2-Cyanophenol (TCI C1045, CAS 611-20-1), also known as salicylonitrile, carries adjacent hydroxyl and nitrile groups on an aromatic ring. This ortho arrangement makes it a convenient precursor for benzoxazoles and other fused heterocyclic systems through intramolecular cyclization. The phenol can be etherified or acylated while the nitrile can be hydrolyzed or reduced, giving broad synthetic flexibility. AMI Scientific offers 5 g and 25 g packs; keep the solid tightly sealed and protected from light and air.
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- Conrad et al. (2010). Rotational spectra of o-, m-, and p-cyanophenol and internal rotation of p-cyanophenol. Physical Chemistry Chemical Physics doi:10.1039/c001705a
- Le Barbu-Debus et al. (2005). Localization of electronic and vibrational energy in the jet-cooledm-cyanophenol/o-cyanophenol dimer: laser induced fluorescence and fluorescence-dip IR spectra. Molecular Physics doi:10.1080/00268970500077608
- Forryan et al. (2004). Voltammetric characterisation of the radical anions of 4-nitrophenol, 2-cyanophenol and 4-cyanophenol in N,N-dimethylformamide electrogenerated at gold electrodes. Journal of Electroanalytical Chemistry doi:10.1016/j.jelechem.2003.07.001
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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