TCI B6688 Biotin-PEG3-Amine (CAS 359860-27-8) is a bioconjugation reagent that pairs a biotin head group with a hydrophilic three-unit PEG spacer and a terminal primary amine. The free amine reacts readily with NHS esters and activated carboxylic acids, making it a convenient handle for biotinylating proteins, peptides, and small-molecule scaffolds. Its PEG spacer improves aqueous solubility and reduces steric crowding, allowing streptavidin to engage the biotin moiety efficiently during capture and detection. AMI Scientific supplies this reagent as a multi-vial set that helps laboratories preserve unused material between experimental runs.
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