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TCI

CAS 3496-11-5

N-Carbobenzoxy-L-valine Succinimidyl Ester TCI C2334

N-Carbobenzoxy-L-valine Succinimidyl Ester TCI C2334

Chemical Identity

Other names
N-Cbz-L-valine Succinimidyl Ester · Z-Val-OSu · N-Benzyloxycarbonyl-L-valine Succinimidyl Ester
CAS No.
3496-11-5
Formula
C17H20N2O6
Molecular weight
348.36 g/mol
Purity
>98.0%(HPLC)
Storage
<0°C
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2,5-dioxopyrrolidin-1-yl) (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate
SMILES
CC(C)C(C(=O)ON1C(=O)CCC1=O)NC(=O)OCC2=CC=CC=C2
InChIKey
MFAOBGXYLNLLJE-HNNXBMFYSA-N
MDL
MDL00053547
PubChem
CID 853556
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N-Carbobenzoxy-L-valine Succinimidyl Ester (N-CBZ-L-valine SUC) is a chemical compound widely used in chemical biology, particularly in peptide chemistry. This compound serves as a key reagent in the synthesis of peptides, especially in solid-phase peptide synthesis (SPPS) methods. Its modified structure, featuring a succinimidyl group, enables efficient activation for peptide bond formation. In laboratory settings, it plays a crucial role in the development of bioactive molecules and pharmaceutical research. The compound is valued for its stability and reactivity, making it a reliable choice for various synthetic applications.

The succinimidyl group in N-CBZ-L-valine SUC is highly reactive towards amines, facilitating the formation of peptide bonds with high efficiency. This reactivity ensures that the compound can be used in a variety of peptide synthesis protocols without significant side reactions. Its chemical stability allows it to maintain its structural integrity during synthesis, which is essential for producing high-quality peptides. These properties make it a preferred choice for researchers working in biochemical and pharmacological fields.

In Indonesian laboratories, N-CBZ-L-valine SUC is commonly used by researchers and academic institutions for peptide synthesis and related studies. It is particularly relevant in the development of biomedicinal products and in research involving peptides and proteins. Its application extends to pharmaceutical and biotechnology sectors, supporting innovation in drug discovery and therapeutic development.

  • Solid-phase peptide synthesis (SPPS) benefits from its reactivity and stability, enabling efficient peptide bond formation.
  • Biochemical research utilizes it for the synthesis of bioactive peptides, aiding in the study of protein structure and function.
  • Pharmaceutical development incorporates it in the creation of therapeutic peptides, supporting drug discovery efforts.
  • Biotechnology applications rely on its role in synthesizing peptides for diagnostic and therapeutic purposes.
  • Academic research employs it in peptide chemistry studies, contributing to advancements in molecular biology and pharmacology.

Brand TCI
CAS number 3496-11-5
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes Available in standard laboratory quantities
Physical form Solid
Storage Store in a cool, dry place away from moisture and light

This compound should be stored in a cool, dry environment, away from moisture and direct light to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity, which could affect its reactivity. Proper labeling of storage containers is essential for safe handling and identification. In laboratory settings, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safety during synthesis procedures. Regular monitoring of storage conditions helps maintain the integrity of the compound for consistent results in peptide synthesis experiments.

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