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TCI

CAS 875770-34-6

Biotin-PEG3-Azide TCI A2523

Biotin-PEG3-Azide TCI A2523

Chemical Identity

CAS No.
875770-34-6
PubChem
CID 60146223·SID 172088926
Formula
C18H32N6O5S
Molecular weight
444.6 g/mol
Purity
>95.0%(HPLC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]pentanamide
SMILES
C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-])NC(=O)N2
InChIKey
ZWFOOMQCYIGZBE-ZOBUZTSGSA-N
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Biotin-PEG3-Azide is a chemical compound widely used in biochemical and molecular biology applications. It serves as a versatile reagent in conjugation chemistry and click chemistry, enabling the efficient and specific modification of biomolecules. This compound combines biotin, known for its high affinity to avidin, with an azide group, which is essential in click chemistry reactions. Its dual functionality makes it a key tool for researchers aiming to create bioconjugates with high specificity and stability.

The properties of Biotin-PEG3-Azide make it a preferred choice in laboratory settings. It exhibits chemical stability and high biocompatibility due to the presence of a polyethylene glycol (PEG) chain. This PEGylation reduces non-specific reactivity and enhances solubility in aqueous environments. Additionally, its ability to specifically bind to avidin or streptavidin ensures reliable and reproducible results in various experimental setups. These characteristics make it ideal for applications requiring precision and efficiency.

In Indonesian laboratories, Biotin-PEG3-Azide is commonly used in molecular biology, pharmacology, and biomedical research. It plays a crucial role in the development of biosensors, molecular conjugation, and biomolecule modification. Its reliability and effectiveness make it a staple in research focused on creating targeted and functional biomolecular systems.

  • Molecular biology research utilizes Biotin-PEG3-Azide for creating bioconjugates that enable specific molecular interactions and labeling.
  • Biosensor development benefits from this compound due to its ability to form stable and specific bonds with avidin, enhancing detection accuracy.
  • Pharmacological studies employ it for modifying drug molecules to improve targeting and reduce off-target effects through click chemistry.
  • Biomedical applications rely on its biocompatibility and specificity for designing therapeutic agents and diagnostic tools.
  • Protein engineering projects use it to attach functional groups to proteins, facilitating studies on structure, function, and interaction dynamics.

Brand TCI
CAS number 875770-34-6
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Conjugation Chemistry/Click Chemistry
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid or powder, depending on formulation
Storage Store at controlled room temperature, away from moisture and light

Biotin-PEG3-Azide should be stored in a cool, dry place, away from direct sunlight and sources of heat. It is recommended to keep the compound in a sealed container to prevent moisture absorption, which could affect its stability. When handling, it is important to use appropriate personal protective equipment, such as gloves and safety goggles, to avoid skin contact or inhalation. The compound should be stored in a well-ventilated area to ensure safe laboratory practices. Proper labeling of containers is essential for easy identification and safe handling. Always follow standard laboratory safety protocols when working with chemical reagents to maintain a secure and efficient research environment.

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