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Description
DMT-5-Me-dC(Bz) Phosphoramidite is a chemical compound used in the synthesis of nucleic acids such as DNA and RNA. It serves as a key component in the production of oligonucleotides, which are essential in biomedical research, genetics, and biotechnology. In laboratory settings, this compound functions as a precursor for constructing nucleotide chains required for various applications, including synthetic DNA production, sequencing testing, and genetic modification. Its role is critical in enabling precise and efficient nucleic acid synthesis.
This phosphoramidite is preferred due to its stable chemical structure and appropriate reactivity for laboratory chemical reactions. It exhibits chemical properties that allow it to react specifically with other reagents during synthesis processes. The compound’s ability to participate in phosphodiester bond formation is central to the synthesis of nucleic acids. These characteristics make it a reliable and efficient tool for researchers working with nucleic acid chemistry.
In Indonesian laboratories, DMT-5-Me-dC(Bz) Phosphoramidite is commonly used by researchers in molecular biology, genetics, and pharmacology. It plays a vital role in studies involving genetic modification, DNA synthesis, and drug development. Its availability supports ongoing research and innovation in these fields, making it an essential material for scientific advancement.
Laboratory Applications
Genetic modification studies benefit from this phosphoramidite as it enables precise synthesis of modified nucleotides for gene editing applications.
DNA synthesis projects rely on this compound to construct custom oligonucleotides for cloning, hybridization, and sequencing experiments.
Biotransformation research uses this material to create modified nucleotides for studying enzyme activity and metabolic pathways.
Molecular biology experiments require this phosphoramidite to produce specific DNA sequences for PCR, hybridization, and probe design.
Drug development initiatives utilize this compound to synthesize nucleotide-based therapeutics and study their interaction with biological systems.
Specifications
Brand: TCI
CAS number: 105931-57-5
Category: Chemistry > Chemical Biology > Nucleic Acid Chemistry
Pack sizes: Not specified
Physical form: Not specified
Storage note: Store in a cool, dry place away from moisture and light
Handling and Storage
This phosphoramidite should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep it in a sealed container to prevent exposure to moisture and air. Proper ventilation is necessary when handling the compound to ensure safe laboratory conditions. Avoid direct contact with skin and eyes, and use appropriate personal protective equipment. The compound should be handled in a fume hood to minimize exposure during synthesis procedures. Regular monitoring of storage conditions ensures the material remains effective for its intended applications.
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