TCI Biotin-PEG4-Azide (B5546, CAS 1309649-57-7) is a click chemistry reagent featuring a biotin affinity tag linked via a PEG4 spacer to an azide reactive group. It is primarily used for biotinylation of alkyne-modified biomolecules through copper-catalyzed or strain-promoted azide-alkyne cycloaddition reactions. This reagent is ideal for applications in protein labeling, affinity purification, pull-down assays, and various streptavidin-based detection systems.
TCI brochures (PDF)
- Bio-Orthogonal Non-Canonical Amino Acid Tagging (BONCAT) Related Reagents 2025-12-23 · p. 1
- Non-Canonical Amino Acids for Protein Site-specific Modification by Genetic Code Expansion 2024-04-16 · p. 1
- Streptavidins and Related Reagents 2025-02-28 · p. 4
- Biotinylation Reagents and Avidins 2025-06-26 · p. 2
- Bioconjugation Reagents 2026-07-07 · p. 3
- Click Chemistry 2026-09-08 · p. 8
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Product Categories
- Chemical BiologyConjugation Chemistry/Click ChemistryAzides [Conjugation Chemistry/Click Chemistry]
- Chemical BiologyConjugation Chemistry/Click ChemistryBiotin Azides/Alkynes [Conjugation Chemistry/Click Chemistry]
- Chemical BiologyConjugation Chemistry/Click ChemistryPEG Azides/Alkynes [Conjugation Chemistry/Click Chemistry]
- Chemical BiologyGlycoscienceReagents for Oligosaccharide Synthesis [Glycoscience]
- Chemical BiologyBioconjugationBiotins and Streptavidins
- GlycoscienceReagents for Oligosaccharide Synthesis [Glycoscience]
- Biochemicals and ReagentsBioconjugationBiotins and Streptavidins
- Pharmaceutical Development and Drug Discovery ResearchBioconjugationBiotins and Streptavidins
- Pharmaceutical Development and Drug Discovery ResearchConjugation Chemistry/Click ChemistryAzides [Conjugation Chemistry/Click Chemistry]
- Pharmaceutical Development and Drug Discovery ResearchConjugation Chemistry/Click ChemistryBiotin Azides/Alkynes [Conjugation Chemistry/Click Chemistry]
- Pharmaceutical Development and Drug Discovery ResearchConjugation Chemistry/Click ChemistryPEG Azides/Alkynes [Conjugation Chemistry/Click Chemistry]







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