Isocytosine TCI I0814

Isocytosine is a pyrimidine compound known as an isomer of cytosine, one of the nucleobases that make up nucleic acids. In the laboratory, this material serves as a model molecule and building block for studying the behaviour of nitrogenous bases outside the context of natural DNA and RNA. Its framework presents a combination of amino and carbonyl groups on the pyrimidine ring, allowing researchers to trace how rearranging the positions of functional groups alters patterns of molecular recognition. The product is commonly encountered in fundamental biochemistry research, medicinal chemistry, and the development of nucleoside analogues.

The characteristic that makes isocytosine a frequent choice is its ability to form hydrogen bonds with donor and acceptor patterns that differ from those of the canonical bases. This property makes it a favoured material in supramolecular chemistry, molecular self-assembly, and the design of non-natural base pairs. Its physical form is a solid that is relatively easy to weigh and handle on the milligram to gram scale, making it well suited to small-scale reactions. The stability of the pyrimidine framework also simplifies medium-term storage without complicated special handling, provided it is protected from moisture and excessive light.

In Indonesian laboratories, isocytosine is typically used in university and institutional research settings where synthetic organic chemistry, biochemistry, and materials chemistry work is carried out. It suits groups preparing nucleoside analogues, investigating hydrogen-bonding motifs, or assembling supramolecular systems on a bench scale. Because it is handled in small quantities and requires no elaborate storage infrastructure, it fits readily into the workflow of teaching laboratories and research groups alike.

• Nucleoside analogue development — the pyrimidine scaffold serves as a starting base for constructing modified nucleosides, letting chemists explore structural variations away from the canonical nucleic acid bases.
• Non-natural base pair design — its donor and acceptor arrangement differs from canonical bases, making it a direct tool for building and evaluating artificial base-pairing schemes in the laboratory.
• Supramolecular chemistry studies — the compound's hydrogen bonding capability supports the construction of ordered assemblies, allowing researchers to probe how complementary functional groups organise molecules together.
• Molecular self-assembly experiments — the combination of amino and carbonyl groups on the ring drives predictable association, giving a reliable model system for investigating spontaneous ordering of small molecules.
• Fundamental biochemistry and medicinal chemistry research — as a cytosine isomer it acts as a model compound for tracing how functional group position governs molecular recognition in biologically relevant systems.

• Product code: I0814

Store isocytosine in its original tightly closed container, kept protected from moisture and excessive light. The stability of the pyrimidine framework means medium-term storage does not demand complicated special handling, but containers should be resealed promptly after each use to limit exposure to humid air. Transfer the solid using clean, dry spatulas and weigh it into appropriate glass or chemically resistant vessels. As with any laboratory chemical, handle it in a well-ventilated area, wear standard personal protective equipment including gloves, safety glasses, and a laboratory coat, and avoid generating or inhaling dust during weighing and transfer operations.

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