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Description
TCI C1541, (R)-(-)-1-Cyclohexylethylamine (CAS 5913-13-3), is a chiral amine widely applied in asymmetric synthesis and in the classical resolution of racemic carboxylic acids. The bulky cyclohexyl ring adjacent to the stereogenic centre creates an effective chiral environment for diastereomeric salt formation and selective crystallisation. It also serves as a chiral auxiliary, a precursor to chiral ligands, and a derivatising agent for enantiomeric purity determination. Supplied by AMI Scientific in a 5 g pack, this basic liquid should be handled in a fume hood and stored tightly closed in a cool, dry place.
Scientific References
Sakai et al. (2006). Molecular mechanism of DCR phenomenon observed in (RS)-1-cyclohexylethylamine–mandelic acid resolution system. Tetrahedron: Asymmetrydoi:10.1016/j.tetasy.2006.06.037
Patel et al. (2012). Functionalization of Keggin type manganese substituted phosphotungstate by R-(−)-1-cyclohexylethylamine: Synthesis and characterization. Inorganica Chimica Actadoi:10.1016/j.ica.2011.10.017
Turani‐I‐Belloto et al. (2023). Synthesis and Characterization of (R)‐N‐1‐Cyclohexylethylamine Borane. ChemistrySelectdoi:10.1002/slct.202301646
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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