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Description
TCI B6689 Biotin-PEG4-Amine (CAS 663171-32-2) provides a biotin tag connected through a four-unit PEG spacer to a reactive terminal primary amine. The longer, highly hydrophilic spacer improves conjugate solubility in aqueous buffers and gives streptavidin better access to the biotin group. Researchers use it to biotinylate proteins, peptides, oligonucleotides, and small molecules for affinity capture, detection, and surface immobilisation work. AMI Scientific offers the reagent as a five-vial set, a format that keeps unused material sealed while individual experiments are running.
Scientific References
Liu et al. (2023). Discovery of two biotin-PEG4‑diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance. Bioorganic Chemistrydoi:10.1016/j.bioorg.2022.106323
Wang et al. (2024). Design, docking optimization, and evaluation of biotin-PEG4-1,8-naphthalimide as a potent and safe antitumor agent with dual targeting of ferroptosis and DNA. RSC Medicinal Chemistrydoi:10.1039/d4md00134f
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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