• 2-Chloropyrimidine (CAS 1722-12-9) - TCI C1050 - AMI Scientific
  • 2-Chloropyrimidine (CAS 1722-12-9) - TCI C1050 - AMI Scientific
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TCI

CAS 1722-12-9

2-Chloropyrimidine TCI C1050

2-Chloropyrimidine TCI C1050

Chemical Identity

CAS No.
1722-12-9
Formula
C4H3ClN2
Molecular weight
114.53 g/mol
Purity
>99.0%(GC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
2-chloropyrimidine
SMILES
C1=CN=C(N=C1)Cl
InChIKey
UNCQVRBWJWWJBF-UHFFFAOYSA-N
MDL
MDL00006060
PubChem
CID 74404
Rp 2.068.500,00
Rp 2.068.500,00
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2-Chloropyrimidine (TCI C1050, CAS 1722-12-9) is an electron-deficient heterocyclic building block in which the C-2 chlorine is readily displaced by nucleophiles. It provides fast access to 2-substituted pyrimidines through reaction with amines, alcohols, and thiols under mild conditions. The chlorine also serves as a handle for transition-metal-catalyzed cross-coupling, making the compound valuable for library synthesis and medicinal chemistry. AMI Scientific supplies this reagent in a 25 g pack; keep it tightly closed, dry, and away from strong bases and moisture.

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  • Maltese (1995). Relative Reactivity in Piperidino-Dechlorination of 2,4-Diamino-6-chloropyrimidine and 2,4-Diamino-6-chloropyrimidine N(3)-Oxide and Their Acetylamino Analogs. The Journal of Organic Chemistry doi:10.1021/jo00113a025
  • Żywicka et al. (2024). Cross-Section Calculations for Electron-Impact Ionization of Pyrimidine Molecule and Its Halogenated Derivatives: 2-Chloropyrimidine, 5-Chloropyrimidine, 2-Bromopyrimidine and 5-Bromopyrimidine. Molecules doi:10.3390/molecules30010006
  • Dong et al. (2019). Durable Antipilling Modification of Cotton Fabric with Chloropyrimidine Compounds. Polymers doi:10.3390/polym11101697

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.

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