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CAS 27496-82-8

Methylenedisalicylic Acid (mixture of isomers) TCI M0221

Methylenedisalicylic Acid (mixture of isomers) TCI M0221
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TCI M0221 Methylenedisalicylic Acid (mixture of isomers) is an aromatic, salicylic acid–based compound in which two rings are bridged by a methylene group, and it is supplied as a mixture of positional isomers, as is customary for condensation products of this type. In the laboratory, this material serves as a monomeric reagent and intermediate for polymer chemistry, particularly in research on phenolic resins and on materials that depend on multiple functional groups. The presence of two carboxyl groups and two phenolic hydroxyl groups within a single molecule makes it an attractive starting point for researchers who want to build polymer networks, study crosslinking reactions, or prepare more complex salicylate derivatives for further synthesis at research scale.

The characteristic that makes this material a preferred choice lies in its multifunctional structure. The carboxylate groups allow the formation of salts, esters, and amides through well-established reaction pathways, while the phenolic hydroxyl groups provide hydrogen-bonding capability and at the same time act as reactive sites toward electrophiles and activating reagents. The methylene bridge between the two rings gives a framework that is relatively rigid yet still retains some conformational freedom, so the molecule can be incorporated into a network without imposing excessive strain. Because the product is supplied as a mixture of isomers, it also reflects the realistic composition of condensation-derived materials rather than a single idealized structure.

In Indonesian laboratories, this reagent is generally used in university research groups, polymer and materials science laboratories, and institutional R&D units working on resin formulation and derivative synthesis. It is typically handled at bench scale, where small quantities are weighed out for reaction screening, crosslinking studies, or the preparation of intermediates. Researchers usually order it alongside other monomeric building blocks so that structure–property relationships can be compared systematically within a single experimental series.

  • Phenolic resin research: the combination of phenolic hydroxyl groups and a methylene bridge makes this compound directly relevant to studies of resin formation, curing behaviour, and network structure.
  • Crosslinking studies: with four reactive sites available per molecule, it functions as a multifunctional node that allows researchers to investigate network density and connectivity in polymer systems.
  • Monomer for polycondensation: the carboxyl groups participate in ester and amide-forming condensation reactions, making the material useful for preparing polyesters, polyamides, and related research polymers.
  • Synthesis of salicylate derivatives: chemists use it as a starting material to build more complex salicylic acid derivatives, exploiting the distinct reactivity of its carboxyl and phenolic functions.
  • Structure–property investigations: because it is supplied as a mixture of isomers, it is useful for examining how isomeric composition influences polymerisation behaviour and the properties of the resulting material.

Brand TCI
CAS number 27496-82-8
Molecular formula —
Purity —
Category Materials Science > Polymer/Macromolecule Reagents > Monomers
Pack sizes available in standard research and laboratory pack sizes; please confirm the currently offered packaging when ordering
Physical form —
Storage store in a tightly closed container in a cool, dry, well-ventilated place away from light
  • Product code: M0221
  • Composition: supplied as a mixture of positional isomers

Store this reagent in its original tightly closed container, kept in a cool, dry, and well-ventilated area, protected from direct sunlight and from sources of heat or ignition. Glass containers with chemically resistant closures are suitable for repackaging small working quantities, and containers should be clearly labelled with the product name and CAS number. Handle the material inside a fume hood while wearing safety goggles, chemical-resistant gloves, and a laboratory coat, and avoid generating or inhaling dust during weighing and transfer. Keep the container closed when not in use to limit moisture uptake, and always consult the manufacturer's Safety Data Sheet before use and before disposal of any residues.

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