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Description
The TCI D5939 144089-97-4 DMT-2'-Fluoro-dG(Ib) Phosphoramidite is a chemical compound used in nucleic acid synthesis, particularly in the production of oligonucleotides. This phosphoramidite is a key reagent in the synthesis of DNA and RNA molecules, playing a critical role in molecular biology research. It is widely utilized in biomedicine and biotechnology for constructing nucleic acid molecules with specific structures. In laboratory settings, this compound serves as a fundamental building block for creating DNA or RNA probes, which are essential for genetic analysis and disease diagnosis.
This phosphoramidite is preferred due to its chemical stability and compatibility with complex chemical reactions, such as phosphoramidite coupling reactions. Its designed structure ensures efficient and accurate synthesis of nucleotides, making it a reliable choice for high-precision applications. The compound's ability to participate in controlled chemical processes without degrading or causing side reactions enhances its utility in laboratory workflows. Its consistent performance and predictable behavior make it a trusted reagent in nucleic acid chemistry.
In Indonesian laboratories, this compound is commonly used in genetic research, molecular diagnostics, and biomedical technology development. Research institutions and universities in Indonesia rely on it to expand knowledge about nucleic acid structures and functions. Its application in diagnostic tools and genetic studies supports advancements in both academic and applied research fields.
Laboratory Applications
Genetic research utilizes this phosphoramidite for constructing DNA probes that enable the detection of specific genetic sequences, aiding in mutation analysis and gene expression studies.
Molecular diagnostics benefits from this compound as it is essential in synthesizing oligonucleotide probes used in PCR and hybridization techniques for disease detection and genetic testing.
Biomedical technology development incorporates this reagent to design nucleic acid-based therapeutics and diagnostic tools, supporting innovation in healthcare solutions.
DNA sequencing applications rely on this phosphoramidite for synthesizing high-quality oligonucleotides that are critical in next-generation sequencing workflows.
RNA synthesis projects use this compound to produce RNA molecules with precise sequences, facilitating studies on gene regulation and RNA-based therapeutics.
Specifications
Brand: TCI
CAS number: 144089-97-4
Category: Chemistry > Chemical Biology > Nucleic Acid Chemistry
Pack sizes: Not specified
Physical form: Not specified
Storage note: Store in a cool, dry place away from light and moisture
Handling and Storage
This phosphoramidite should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Proper ventilation should be ensured in the storage area to minimize the risk of chemical fumes. Laboratory personnel should handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. It is important to keep the compound away from incompatible substances to avoid any potential chemical reactions. Regular inspection of storage conditions ensures the compound remains in optimal condition for use in nucleic acid synthesis applications.
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