{"title":"Small Molecule Activators [Organoid Culture]","description":"\u003cp\u003e\u003cstrong\u003eSmall Molecule Activators [Organoid Culture]\u003c\/strong\u003e — mencakup hormon steroid, prostaglandin, dan senyawa kecil seperti forskolin yang berperan sebagai sinyal aktivator jalur pensinyalan sel dalam formulasi medium kultur organoid untuk mendorong proliferasi dan diferensiasi sel punca, serta menjaga keseimbangan self-renewal jaringan.\u003c\/p\u003e\u003cp\u003eAktivator molekul kecil seperti dexamethasone, retinoic acid, testosterone, dan heparin sodium dipakai peneliti biologi sel dan pengembangan organoid untuk menyusun medium kultur 3D organ mini seperti usus, hati, atau organoid tumor, mendukung diferensiasi terarah menuju tipe sel spesifik. Kombinasi faktor ini juga digunakan dalam model penyakit dan uji skrining obat berbasis organoid.\u003c\/p\u003e\u003cp\u003eContoh produk dalam koleksi ini: \u003ca href=\"\/en\/products\/tci2510t002750701\"\u003eTCI T0027 58-22-0 Testosterone\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510d196121959\"\u003eTCI D1961 50-02-2 Dexamethasone\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510r006449507\"\u003eTCI R0064 302-79-4 Retinoic Acid\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510f085530848\"\u003eTCI F0855 66575-29-9 Forskolin\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510p188447584\"\u003eTCI P1884 363-24-6 Prostaglandin E2\u003c\/a\u003e, \u003ca href=\"\/en\/products\/tci2510h039332934\"\u003eTCI H0393 9041-08-1 Heparin Sodium Salt from Hog intestine\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003ePilih berdasarkan kemurnian dan sumber biologis (misalnya heparin dari mukosa babi), kelarutan dalam pelarut medium, serta stabilitas senyawa terhadap cahaya dan suhu penyimpanan agar aktivitas biologisnya tetap terjaga. Seluruh produk merupakan produk asli Tokyo Chemical Industry (TCI) Jepang, dengan kemurnian, kemasan, dan kondisi penyimpanan tercantum pada halaman masing-masing item.\u003c\/p\u003e\u003cp\u003eKategori lain yang sejajar di bawah Organoid Culture, sering dipakai bersamaan dalam satu alur kerja laboratorium:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-chemicals-other-organoid-culture\"\u003eChemicals (Other) [Organoid Culture]\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/tci-l4-small-molecule-inhibitors-organoid-culture\"\u003eSmall Molecule Inhibitors [Organoid Culture]\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eKembali ke \u003ca href=\"\/en\/collections\/tci-l3-organoid-culture\"\u003eOrganoid Culture\u003c\/a\u003e. Untuk pengadaan volume besar, kemasan khusus, atau grade tertentu, hubungi tim AMI Scientific — distributor resmi TCI Japan di Indonesia — untuk pengecekan ketersediaan dan lead time langsung ke Jepang.\u003c\/p\u003e","products":[{"product_id":"tci2510d196121959","title":"TCI D1961 50-02-2 Dexamethasone","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eDexamethasone is a synthetic corticosteroid widely used in biomedical and pharmacological research. As a derivative of glucocorticoids, it plays a crucial role in modulating immune responses and metabolic processes within laboratory settings. This compound is particularly valuable in organoid culture studies, where it supports the development and maintenance of human or animal tissue models. Its ability to influence cellular differentiation and create optimal culture environments makes it an essential tool for researchers working with complex biological systems.\u003c\/p\u003e\n\u003cp\u003eDexamethasone is preferred due to its potent anti-inflammatory properties and its capacity to suppress immune responses. These characteristics make it ideal for applications requiring the reduction of inflammation or the inhibition of T-cell activity. Its stability under certain conditions and ease of storage further enhance its utility across various research scales. The compound's versatility allows it to be used in a wide range of experimental designs, from disease modeling to drug testing, making it a staple in modern laboratory practices.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, Dexamethasone is commonly used in research related to autoimmune diseases, cancer, and inflammatory conditions. Its role in developing disease models and testing therapeutic effects has made it a key component in both academic and industrial research. The compound's reliability and consistent performance ensure that it remains a trusted reagent for scientists working in diverse fields of life sciences.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eOrganoid Culture: Dexamethasone supports the development and maintenance of human and animal organoids by modulating cellular differentiation and creating optimal culture environments.\u003c\/li\u003e\n\u003cli\u003eDisease Modeling: Its anti-inflammatory properties make it suitable for creating in vitro models of inflammatory and autoimmune diseases for research and drug development.\u003c\/li\u003e\n\u003cli\u003eImmunomodulation Studies: The compound's ability to suppress immune responses is ideal for experiments involving T-cell inhibition and immune system modulation.\u003c\/li\u003e\n\u003cli\u003eDrug Efficacy Testing: Dexamethasone is used to assess the effects of pharmaceutical compounds in controlled environments, particularly in inflammation-related conditions.\u003c\/li\u003e\n\u003cli\u003eTissue Engineering: It aids in the cultivation of engineered tissues by influencing cellular behavior and promoting the formation of functional tissue structures.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 50-02-2\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Cell Culture \u0026gt; Organoid Culture\u003c\/li\u003e\n\u003cli\u003ePack sizes: Available in various quantities as per standard laboratory supply options\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid powder\u003c\/li\u003e\n\u003cli\u003eStorage note: Store at controlled room temperature, away from moisture and light\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eDexamethasone should be stored in a cool, dry place away from direct sunlight and moisture to maintain its stability and potency. It is recommended to use airtight containers to prevent contamination and degradation. In laboratory settings, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safety during preparation and use. Proper labeling of containers is essential for traceability and safe handling. Due to its chemical nature, it should be kept out of reach of children and stored in a secure location. Regular monitoring of storage conditions ensures the compound remains effective for research applications.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48086485663962,"sku":"TCI2510D196121959","price":2053000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510D1961.jpg?v=1769144013"},{"product_id":"tci2510f085530848","title":"TCI F0855 66575-29-9 Forskolin","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eForskolin is an active compound derived from the plant *Coleus forskohlii*, widely used in biomedical and life science research. It is a key reagent in laboratory settings due to its ability to enhance cyclic AMP (cAMP) production in cells. This property makes it essential for studying cellular signaling pathways and cell differentiation. Forskolin plays a critical role in organoid culture, where it helps researchers mimic the structure and function of organ tissues. Its versatility supports a wide range of experimental applications, making it a valuable tool in modern biological research.\u003c\/p\u003e\n\u003cp\u003eForskolin is chemically stable and soluble in organic solvents, which facilitates its use in various experimental protocols. These characteristics contribute to its reliability and ease of handling in laboratory environments. The compound’s relatively high safety profile when used in appropriate quantities ensures it is suitable for routine laboratory work. Its ability to modulate intracellular signaling pathways makes it a preferred choice for studies involving cell differentiation, tissue regeneration, and therapeutic development. Its consistent performance and predictable behavior further enhance its appeal in research settings.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, Forskolin is commonly used in applied research, particularly in biomedical and life science fields. It supports studies on organoid development, cellular signaling, and therapeutic applications. Researchers in Indonesia rely on Forskolin for its effectiveness and reliability in experimental procedures, making it a staple in many research facilities across the country.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eOrganoid Culture: Forskolin is widely used to stimulate cAMP production, essential for maintaining and differentiating organoid cells.\u003c\/li\u003e\n\u003cli\u003eCellular Signaling Studies: Its ability to modulate intracellular signaling pathways makes it ideal for investigating signal transduction mechanisms.\u003c\/li\u003e\n\u003cli\u003eTissue Regeneration Research: Forskolin supports studies on tissue repair and regeneration by influencing cell differentiation processes.\u003c\/li\u003e\n\u003cli\u003eDrug Development: It is utilized in screening compounds that affect cAMP levels, aiding in the discovery of new therapeutic agents.\u003c\/li\u003e\n\u003cli\u003eStem Cell Differentiation: Forskolin helps in the differentiation of stem cells into specialized cell types, supporting regenerative medicine research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 66575-29-9\u003c\/li\u003e\n\u003cli\u003eCategory: Life Science \u0026gt; Cell Culture \u0026gt; Organoid Culture\u003c\/li\u003e\n\u003cli\u003ePack sizes: Available in various quantities as per supplier specifications\u003c\/li\u003e\n\u003cli\u003ePhysical form: Solid powder\u003c\/li\u003e\n\u003cli\u003eStorage note: Store in a cool, dry place away from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eForskolin should be stored in a cool, dry place, away from direct light to maintain its chemical stability. It is recommended to use airtight containers to prevent moisture absorption and contamination. Due to its solubility in organic solvents, it is important to handle it with care during preparation and experimentation. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when working with this compound. Proper labeling of containers is essential to ensure safe handling and prevent accidental exposure. Regular monitoring of storage conditions ensures the compound remains effective for research applications.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"10mg","offer_id":48087040196826,"sku":"TCI2510F085530848","price":2053000.0,"currency_code":"IDR","in_stock":true},{"title":"50mg","offer_id":48087040229594,"sku":"TCI2510F085530849","price":7111000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510F0855.jpg?v=1767113912"},{"product_id":"tci2510p188447584","title":"TCI P1884 363-24-6 Prostaglandin E2","description":"\u003cp\u003e\u003cstrong\u003eProstaglandin E2\u003c\/strong\u003e (CAS 363-24-6) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eHPLC Grade\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C20H32O5\u003c\/li\u003e\n\u003cli\u003eCAS number: 363-24-6\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(HPLC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: P1884\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSynonyms:\u003c\/strong\u003e PGE2\u003c\/p\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1mg","offer_id":48088082350298,"sku":"TCI2510P188447584","price":1153000.0,"currency_code":"IDR","in_stock":true},{"title":"10mg","offer_id":48088082383066,"sku":"TCI2510P188447585","price":7392000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510P1884.jpg?v=1767135389"},{"product_id":"tci2510t002750701","title":"TCI T0027 58-22-0 Testosterone","description":"\u003cp\u003e\u003cstrong\u003eTestosterone\u003c\/strong\u003e (CAS 58-22-0) is a high-quality chemical from TCI, supplied as \u003cstrong\u003eGC Grade \/ for Synthesis\u003c\/strong\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSpecifications:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eMolecular formula: C19H28O2\u003c\/li\u003e\n\u003cli\u003eCAS number: 58-22-0\u003c\/li\u003e\n\u003cli\u003ePurity: \u0026gt;98.0%(GC)\u003c\/li\u003e\n\u003cli\u003eTCI product code: T0027\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAvailable from \u003cstrong\u003eAMI Scientific\u003c\/strong\u003e, the authorised TCI distributor in Indonesia. \u003cstrong\u003eContact us for pricing and stock availability\u003c\/strong\u003e — we ship throughout Indonesia.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"1g","offer_id":48088281448666,"sku":"TCI2510T002750701","price":1546000.0,"currency_code":"IDR","in_stock":true},{"title":"10g","offer_id":48088281481434,"sku":"TCI2510T002750702","price":6943000.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510T0027.jpg?v=1768363081"}],"url":"https:\/\/amiscientific.com\/en\/collections\/tci-l4-small-molecule-activators-organoid-culture.oembed","provider":"AMI Scientific","version":"1.0","type":"link"}