N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide TCI A2897

Chemical Identity

CAS No.: 1451042-18-4
PubChem: CID 71721946·SID 354333140
Formula: C21H19N5OS
Molecular weight: 389.5 g/mol
Purity: >95.0%(HPLC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: N-(2-aminophenyl)-4-[1-(2-thiophen-3-ylethyl)triazol-4-yl]benzamide
SMILES: C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)C3=CN(N=N3)CCC4=CSC=C4
InChIKey: LBLSLSOENGWIHL-UHFFFAOYSA-N

Rp 3.578.400,00

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Berat 5mg

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N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide is a complex chemical compound widely used in epigenetic research. It belongs to the category of molecular biology reagents and is specifically designed for studies involving histone modification. This compound plays a critical role in understanding how genetic expression is regulated through epigenetic mechanisms. Its application in laboratories is essential for investigating the molecular pathways associated with chronic diseases, including cancer and neurological disorders. Researchers rely on this compound to explore the intricate interactions between histone proteins and DNA, which are fundamental to gene regulation.

The compound's unique molecular structure allows it to interact precisely with specific biological targets, making it a preferred choice for high-precision molecular studies. Its chemical stability and good solubility enable it to be easily dissolved in various solvents, facilitating its use in analytical techniques such as spectroscopy and chromatography. These properties ensure reliable and reproducible results in laboratory experiments. Additionally, its specificity enhances the accuracy of research outcomes, making it a valuable tool in epigenetic investigations.

In Indonesian laboratories, this compound is commonly used in applied epigenetic research, particularly in studies examining the effects of histone modifications on gene expression. Researchers from universities and research institutions utilize it to explore the molecular mechanisms underlying genetic regulation. Its versatility and effectiveness make it a key reagent in advancing scientific understanding in the field of molecular biology.

Advantages (TCI brochure)

Selective HDAC3 inhibitor
Shows cell growth-inhibitory activity in human colon cancer HCT116 and prostate cancer PC-3 cell lines
Activated HIV gene expression in latent HIV-infected cells

TCI brochures (PDF)

Epigenetics Research Reagents 2024-11-22 · p. 1
Thiophenes 2026-06-29 · p. 9
Reagents for Biological Research 2025-03-11 · p. 62

Related TCI products

Epigenetic Research: This compound is ideal for studying histone modifications and their impact on gene expression, providing insights into disease mechanisms.
Drug Development: Its ability to modulate epigenetic pathways makes it useful in the development of therapeutic agents targeting chronic diseases.
Molecular Biology Studies: It supports investigations into the molecular mechanisms of gene regulation, aiding in the discovery of novel biological processes.
Chromatographic Analysis: The compound’s solubility and stability make it suitable for use in chromatographic techniques to analyze complex biological samples.
Spectroscopic Investigations: Its chemical properties allow it to be used in spectroscopic methods for identifying and characterizing molecular interactions.

From the TCI brochure

Research on HDAC3, which is highly expressed in colon and prostate cancer cells
HIV latency research using latent HIV-infected cells

Brand	TCI
CAS number	1451042-18-4
Molecular formula	—
Purity	—
Category	Life Science > Molecular Biology > Epigenetics
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Solid (as per standard chemical properties)
Storage	Store in a cool, dry place away from light

Data from the TCI brochure

Purity	>95.0%
Pack size	5mg

Source: TCI brochure LL019 (2024-11-22)

This compound should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to use airtight containers to prevent exposure to moisture and air, which could affect its stability. Since it is a chemical reagent, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Proper ventilation is essential when working with this compound to minimize inhalation risks. It is important to keep the compound away from incompatible materials to prevent any chemical reactions. Regular monitoring of storage conditions ensures the compound remains effective for research purposes.

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