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TCI

CAS 120-83-2

2,4-Dichlorophenol [for Biochemical Research] TCI D3865

2,4-Dichlorophenol [for Biochemical Research] TCI D3865
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Description

TCI D3865 2,4-Dichlorophenol [for Biochemical Research] is a chlorinated phenol derivative prepared for biochemical research purposes while also serving as a non-heterocyclic building block in synthetic chemistry. Its molecule consists of a benzene ring bearing a phenolic hydroxyl group together with two chlorine atoms located at the two and four positions. The presence of these chlorine atoms raises the acidity of the hydroxyl group compared with ordinary phenol, so the compound is readily deprotonated to form a reactive phenoxide. In the laboratory, its principal role is as a starting material for the formation of aryl ethers and as a model compound in environmental studies.

The properties that make this material a preferred choice are the combination of increased acidity, the stability of the aromatic ring, and a clearly defined substitution pattern. Because the two chlorine substituents occupy known positions, reaction outcomes are predictable and the compound behaves consistently as a synthetic intermediate. The phenoxide that forms upon deprotonation can be reacted with alkyl halides or with chloroacetic acid to construct aryloxy derivatives, a route that underpins the synthesis of many agrochemical compounds. The aromatic ring itself remains stable through these transformations, allowing the reactive hydroxyl position to be addressed selectively without disturbing the rest of the structure.

In Indonesian laboratories, this compound is commonly used in biochemical and environmental work as a substrate or standard. Typical contexts include research on microbial degradation, peroxidase and laccase enzyme assays, and studies of chlorinated phenol toxicity. The designation as a grade for biochemical research confirms its suitability for these applications, making it appropriate for university research groups, environmental laboratories, and synthesis laboratories that prepare aryloxy derivatives.

Laboratory Applications

  • Aryl ether synthesis — the increased acidity of the hydroxyl group allows straightforward deprotonation to the phenoxide, which then reacts with alkyl halides to build ether linkages.
  • Aryloxy derivative preparation — reaction of the phenoxide with chloroacetic acid produces aryloxy compounds, the fundamental route on which the synthesis of many agrochemical substances is based.
  • Microbial degradation research — the compound serves as a defined substrate or standard, letting researchers track the breakdown of chlorinated phenols by microorganisms under controlled conditions.
  • Peroxidase and laccase enzyme assays — its well-defined phenolic structure makes it a consistent substrate for measuring the oxidative activity of these enzymes in biochemical studies.
  • Chlorinated phenol toxicity studies — as a model compound in environmental work, it provides a representative chlorinated phenol for investigating toxicity behaviour and related environmental effects.

Specifications

  • Brand: TCI
  • CAS number: 120-83-2
  • Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
  • Grade: for Biochemical Research
  • Chemical class: chlorinated phenol derivative; non-heterocyclic building block
  • Pack sizes: available in the pack sizes offered for this catalogue item
  • Storage: store according to the manufacturer's instructions on the product label

Handling and Storage

Store the container tightly closed in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible materials, following the storage conditions stated by the manufacturer on the product label. Keep the material in its original supplier container or in a chemically compatible, clearly labelled vessel that is resistant to phenolic compounds. Handle the substance in a fume hood and wear appropriate personal protective equipment, including safety goggles, chemical-resistant gloves, and a laboratory coat, since chlorinated phenols can irritate skin, eyes, and the respiratory tract. Avoid the formation of dust during weighing, close the container immediately after use, and consult the manufacturer's safety data sheet before handling, storage, or waste disposal.

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