Hexadecafluorosebacic Acid with CAS number 307-78-8 is a ten-carbon dicarboxylic acid in which every hydrogen position along the central chain has been replaced by fluorine atoms. As a fluorinated building block, this compound provides a long perfluoroalkyl segment terminated at both ends by carboxylate groups that are ready to be reacted. In the laboratory, molecules of this type are used to introduce fluorinated character into polymers, surfaces, and coordination frameworks — that is, wherever researchers need the distinctive properties of fluorocarbons that an ordinary hydrocarbon chain simply cannot deliver.
The characteristics that make it a preferred choice follow directly from its perfluorinated chain. The carbon–fluorine bond is among the strongest in organic chemistry, so this segment confers high thermal and chemical resistance to whatever structure it is built into. The perfluoroalkyl chain is also both hydrophobic and lipophobic, which means it tends to assemble at interfaces and lower the surface energy of a material. The strong electron-withdrawing effect of the fluorine atoms increases the acidity of both carboxyl groups relative to ordinary sebacic acid, which in turn influences how strongly the molecule binds to metal centres and how it behaves in polymerisation reactions.
In Indonesian laboratories, this building block is typically found in university research groups, materials science laboratories, and industrial R&D units working on fluorinated chemistry. It is normally handled at gram scale on a synthetic bench, weighed out for reactions that build larger fluorinated structures, and stored alongside other speciality organic reagents. Supplied under the TCI brand through AMI Scientific, it serves groups that require a reliable, well-defined fluorinated diacid as a starting point rather than preparing one in-house.
- Fluorinated polymer synthesis — the two terminal carboxyl groups allow the perfluoroalkyl segment to be incorporated directly into polyester or polyamide backbones through conventional condensation chemistry.
- Surface energy modification — because the perfluoroalkyl chain is both hydrophobic and lipophobic, it migrates to interfaces and produces coatings with markedly reduced surface energy.
- Coordination framework construction — the dicarboxylate function provides two binding sites for metal centres, while the altered acidity of the fluorinated chain tunes how strongly those linkages form.
- Fluorinated linker chemistry — the molecule serves as a rigid, chemically resistant spacer when a researcher needs to separate two functional units with a thermally stable segment.
- Structure–property studies — comparison against ordinary sebacic acid lets researchers isolate exactly what perfluorination contributes to acidity, thermal stability, and interfacial behaviour in a given system.
| Brand | TCI |
|---|---|
| CAS number | 307-78-8 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Fluorinated Building Blocks |
| Pack sizes | available in standard TCI research-scale packaging; please confirm the current pack options when ordering |
| Physical form | — |
| Storage | store in a closed original container under the conditions stated on the product label |
- Chemical class: perfluorinated ten-carbon dicarboxylic acid (fluorinated building block)
Store the container tightly closed in a cool, dry, well-ventilated area away from moisture and from incompatible materials, particularly strong bases and strong oxidising agents. Keep the material in its original supplier packaging or in a chemically compatible closed container that is clearly labelled with the compound name and CAS number. As with any carboxylic acid handled in a research setting, weigh and transfer the solid inside a fume hood, wear safety glasses, nitrile gloves, and a laboratory coat, and avoid generating or inhaling dust. Return the container promptly to its designated storage location after use, and consult the manufacturer's safety data sheet before first handling and before any disposal.
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