TCI C0887 Cyclopentylamine (CAS 1003-03-8) is a primary cyclic aliphatic amine that provides convenient access to the cyclopentyl fragment frequently found in bioactive molecules. Its nucleophilic amino group readily forms amides, sulfonamides, ureas, and carbamates, and participates in reductive amination and nucleophilic substitution. The compound is flammable and corrosive, so it should be handled in a fume hood with full personal protective equipment and stored away from acids and ignition sources. AMI Scientific supplies this TCI product in 25 mL and 500 mL packs for both exploratory and routine synthetic work.
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- (2007). Cyclopentylamine. Cold Spring Harbor Protocols doi:10.1101/pdb.caut2515
- Rochon et al. (2009). Multinuclear magnetic resonance studies of the reactions of the antitumor complexes cis-Pt(L)2X2 and cis-Pt(NH3)(L)X2 (L = cyclobutylamine and cyclopentylamine) with guanosine and other bases and crystal structures of Pt(cyclopentylamine)2I2. Inorganica Chimica Acta doi:10.1016/j.ica.2008.10.026
- Sundar et al. (2011). ChemInform Abstract: 1‐Phenyl‐2‐pyrrolidinyl‐cyclopentylamine via Thermal Rearrangement.. ChemInform doi:10.1002/chin.201144098
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