026 3326-32-7 Fluorescein 5-Isothiocyanate (isomer I)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510s086750508\"\u003eTCI S0867 150321-92-9 N-Succinimidyl 7-Methoxycoumarin-3-carboxylate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510f078330747\"\u003eTCI F0783 18861-78-4 Fluorescein 6-Isothiocyanate (isomer II)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510s086650506\"\u003eTCI S0866 134471-24-2 N-Succinimidyl 7-Hydroxycoumarin-3-carboxylate\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510f081030783\"\u003eTCI F0810 75350-46-8 Fluorescein-5-maleimide (contains 2% N,N-Dimethylformamide at maximum)\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePerhatikan spesifisitas gugus reaktif label, misalnya maleimida untuk tiol atau ester NHS untuk amina, serta karakteristik panjang gelombang eksitasi-emisi agar sesuai dengan instrumen deteksi yang tersedia. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Fluorescent Labels, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-fluorescent-indicators-and-fluorescent-probes\"\u003eFluorescent Indicators and Fluorescent Probes\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-donors-and-acceptors-for-fret\"\u003eDonors and Acceptors for FRET\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-fluorescence-quenchers\"\u003eFluorescence Quenchers\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l4-fluorescent-labels\"\u003eFluorescent Labels\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510c247917256","title":"TCI C2479 92557-80-7 5-Carboxyfluorescein N-Succinimidyl Ester","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003e5-Carboxyfluorescein N-Succinimidyl Ester (CFSE) is a fluorescent compound widely used in biomedical research and molecular biology. It serves as a vital tool for tracking cell proliferation, particularly in immunology and cancer biology studies. This reagent enables researchers to label and monitor the division of cells over time, offering valuable insights into cellular behavior and response mechanisms. Its application is critical in experiments that require precise and reproducible data, making it an essential component in modern laboratory workflows.\u003c\/p\u003e\n\u003cp\u003eCFSE is preferred due to its chemical stability, high reactivity toward cell surface amines, and distinct emission wavelength. These properties ensure reliable fluorescence detection using instruments like flow cytometers, enhancing the accuracy of cell tracking and analysis. Its strong fluorescence and resistance to photobleaching allow for long-term studies without significant loss of signal intensity. Additionally, its rapid reaction kinetics and ability to maintain fluorescence after activation make it highly practical for repeated use in various experimental setups.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, CFSE is commonly used in molecular biology and immunology research. It supports studies on immune cell dynamics, tumor progression, and cellular responses to stimuli. Researchers in Indonesia rely on CFSE to generate high-quality data for both academic and applied research, contributing to advancements in biotechnology and life sciences. Its utility spans across different research institutions, ensuring its relevance in the scientific community.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eCell proliferation studies benefit from CFSE due to its ability to label and track cell division over time, providing accurate data on cell cycle dynamics.\u003c\/li\u003e\n\u003cli\u003eImmunology research utilizes CFSE to monitor immune cell activation and differentiation, helping to understand immune responses in various disease models.\u003c\/li\u003e\n\u003cli\u003eFlow cytometry applications rely on CFSE for its distinct fluorescence properties, enabling precise quantification of labeled cells in complex mixtures.\u003c\/li\u003e\n\u003cli\u003eCancer biology experiments use CFSE to study tumor cell growth and response to therapeutic agents, offering insights into treatment efficacy.\u003c\/li\u003e\n\u003cli\u003eMolecular biology labs apply CFSE in tracking cell lineage and migration, supporting research on cellular behavior under different experimental conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 92557-80-7\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Antibodies \u0026gt; Antibody Supplementary Products\u003c\/li\u003e\n\u003cli\u003ePack sizes: Available in various quantities as per supplier specifications\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid or powder, depending on packaging\u003c\/li\u003e\n\u003cli\u003eStorage note: Store at 2–8°C in a cool, dry place away from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eCFSE should be stored at 2–8°C in a cool, dry place, away from direct light to maintain its chemical stability and fluorescence properties. It is recommended to use airtight containers to prevent moisture exposure, which could affect its reactivity. When handling, ensure proper laboratory safety practices are followed, including the use of gloves and protective eyewear. Avoid prolonged exposure to heat or UV light to prevent degradation. CFSE is generally stable under standard laboratory conditions but should be used promptly after opening to ensure optimal performance. Always follow standard operating procedures for handling fluorescent reagents to maintain data integrity and safety.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"20mg","offer_id":48086128394458,"sku":"TCI2510C247917256","price":6269000.0,"currency_code":"IDR","in_stock":true},{"title":"100mg","offer_id":48086128427226,"sku":"TCI2510C247917257","price":20687000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510C2479.jpg?v=1767098402"},{"product_id":"tci2510f078330747","title":"TCI F0783 18861-78-4 Fluorescein 6-Isothiocyanate (isomer II)","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI F0783 Fluorescein 6-Isothiocyanate (isomer II) is a fluorescent labelling reagent widely known in molecular biology and biochemistry laboratories, commonly referred to as FITC. The compound consists of a fluorescein core that emits bright green fluorescence when excited by blue light, combined with an isothiocyanate group that acts as a reactive anchor toward amine functionalities. Its role in the laboratory is to link an easily detected optical signal to biological molecules such as proteins, antibodies, peptides, or oligosaccharides, so that the presence and distribution of those molecules can be observed directly.\u003c\/p\u003e\n\u003cp\u003eThe characteristics that make this reagent a preferred choice are the combination of strong fluorescence output and selective labelling reactivity. The isothiocyanate group reacts with primary amines, particularly free amino groups at chain termini as well as on lysine side chains, forming a thiourea linkage that is covalently stable and not readily lost during washing steps. Offering this product as a single isomer, namely isomer II, is an important advantage, because labelling with an isomer mixture can produce heterogeneous conjugates and complicate reproducibility between batches. A single isomer supports more consistent conjugation chemistry and more comparable results from one preparation to the next.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this reagent is typically used in university research groups, biochemistry and molecular biology teaching laboratories, and analytical service units that prepare their own fluorescent conjugates rather than purchasing ready-made labelled reagents. It is drawn on where fluorescence microscopy, flow cytometry, or fluorescence-based detection is part of the routine workflow, and where glycoscience and chemical biology studies require biological molecules to be tagged with a visible optical reporter before observation.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eProtein and antibody labelling, because the isothiocyanate group couples covalently to primary amines on lysine residues and chain termini, producing stable fluorescent conjugates that survive repeated washing.\u003c\/li\u003e\n\u003cli\u003eFluorescence microscopy of cells and tissues, since the fluorescein core emits bright green fluorescence under blue-light excitation and is readily visualised with standard filter configurations used for FITC.\u003c\/li\u003e\n\u003cli\u003eFlow cytometry sample preparation, where labelled antibodies and binding proteins give a strong optical signal that allows individual cells to be distinguished and counted reliably.\u003c\/li\u003e\n\u003cli\u003eGlycoscience research on oligosaccharides and glycoconjugates, in which amine-bearing sugar derivatives are tagged so that their presence and distribution can be tracked during separation and detection.\u003c\/li\u003e\n\u003cli\u003ePeptide labelling for binding and localisation studies, because the single-isomer format gives more homogeneous conjugates and improves reproducibility between preparations compared with isomer mixtures.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 18861-78-4\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Chemical Biology \u0026gt; Glycoscience\u003c\/li\u003e\n\u003cli\u003eProduct code: F0783\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in the pack sizes listed on this product page\u003c\/li\u003e\n\u003cli\u003eStorage note: store under the conditions stated on the manufacturer's label, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the reagent in its original tightly closed container, protected from light, since fluorescein derivatives are light sensitive and the isothiocyanate group is reactive toward moisture and amines. Amber glass vials or containers wrapped in foil are suitable, and the container should be allowed to reach room temperature before opening to limit condensation. Handle the solid in a well-ventilated area or fume hood while wearing gloves, safety glasses, and a laboratory coat, and avoid contact with skin, eyes, and inhalation of dust. Prepare working solutions fresh where possible, keep them shielded from light during use, and consult the manufacturer's safety data sheet before handling and for waste disposal.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"100mg","offer_id":48087031578842,"sku":"TCI2510F078330747","price":9135000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510F0783.jpg?v=1767113860"},{"product_id":"tci2510f081030783","title":"TCI F0810 75350-46-8 Fluorescein-5-maleimide (contains 2% N,N-Dimethylformamide at maximum)","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eTCI F0810 Fluorescein-5-maleimide is a fluorescent labeling reagent designed specifically for tagging thiol groups on proteins, peptides, and other biomolecules. The molecule combines fluorescein, one of the most classical and widely used fluorophores in the life sciences, with a maleimide group that reacts selectively with free sulfhydryl groups. The Michael addition reaction between the maleimide and a thiol proceeds rapidly under near-neutral conditions and produces a stable thioether bond, allowing researchers to attach a fluorescent marker to specific cysteine residues without disturbing amine groups or other functional groups on the biomolecule.\u003c\/p\u003e\n\u003cp\u003eThe advantages that make this reagent a frequent choice are the selectivity of its reaction and the brightness of its fluorophore. Thiol selectivity permits labeling at a defined position, an essential requirement in studies of protein structure, measurements of distance between residues, and monitoring of conformational change. Fluorescein itself has a high absorption coefficient and strong green emission within an excitation range available on nearly every fluorescence microscope, microplate reader, and flow cytometer, so that specialised instrumentation is not required to detect the labeled product.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this reagent is typically used in university and institutional research settings where protein chemistry, biochemistry, and molecular biology work is carried out. Because fluorescein is detectable on the standard fluorescence instrumentation already present in most local facilities, the reagent fits readily into existing workflows for protein characterisation, conjugate preparation, and fluorescence-based assay development without additional equipment investment.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSite-specific protein labeling: the maleimide group reacts selectively with free cysteine residues, allowing a fluorescent tag to be placed at one defined position on the protein without modifying amine groups.\u003c\/li\u003e\n\u003cli\u003eProtein structure studies: because labeling occurs at a defined residue, the attached fluorescein serves as a reporter for investigating structural organisation and the spatial arrangement of a protein of interest.\u003c\/li\u003e\n\u003cli\u003eDistance measurement between residues: defined-position labeling supports experiments that determine the separation between selected residues, where the exact placement of the fluorophore is critical to interpretation.\u003c\/li\u003e\n\u003cli\u003eConformational change monitoring: a fluorescein tag attached at a specific cysteine reports changes in the local environment, making it suitable for following conformational transitions in proteins under different conditions.\u003c\/li\u003e\n\u003cli\u003eFluorescence detection workflows: the high absorption coefficient and strong green emission of fluorescein allow labeled products to be read on ordinary fluorescence microscopes, microplate readers, and flow cytometers.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 75350-46-8\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Antibodies \u0026gt; Antibody Supplementary Products\u003c\/li\u003e\n\u003cli\u003eProduct name: Fluorescein-5-maleimide (contains 2% N,N-Dimethylformamide at maximum)\u003c\/li\u003e\n\u003cli\u003ePack sizes: please refer to the available packaging options listed for this catalogue item\u003c\/li\u003e\n\u003cli\u003eStorage: store according to the conditions stated on the manufacturer's label and product documentation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the reagent in its original tightly closed container under the conditions specified on the manufacturer's label, protected from light, since fluorescein-based fluorophores are sensitive to photodegradation and prolonged light exposure may reduce labeling performance. Keep the container in a dry location and allow it to reach room temperature before opening to limit moisture condensation, which can hydrolyse the maleimide group. Handle the material in a well-ventilated area or fume hood, using gloves, safety glasses, and a laboratory coat, and note that the product contains a maximum of 2% N,N-Dimethylformamide. Consult the safety data sheet supplied by the manufacturer before use, and dispose of residues in accordance with applicable laboratory waste procedures.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"25mg","offer_id":48087033610458,"sku":"TCI2510F081030783","price":5847000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510F0810.jpg?v=1767113868"},{"product_id":"tci2510p036445688","title":"TCI P0364 5624-13-5 Phenylthiohydantoin-aspartic Acid","description":"\u003cp\u003e\u003cstrong\u003ePhenylthiohydantoin-aspartic Acid\u003c\/strong\u003e (CAS 5624-13-5) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eReagent Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C11H10N2O3S\u003c\/li\u003e\n\u003cli\u003eCAS number: 5624-13-5\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;95.0%(T)\u003c\/li\u003e\n\u003cli\u003eTCI product code: P0364\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e 3-Phenyl-2-thiohydantoin-5-acetic Acid; PTH-aspartic Acid\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"100mg","offer_id":48087961534682,"sku":"TCI2510P036445688","price":536000.0,"currency_code":"IDR","in_stock":true},{"title":"1g","offer_id":48087961567450,"sku":"TCI2510P036445689","price":2082000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510P0364.jpg?v=1767133058"},{"product_id":"tci2510p036645690","title":"TCI P0366 4370-90-5 Phenylthiohydantoin-methionine","description":"\u003cp\u003e\u003cstrong\u003ePhenylthiohydantoin-methionine\u003c\/strong\u003e (CAS 4370-90-5) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eHPLC Grade\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C12H14N2OS2\u003c\/li\u003e\n\u003cli\u003eCAS number: 4370-90-5\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(HPLC)(N)\u003c\/li\u003e\n\u003cli\u003eTCI product code: P0366\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e 5-[2-(Methylthio)ethyl]-3-phenyl-2-thiohydantoin; 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