4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide TCI D4188

Name: TCI D4188 251456-60-7 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Brand: TCI
SKU: TCI2510D418824709
Price: 6463800.0 IDR
Availability: InStock

Rp 6.463.800,00

Sale Sold out

Shipping calculated at checkout.

Berat 20mg 100mg

Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.

Description

TCI D4188, 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, bearing CAS number 251456-60-7, is a pharmaceutical research reagent belonging to the hydroxamic acid class of compounds. Its molecular structure combines a benzamide core carrying a dimethylamino group, an aliphatic seven-carbon linker chain, and a terminal hydroxamic acid moiety capable of binding metal ions. This combination of three structural elements represents the classic architecture found in histone deacetylase enzyme inhibitor compounds that are widely used in epigenetics research. In the laboratory, this material serves as a test and comparison compound in studies of chromatin modification, gene expression, and cellular responses to pharmacological treatment, and is intended exclusively for experimental purposes.

The characteristic that makes researchers select this compound lies in its hydroxamic acid group. That group acts as a strong chelator toward metal ions at the active site of the enzyme, producing directed interactions that can be reproduced across experiments. The long methylene linker chain provides conformational flexibility so that the molecule can reach the catalytic pocket of the enzyme, while the aromatic terminus bearing the dimethylamino substituent functions as the surface-recognition element of the structure. Together, these three defined structural regions give the compound consistent and predictable behaviour in comparative assays, which is why it is chosen as a reference molecule.

In Indonesian laboratories, this reagent is typically used within university research groups, biochemistry and molecular biology laboratories, and pharmaceutical research units working on epigenetic mechanisms. It is handled by researchers examining chromatin modification and gene expression patterns, as well as by teams evaluating cellular responses to pharmacological treatment. Because the material is designated for experimental use only, it is applied strictly within controlled research settings and not in any clinical, diagnostic, or therapeutic context.

Laboratory Applications

Histone deacetylase inhibition studies — the hydroxamic acid terminus chelates metal ions at the enzyme active site, giving directed and reproducible interactions suitable for inhibition experiments.
Epigenetics research on chromatin modification — the compound's classic inhibitor architecture makes it a dependable test molecule when investigating how chromatin state is altered pharmacologically.
Gene expression profiling experiments — serves as a treatment compound for examining how modulation of chromatin modification pathways changes downstream gene expression patterns in cultured systems.
Reference and comparison compound in assay development — its three well-defined structural regions produce consistent, predictable behaviour, making it valuable as a benchmark against candidate molecules.
Cellular response evaluation under pharmacological treatment — researchers apply this reagent to observe how cells respond to compounds carrying a metal-binding hydroxamic acid pharmacophore.

Specifications

Brand: TCI (Tokyo Chemical Industry)
CAS number: 251456-60-7
Chemical name: 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Category: Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents (for Experimental Use)
Pack sizes: available in standard TCI research-scale packaging; please confirm the size required when ordering
Storage: keep in the original tightly closed container under the conditions stated on the manufacturer label and safety data sheet

Handling and Storage

Store the reagent in its original tightly closed container, protected from moisture, direct light, and heat, following the storage conditions stated on the manufacturer label and safety data sheet. Keep the material in chemically compatible glass or amber vials, and return it promptly to storage after weighing so that repeated exposure to ambient air and humidity is minimised. Handle the compound in a well-ventilated area or fume hood while wearing a laboratory coat, safety goggles, and suitable gloves, and avoid generating dust during transfer. Use clean, dry spatulas and vessels to prevent cross-contamination between experiments. As this material is intended for experimental use only, it should be handled exclusively by trained laboratory personnel, kept separate from food and beverages, and disposed of together with laboratory chemical waste in accordance with institutional procedures.