N,N-Dimethylformamide Dimethyl Acetal TCI D1293

Chemical Identity

Other names: 1,1-Dimethoxytrimethylamine
CAS No.: 4637-24-5
PubChem: CID 78373·SID 87567820
Formula: C5H13NO2
Molecular weight: 119.16 g/mol
Purity: >96.0%(GC)(T)
Reference databases: ChEBI·ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 1,1-dimethoxy-N,N-dimethylmethanamine
SMILES: CN(C)C(OC)OC
InChIKey: ZSXGLVDWWRXATF-UHFFFAOYSA-N
MDL: MDL00008482

Rp 769.650,00

~~Rp 553.350,00~~ Rp 769.650,00

Sale Sold out

Shipping calculated at checkout.

Volume 25mL 100mL 500mL

Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 2-4 minggu setelah pembayaran.

Dokumen Keamanan & Mutu

↓ Unduh SDS / MSDS (PDF resmi TCI)

CoA (Certificate of Analysis)

Spesifik per batch produksi — diterbitkan dan dikirim bersama barang sesuai nomor lot yang Anda terima.

Contoh CoA segera tersedia.

💬 Minta CoA via WhatsApp

View full details

TCI D1293 N,N-Dimethylformamide Dimethyl Acetal, commonly abbreviated as DMF-DMA, is a versatile organic synthesis reagent built on a formamide framework bearing two methoxy groups on the acetal carbon atom. It belongs to the family of non-heterocyclic building blocks and is widely recognised as a key reagent for introducing a one-carbon unit into a target molecule. In synthetic laboratories, DMF-DMA is highly valued for its ability to convert compounds containing active hydrogen into enaminones or amidines — intermediates that serve as gateways to the construction of the many heterocyclic ring systems that matter in medicinal chemistry.

The properties that make this reagent such a frequent choice are its high yet well-directed reactivity, together with the ease of using it without requiring a complicated catalyst system. DMF-DMA acts both as a source of the dimethylaminomethylene group and as a mild methylating agent for carboxylic acid functionalities, so a single reagent can serve several distinct classes of transformation. This dual capability simplifies reagent inventories and shortens route planning, since one bottle covers formylation-equivalent chemistry, amidine formation and gentle ester preparation within the same workflow.

The reagent is supplied as a liquid that is highly sensitive to moisture; contact with water hydrolyses it and reduces reaction effectiveness. For this reason, the quality of the results obtained depends strongly on moisture-free handling technique. In Indonesian laboratories this makes DMF-DMA a reagent typically reserved for synthetic and medicinal chemistry groups equipped for anhydrous work, where it is dispensed under inert conditions in university research laboratories, pharmaceutical R&D units and contract synthesis facilities carrying out heterocycle construction.

TCI brochures (PDF)

Nucleic Acid Medicine Synthesis Research Reagents 2024-11-07 · p. 2
Nucleosides, Nucleotides, Nucleic Acids and Related Reagents 2026-03-23 · p. 13
Reagents for Biological Research 2025-03-11 · p. 61

Related TCI products

Enaminone synthesis — DMF-DMA converts substrates bearing active methylene or active hydrogen centres into enaminones cleanly, giving reliable access to versatile intermediates without complicated catalyst systems.
Heterocyclic ring construction — the enaminone and amidine intermediates generated by this reagent act as direct precursors to the many heterocyclic scaffolds required throughout medicinal chemistry programmes.
Amidine formation — the reagent transfers its dimethylaminomethylene unit to suitable nitrogen-containing substrates, delivering amidine products through a single, well-directed and readily controlled transformation step.
One-carbon unit introduction — DMF-DMA serves as a dependable source of a single carbon atom for building block elaboration, extending molecular frameworks in non-heterocyclic building block chemistry.
Mild esterification of carboxylic acids — acting as a gentle methylating agent, the reagent converts carboxylic acid groups without the harsh conditions that more aggressive methylating reagents demand.

Brand	TCI
CAS number	4637-24-5
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	available in the standard TCI catalogue pack sizes for this item
Physical form	liquid
Storage	highly moisture sensitive; store under strictly anhydrous conditions

Product code: D1293

Store the reagent in its original tightly sealed container, kept in a cool, dry and well-ventilated area away from sources of ignition and from any incompatible materials. Because DMF-DMA hydrolyses on contact with water, the container should be protected from atmospheric moisture at all times; an inert gas blanket and a desiccated storage cabinet are appropriate. Dispense using dry glassware and dry syringe or cannula technique, and reseal immediately after use to limit air ingress. Handle inside a functioning fume hood while wearing safety glasses, chemically resistant gloves and a laboratory coat. Consult the manufacturer's safety data sheet before first use and follow institutional waste disposal procedures.

—