TCI B6529, BTP3-Neu5Ac sodium salt, is a fluorogenic substrate for detecting sialidase (neuraminidase) activity. Enzymatic cleavage of the sialic acid unit releases a fluorescent benzothiazolylphenol reporter that tends to deposit at the site of the reaction, giving sharply localised signals under a fluorescence microscope. This makes it especially suitable for histochemical imaging, cell-based assays, influenza neuraminidase studies and sialidase inhibitor screening. AMI Scientific supplies this light-sensitive reagent in original TCI packaging in a 1 mg size, for research use only.
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- Yang et al. (2024). Analysis of neuraminidase activity of human parainfluenza viruses using enzyme‐linked lectin assay and BTP3‐Neu5Ac assay. Microbiology and Immunology doi:10.1111/1348-0421.13170
- Kato et al. (2018). An easy, rapid, and sensitive method for detection of drug-resistant influenza virus by using a sialidase fluorescent imaging probe, BTP3-Neu5Ac. PLOS ONE doi:10.1371/journal.pone.0200761
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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