Cinnamonitrile (TCI C0361, CAS 1885-38-7) combines an aromatic ring, a conjugated double bond, and a nitrile group in one compact building block. The cyano group can be converted into amines, amides, carboxylic acids, or nitrogen heterocycles, giving access to a broad range of synthetic targets. As a Michael acceptor and dipolarophile, it is also valuable in conjugate additions and cycloaddition chemistry. AMI Scientific supplies this compound in a 25 g research-scale pack, and handling in a fume hood with nitrile-appropriate waste segregation is recommended.
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- Dinoiu et al. (2005). Electrochemical Partial Fluorination of Ethyl Cinnamates and Cinnamonitrile.. ChemInform doi:10.1002/chin.200537041
- GEWALD et al. (1992). ChemInform Abstract: Substituted 3‐Aminothiophenes and 3‐Aminoselenophenes from β‐Chloro‐α‐cyano‐cinnamonitrile.. ChemInform doi:10.1002/chin.199245168
- Lewis et al. (2000). Formation and Anomalous Behavior of Aminonaphthalene−Cinnamonitrile Exciplexes. The Journal of Physical Chemistry A doi:10.1021/jp9933828
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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