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Description
DMT-2'-Fluoro-dU Phosphoramidite is a chemical compound used in the synthesis of DNA and RNA, particularly in phosphoramidite chemistry. This compound plays a crucial role in the creation of oligonucleotides, which are essential for various biochemical experiments. In laboratory settings, it is widely utilized to construct DNA or RNA molecules with specific modifications, such as nucleotide substitutions, to enhance molecular stability and functional specificity. Its application is vital in research areas that require precise molecular design and manipulation.
The compound is known for its stable chemical structure and controlled reactivity, which allows for accurate and efficient synthesis processes. It dissolves well in organic solvents, making it suitable for use in synthesis reactors. These properties contribute to its reliability in high-precision experiments, ensuring consistent results. Its compatibility with standard synthesis protocols further enhances its appeal among researchers.
In Indonesian laboratories, DMT-2'-Fluoro-dU Phosphoramidite is commonly used in genetic research, biotechnology, and pharmacology. Researchers in educational and research institutions rely on this compound to produce oligonucleotides for gene function studies, molecular biology experiments, and drug development. Its versatility and performance make it a preferred choice for advanced biochemical applications.
Laboratory Applications
Genetic Research: This compound is ideal for gene function studies as it enables the synthesis of modified oligonucleotides for DNA and RNA analysis.
Biotecnology: It supports the development of molecular tools for genetic engineering and synthetic biology applications.
Pharmacology: It is used in drug discovery to create nucleic acid-based therapeutics and probe molecules.
Molecular Biology: Its role in DNA and RNA synthesis makes it essential for experiments involving gene expression and regulation.
Diagnostic Development: It aids in the creation of nucleic acid probes for diagnostic assays and genetic testing.
Specifications
Brand: TCI
CAS number: 146954-75-8
Category: Chemistry > Chemical Biology > Nucleic Acid Chemistry
Pack sizes: Available in standard laboratory quantities
Physical form: Solid or powder, depending on formulation
Storage note: Store in a cool, dry place away from light
Handling and Storage
This compound should be stored in a cool, dry place away from direct light to maintain its stability and reactivity. It is recommended to use airtight containers to prevent moisture absorption and contamination. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Proper labeling of containers is essential for safe handling and to prevent accidental exposure. The compound should not be stored near incompatible materials or sources of heat. Regular inspection of storage conditions is advised to ensure optimal preservation and usability.
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