TCI C1401 DL-2-(4-Chlorophenyl)glycine (CAS 6212-33-5) is a racemic non-proteinogenic amino acid featuring a 4-chlorophenyl group on the alpha carbon. It can be protected as its Boc, Fmoc, or Cbz derivative and incorporated into peptides using standard coupling methods, where arylglycine residues modulate conformation, lipophilicity, and proteolytic stability. The racemic form is also convenient for chiral resolution studies and for validating enantioselective separation methods. AMI Scientific supplies this TCI product in 1 g, 5 g, and 25 g packs, covering everything from initial trials to preparative synthesis.
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- Fadnavis et al. (2008). Resolution of racemic 2-chlorophenyl glycine with immobilized penicillin G acylase. Tetrahedron: Asymmetry doi:10.1016/j.tetasy.2008.10.015
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