TCI B6524, tert-Butyl Phenylcarbamate (CAS 3422-01-3), is Boc-protected aniline, a fundamental building block in organic synthesis. The carbamate group moderates the reactivity of the aromatic amine, allowing selective transformations elsewhere in the molecule before acidic deprotection restores the free aniline. It is frequently employed as a model substrate in palladium-catalysed amination and C–H functionalisation methodology studies. AMI Scientific offers this reagent in original TCI packaging in 5 g and 25 g sizes.
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- Symerský dkk. (1990). Structures of tert-butyl N-benzoyl-N-phenylcarbamate and tert-butyl N-acetyl-N-phenylcarbamate. Acta Crystallographica Section C Crystal Structure Communications doi:10.1107/s0108270189009200
- Piovan et al. (2011). Enzymatic Kinetic Resolution of tert-Butyl 2-(1-Hydroxyethyl)phenylcarbamate, A Key Intermediate to Chiral Organoselenanes and Organotelluranes. Molecules doi:10.3390/molecules16098098
- Kraehenbuehl et al. (1994). Vapor Pressures of Methyl tert-Butyl Ether, Ethyl tert-Butyl Ether, Isopropyl tert-Butyl Ether, tert-Amyl Methyl Ether, and tert-Amyl Ethyl Ether. Journal of Chemical & Engineering Data doi:10.1021/je00016a026
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