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Description
The TCI D6080 163496-23-9 DMT-2'-O-TBDMS-pseudouridine Phosphoramidite is a specialized chemical compound used in nucleic acid synthesis and related biochemical applications. It plays a critical role in the preparation of modified oligonucleotides, which are essential in molecular biology research. This phosphoramidite is widely utilized in the development of RNA and DNA sequences with specific structural modifications, making it a key reagent in advanced genetic and biotechnological studies. Its unique chemical structure enables it to be incorporated into nucleotide chains during synthesis, offering precise control over the final product.
This compound is preferred due to its stability and reactivity under controlled laboratory conditions. Its phosphoramidite form allows for efficient coupling during solid-phase synthesis, ensuring high yield and purity in the final oligonucleotide products. The molecule’s design also facilitates the introduction of pseudouridine, a modified nucleoside known for its functional importance in RNA structures. These properties make it a reliable and versatile reagent for researchers working on nucleic acid chemistry and related fields.
In Indonesian laboratories, this product is highly relevant for biotechnology and biochemical research. It is commonly used in the synthesis of modified RNA and DNA sequences, supporting advancements in genetic engineering and molecular diagnostics. Many research institutions and universities in Indonesia rely on this compound for developing innovative techniques in nucleic acid synthesis, which are crucial for both academic and industrial applications.
Laboratory Applications
RNA and DNA Modification Synthesis: This phosphoramidite is ideal for creating modified nucleic acids, enabling the study of RNA structures and functions in biological systems.
Oligonucleotide Development: Its use in oligonucleotide synthesis supports the creation of custom DNA and RNA sequences for various research and diagnostic applications.
Genetic Engineering Research: The compound facilitates the production of modified nucleotides, which are essential in gene editing and synthetic biology projects.
Molecular Diagnostics: It is used in the development of diagnostic tools that require precise nucleic acid sequences for accurate detection and analysis.
Biotechnology Innovation: Indonesian laboratories leverage this product to advance biotechnological applications, including therapeutic RNA development and biomarker research.
Specifications
Brand: TCI
CAS number: 163496-23-9
Category: Chemistry > Chemical Biology > Nucleic Acid Chemistry
Pack sizes: Not specified
Physical form: Not specified
Storage note: Store in a cool, dry place away from light
Handling and Storage
This phosphoramidite should be stored in a cool, dry environment, away from direct light and moisture. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its chemical nature, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. Proper ventilation is essential when working with this compound to minimize inhalation risks. The material is sensitive to degradation, so maintaining optimal storage conditions is crucial to ensure its integrity and effectiveness in laboratory applications. Always follow standard laboratory safety protocols when handling and storing this reagent.
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