TCI B6608, tert-butyl (5-aminobicyclo[3.1.1]heptan-1-yl)carbamate, is a mono-Boc-protected bicyclic diamine building block. The free primary amine can be acylated, sulfonylated, or reductively alkylated while the second nitrogen remains masked until acidic deprotection. Its rigid bicyclo[3.1.1]heptane core provides a fixed spatial relationship between the two nitrogen handles, useful in three-dimensional scaffold design. AMI Scientific offers this TCI reagent in a 100 mg pack size for medicinal chemistry and organic synthesis laboratories.
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- Chmovzh et al. (2021). tert-Butyl Bis(4′-(Hexyloxy)-[1,1′-biphenyl]-4-yl)carbamate. Molbank doi:10.3390/m1247
- (2009). MILD AND EFFICIENT ONE-POT CURTIUS REARRANGEMENT: PREPARATION OF N-tert-BUTYL ADAMANTANYL-1-YL-CARBAMATE. Organic Syntheses doi:10.15227/orgsyn.086.0113
- (2022). Diasterocontrol Synthesis of Tamiflu Intermediate of Tert- butyl(5-hydroxy-6-(1-ethylpropoxy)-1,2-epoxycyclohex- 3-en-1-yl)carbamate. MALAYSIAN JOURNAL OF CHEMISTRY doi:10.55373/mjchem.v24i2.258
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
![tert-Butyl (5-Aminobicyclo[3.1.1]heptan-1-yl)carbamate (CAS 1049607-15-9) - TCI B6608 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510B6608.jpg?v=1767094016&width=1445)

