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Description
Dibenzocyclooctyne-S-S-PEG3-Biotin is a chemical compound widely utilized in chemical biology, particularly in conjugation chemistry and click chemistry applications. This compound serves as a key reagent in laboratories for facilitating rapid and specific molecular interactions. Its unique structure enables it to act as a molecular linker, connecting biotin molecules through a disulfide bond, making it highly versatile for various biochemical applications. In research settings, it plays a crucial role in the development of bioconjugates, diagnostic tools, and therapeutic agents.
One of the main reasons for its popularity is its ability to form highly specific interactions with biotin-binding proteins such as avidin and streptavidin. This specificity ensures reliable and efficient conjugation processes, which are essential in many advanced research projects. Additionally, the PEG3 segment provides hydrophilic properties, enhancing the compound’s solubility and stability in different experimental conditions. These characteristics make it a preferred choice for scientists working in complex biochemical environments.
In Indonesian laboratories, Dibenzocyclooctyne-S-S-PEG3-Biotin is commonly used in biomedical, pharmacological, and biotechnology research. Its role in enabling precise molecular conjugation supports the development of innovative diagnostic and therapeutic solutions. Researchers rely on this compound for its reliability, efficiency, and compatibility with a wide range of experimental protocols. Its application is particularly relevant in studies involving protein labeling, antibody conjugation, and nanoparticle functionalization.
Laboratory Applications
Bioconjugation Applications: This compound is ideal for bioconjugation due to its ability to link biotin to various biomolecules, enabling targeted labeling and functionalization of proteins, antibodies, and nanoparticles.
Diagnostic Reagent Development: It is widely used in the development of diagnostic tools, where precise molecular interactions are essential for detecting biomarkers and disease indicators.
Nanoparticle Functionalization: Its hydrophilic PEG3 chain enhances the stability and solubility of nanoparticles, making it suitable for surface modification and targeted drug delivery systems.
Protein Labeling Studies: The compound facilitates the efficient labeling of proteins with biotin, supporting research in structural biology and molecular imaging.
Immunological Research: It is used in immunological studies to conjugate antibodies with biotin, aiding in the development of immunoassays and biosensors.
Specifications
Brand: TCI
CAS number: 1430408-09-5
Category: Chemistry > Chemical Biology > Conjugation Chemistry/Click Chemistry
Pack sizes: Available in various quantities as per supplier specifications
Physical form: Solid powder
Storage note: Store at controlled room temperature, away from moisture and light
Handling and Storage
This compound should be stored in a dry, cool environment, away from direct sunlight and sources of heat. It is recommended to use airtight containers to prevent exposure to moisture, which can affect its stability. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Proper ventilation is also advised when working with this material to minimize inhalation risks. It is important to keep the compound in a secure location, away from incompatible substances, to maintain its integrity and ensure safe laboratory practices.
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