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Description
TCI B6959 is 3-[(tert-butoxycarbonyl)amino]benzoic acid, a Boc-protected aminobenzoic acid building block widely used in peptide and medicinal chemistry. Its free carboxylic acid is ready for standard amide coupling, while the Boc group keeps the aromatic amine masked until acidic deprotection. This orthogonality makes it convenient for stepwise assembly of linkers, scaffolds, and analogue libraries. AMI Scientific offers 5 g and 25 g pack sizes; keep the material dry, cool, and away from strong acids and heat.
Scientific References
Kadyrov et al. (2021). Convenient Synthesis of (R)-3-[(tert-Butoxycarbonyl)amino]piperidine and (R)-3-[(tert-Butoxycarbonyl)amino]azepane. Synthesisdoi:10.1055/a-1526-7657
(2012). Discussion Addendum For: Efficient Asymmetric Synthesis of N-tert-Butoxycarbonyl a-Amino Acids using 4-tert-Butoxycarbonyl-5,6-Diphenylmorpholin-2-one:. Organic Synthesesdoi:10.15227/orgsyn.089.0394
IHLE et al. (1996). ChemInform Abstract: Preparation of 4‐Alkyl‐2‐(N‐(tert‐butoxycarbonyl)amino)pyridines by Alkylation, Nucleophilic Addition, and Acylation of 2‐(N‐(tert‐ Butoxycarbonyl)amino)‐4‐picoline.. ChemInformdoi:10.1002/chin.199646162
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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