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Description
Nepsilon-5-Norbornene-2-yloxycarbonyl-L-lysine Hydrochloride is an unnatural amino acid carrying a strained norbornene handle on the lysine side chain, supplied as an endo/exo mixture. It is widely used in genetic code expansion, where orthogonal tRNA/synthetase pairs incorporate it site-specifically into proteins. The norbornene group then undergoes rapid, catalyst-free inverse electron demand Diels–Alder ligation with tetrazine reagents. TCI supplies this chemical biology reagent in a 25 mg pack size for research use.
