{"product_id":"tci2510b629113129","title":"TCI B6291 289708-48-1 N1,N2-Bis(2,5-dimethyl-1H-pyrrol-1-yl)oxalamide","description":"\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eN1,N2-Bis(2,5-dimethyl-1H-pyrrol-1-yl)oxalamide is an organic compound belonging to the oxalamide family, and in synthesis laboratories it serves as a supporting ligand for transition metal catalysts, particularly copper-based systems. The molecule consists of an oxalamide core — two directly linked amide groups — bearing two 2,5-dimethylpyrrole rings attached at the nitrogen atoms. This arrangement forms a clamp-like framework capable of binding a metal center in a bidentate fashion and stabilizing it throughout the catalytic cycle. The presence of a ligand of this kind is often the deciding factor in whether a cross-coupling reaction proceeds smoothly or stalls partway through.\u003c\/p\u003e\n\u003cp\u003eThe characteristics that make this compound a preferred choice are the combination of electron density at the amide groups and the controlled steric effect of the two dimethylpyrrole substituents. The methyl groups at positions 2 and 5 of the pyrrole rings provide spatial protection around the metal center, thereby reducing catalyst aggregation and undesirable decomposition pathways. The oxalamide framework itself is relatively rigid, so the geometry of the metal–ligand complex is better defined than with flexible amine ligands. As a solid, the compound is easy to weigh out and introduce into a reaction.\u003c\/p\u003e\n\u003cp\u003eIn Indonesian laboratories, this ligand typically appears in university and institutional research groups working on organic synthesis methodology, where copper-catalysed coupling routes are explored on a small scale. Its solid form suits the practical realities of local bench work: weighing on an analytical balance, transfer into a reaction vessel, and use in modest quantities per experiment. It is generally purchased in research-scale packs rather than bulk, since a single project consumes only small amounts.\u003c\/p\u003e\n\u003ch3\u003eLaboratory Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eCopper-catalysed cross-coupling reactions — the bidentate oxalamide core binds and stabilises the copper centre through the catalytic cycle, helping the reaction reach completion instead of stalling.\u003c\/li\u003e\n\u003cli\u003eLigand screening in methodology development — researchers comparing supporting ligands can include this oxalamide to assess how a rigid framework influences conversion relative to flexible amine ligands.\u003c\/li\u003e\n\u003cli\u003eCatalyst stabilisation studies — the 2,5-dimethyl substitution provides steric shielding around the metal centre, making this compound useful for investigating how bulk suppresses catalyst aggregation.\u003c\/li\u003e\n\u003cli\u003ePreparation of metal–ligand complexes — the relatively rigid oxalamide backbone yields complexes with better-defined geometry, which is valuable when coordination environment must be controlled deliberately.\u003c\/li\u003e\n\u003cli\u003eSmall-scale synthetic route optimisation — as a weighable solid it is straightforward to dose accurately across repeated trial reactions when tuning catalyst loading and reaction conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBrand: TCI\u003c\/li\u003e\n\u003cli\u003eCAS number: 289708-48-1\u003c\/li\u003e\n\u003cli\u003eCatalogue code: B6291\u003c\/li\u003e\n\u003cli\u003eCategory: Chemistry \u0026gt; Catalysis and Inorganic Chemistry \u0026gt; Ligands (Other) [Catalysis]\u003c\/li\u003e\n\u003cli\u003ePack sizes: available in research-scale packs; please confirm currently listed sizes when ordering\u003c\/li\u003e\n\u003cli\u003ePhysical form: solid\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHandling and Storage\u003c\/h3\u003e\n\u003cp\u003eStore the container tightly closed in a cool, dry place away from direct sunlight, heat sources, and moisture, following the storage conditions stated on the manufacturer's label and safety data sheet. Keep the material in its original container or in a chemically compatible, well-sealed vessel that is clearly labelled with the compound name and CAS number. Handle in a fume hood or a well-ventilated working area, and wear a laboratory coat, safety goggles, and suitable gloves. Use clean, dry spatulas when weighing to avoid contaminating the remaining stock, and close the container immediately after use. Segregate from strong oxidising agents and incompatible chemicals during storage. Consult the safety data sheet before first use and dispose of residues and contaminated materials in accordance with applicable laboratory waste procedures.\u003c\/p\u003e","brand":"TCI","offers":[{"title":"5g","offer_id":48085929033946,"sku":"TCI2510B629113129","price":3817800.0,"currency_code":"IDR","in_stock":true},{"title":"25g","offer_id":48085929066714,"sku":"TCI2510B629113130","price":13222650.0,"currency_code":"IDR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/7156\/8602\/files\/TCI2510B6291_72394b70-4f3d-4ad6-a55b-67e4f4dcbe7d.jpg?v=1767865162","url":"https:\/\/amiscientific.com\/en\/products\/tci2510b629113129","provider":"AMI Scientific","version":"1.0","type":"link"}