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Description
(Fmoc-amino)-PEG6-carboxylic Acid is a chemical compound widely used in biochemical and pharmaceutical research. This compound is a key reagent in PEGylation, a process that involves attaching polyethylene glycol (PEG) chains to biological molecules. Its structure consists of a PEG6 chain linked to an Fmoc-protected amino group, making it highly versatile for molecular modification. This compound is essential for enhancing the stability, solubility, and bioavailability of therapeutic proteins and other biomolecules. Due to its functional versatility, it is a critical component in various biotechnological applications.
The compound's properties make it a preferred choice in laboratory settings. It is soluble in organic solvents such as DMSO and acetone, which facilitates its use in a wide range of chemical reactions. The Fmoc protecting group allows for controlled deprotection under specific conditions, enabling precise chemical modifications. This controlled reactivity is crucial for the synthesis of complex molecules, including peptides and proteins. Additionally, its stability under standard laboratory conditions ensures consistent performance in experimental protocols.
In Indonesian laboratories, (Fmoc-amino)-PEG6-carboxylic Acid is commonly used in protein modification studies, drug development, and molecular interaction research. It is an essential tool for academic and industrial researchers working on biopharmaceuticals and advanced chemical synthesis. Its application spans various scientific disciplines, supporting innovation in both basic and applied research.
Laboratory Applications
Protein modification studies benefit from this compound's ability to enhance protein stability and solubility through PEGylation.
Drug development projects utilize it to improve the pharmacokinetic properties of therapeutic proteins and peptides.
Molecular interaction research leverages its reactivity to study how PEGylation affects biomolecular behavior and function.
Peptide synthesis applications take advantage of its Fmoc group for controlled deprotection during solid-phase peptide synthesis.
Biopharmaceutical research relies on its role in creating more stable and biocompatible therapeutic agents.
Specifications
Brand: TCI
CAS number: 882847-34-9
Category: Chemistry > Chemical Biology > PEGylation
Pack sizes: Available in various sizes as per supplier specifications
Physical form: Solid powder
Storage note: Store at controlled room temperature, away from moisture and light
Handling and Storage
This compound should be stored in a cool, dry place, away from direct sunlight and moisture. It is recommended to keep it in a sealed container to prevent exposure to air and humidity. Due to its reactivity, it should be handled in a well-ventilated area, preferably under a fume hood. Avoid contact with incompatible materials such as strong acids or bases. Always use appropriate personal protective equipment, including gloves and safety goggles, when handling this substance. Proper storage and handling ensure the compound remains effective and safe for use in laboratory applications.
