N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methylglycine TCI F1163

Chemical Identity

Other names: N-Fmoc-N-methylglycine · Fmoc-N-Me-Gly-OH
CAS No.: 77128-70-2
PubChem: CID 688640·SID 354334554
Formula: C18H17NO4
Molecular weight: 311.34 g/mol
Purity: >98.0%(HPLC)(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]acetic acid
SMILES: CN(CC(=O)O)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
InChIKey: ZHKQIADIIYMFOZ-UHFFFAOYSA-N
MDL: MDL00151926

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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methylglycine is a chemical compound widely used in laboratory settings for organic and peptide synthesis applications. This compound plays a crucial role in the formation of ester and amide bonds, particularly in the coupling of amino acids during peptide chain construction. Its versatility makes it an essential reagent in synthetic chemistry, supporting the development of complex molecular structures with high precision. In research and development environments, it is valued for its ability to facilitate efficient and reproducible chemical reactions.

The compound's chemical properties, including its stability and solubility in organic solvents, make it a preferred choice for laboratory use. It dissolves well in solvents such as ethyl acetate and acetone, enabling easy incorporation into various synthetic protocols. Its chemical stability ensures that it remains effective over time, even under normal storage conditions, reducing the risk of degradation and maintaining its reactivity. These characteristics contribute to its reliability in both academic and industrial research settings.

In Indonesian laboratories, this compound is commonly used in organic and peptide chemistry research. Researchers in educational institutions and research centers rely on it for developing new compounds and refining synthesis methods. Its consistent performance and predictable behavior make it a trusted component in the toolkit of chemists working on complex molecular structures and functional group transformations.

TCI brochures (PDF)

Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 22

Related TCI products

Organic synthesis applications benefit from this compound’s ability to form stable ester and amide bonds, essential for constructing complex molecular frameworks.
Peptide chemistry research utilizes it as a key reagent in amino acid coupling reactions, enabling the synthesis of peptides with precise structural integrity.
Structural chemistry studies rely on its predictable reactivity to facilitate controlled chemical transformations and molecular modifications.
Analytical chemistry procedures use it as a reference standard for evaluating reaction efficiency and product purity.
Biochemical research incorporates it in the development of bioactive compounds, supporting the study of molecular interactions and biological activity.

Brand	TCI
CAS number	77128-70-2
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes	Available in various quantities as per standard laboratory supply
Physical form	Solid powder
Storage	Store in a cool, dry place away from moisture and direct sunlight

This compound should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to use airtight containers to protect it from moisture and potential contaminants. Due to its solubility in organic solvents, it should be kept away from incompatible substances to avoid unintended reactions. Standard laboratory safety practices, such as wearing appropriate personal protective equipment, should be followed during handling. Proper labeling of storage containers is essential for safe and efficient access. Regular inspection of storage conditions ensures that the compound remains in optimal condition for use in research applications.

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