17alpha-Methylandrostan-17beta-ol-3-one TCI M1801

TCI M1801 17alpha-Methylandrostan-17beta-ol-3-one is a synthetic steroid of the androstane class bearing a methyl group at the 17alpha position, a hydroxyl group at the 17beta position, and a ketone group at position 3. The addition of a methyl group at the quaternary carbon of position 17 is a structural modification widely recognised in steroid chemistry. In the laboratory, this compound serves as an analytical reference material, a study substance in steroid research, and a comparison standard in the development of instrumental methods that require a clear and well documented compound identity.

The most distinctive characteristic of this material is the combination of a methyl group and a hydroxyl group on a single carbon atom at position 17, which creates a fully substituted centre with considerable steric hindrance. This arrangement influences the reactivity of the hydroxyl group so that it behaves differently from steroids carrying an ordinary secondary hydroxyl, and that difference makes the compound an interesting subject in both reactivity and metabolism studies. The steroid framework is lipophilic, so the material dissolves more readily in organic solvents than in water. The ketone group at position 3 provides an additional reaction site while also contributing spectroscopic features that assist in compound identification.

In Indonesian laboratories, this compound is typically used in research and analytical settings where a well characterised steroid reference is required. It supports university and institutional research groups working on steroid chemistry, as well as analytical laboratories building and validating instrumental methods. Because the material is supplied by TCI under a defined catalogue identity, it is suited to work in which traceability of the substance used is an important part of the documentation.

• Analytical reference material: the defined catalogue identity and documented structure allow this compound to serve as a dependable comparison point in routine steroid analysis work.
• Instrumental method development: the ketone group at position 3 gives distinctive spectroscopic features, making the compound useful when establishing and refining detection and identification methods.
• Steroid reactivity studies: the fully substituted, sterically hindered carbon at position 17 provides a clear model for examining how hindrance alters the behaviour of a hydroxyl group.
• Steroid metabolism research: the 17alpha-methyl modification is a well recognised structural change in steroid chemistry, which makes the compound a relevant subject for metabolic investigation.
• Synthetic chemistry studies: the ketone at position 3 offers an additional reaction site, allowing the molecule to be used in work exploring transformations of the androstane framework.

• Chemical class: synthetic androstane steroid with 17alpha-methyl, 17beta-hydroxyl and 3-ketone groups

Store the compound in a tightly closed original container, kept in a cool, dry place away from direct sunlight, moisture, and sources of heat or ignition, and follow any storage conditions specified on the product label. Glass containers with well sealed caps are generally suitable for steroid reference materials of this type. Handle the material in a well ventilated area or fume hood, and wear appropriate personal protective equipment including gloves, safety glasses, and a laboratory coat. Avoid generating dust, avoid direct contact with skin and eyes, and keep the container closed when not in use. Prepare solutions using organic solvents suited to the lipophilic steroid framework, and dispose of residues in accordance with applicable laboratory waste procedures.

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