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    TCI

    65031-96-1 (S)-Glycidyl Butyrate TCI G0283

    65031-96-1 (S)-Glycidyl Butyrate TCI G0283
    Rp 827.400,00
    Rp 827.400,00
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    (S)-Glycidyl Butyrate is the enantiomer of the (R) form and exists as the butyrate ester of glycidol with the (S) configuration. In the laboratory, this compound serves as a chiral starting material that supplies a three-carbon framework together with two functional groups of differing reactivity, namely the epoxide ring and the ester group. With these features in hand, researchers can design controlled reaction sequences toward target molecules whose activity depends heavily on spatial configuration, without having to go through time-consuming racemate resolution steps.

    The property that makes it a frequent choice is the dual role of the butyrate group, acting as a temporary protecting group for the primary hydroxyl while at the same time improving solubility in organic solvents. This pattern allows nucleophiles to be directed first toward the oxirane ring, after which the ester group can be opened through hydrolysis, alcoholysis, or an enzymatic reaction. The compound generally appears as a colorless to pale yellow liquid, is easily transferred by syringe, and suits small-scale work as well as reactions under air-free conditions that demand accurate and repeatable volume measurement during optimization.

    In Indonesian laboratories, compounds of this class attract interest from research groups working on asymmetric synthesis, medicinal chemistry, and the preparation of chiral building blocks. The liquid form makes it practical for bench-scale work where reagents are dispensed by syringe in modest quantities, and the defined stereochemistry removes the need for separate resolution work, which is valuable where instrument time and separation capacity are shared across several projects.

    • Asymmetric synthesis of chiral intermediates, where the defined (S) configuration lets researchers carry stereochemical information forward into the target molecule without a separate resolution stage.
    • Regioselective epoxide ring-opening studies, since the oxirane can be attacked by nucleophiles first while the butyrate ester remains intact as a temporary protecting group.
    • Preparation of three-carbon chiral building blocks, because the compound supplies a short framework bearing two functional groups with clearly different reactivity profiles.
    • Enzymatic and chemoenzymatic deprotection work, as the butyrate ester can be cleaved through enzymatic reaction, hydrolysis, or alcoholysis after the epoxide has been transformed.
    • Small-scale air-free reaction optimization, where the colorless to pale yellow liquid form allows accurate, repeatable syringe transfer across successive screening experiments.

    Brand TCI
    CAS number 65031-96-1
    Molecular formula —
    Purity —
    Category TCI
    Pack sizes Available in TCI standard packaging; please refer to the product listing for the sizes currently offered
    Physical form Colorless to pale yellow liquid
    Storage Store in a tightly closed container in a cool, dry place away from direct sunlight
    • Product Name: (S)-Glycidyl Butyrate (TCI G0283)

    Store the container tightly closed in a cool, dry, and well-ventilated area, protected from direct sunlight and sources of heat or ignition. Original manufacturer bottles are the most suitable containers; where material is transferred, use clean, dry, chemically compatible glassware with a secure closure, and keep septum-sealed vials for portions dispensed by syringe under air-free conditions. Handle the compound in a fume hood using safety glasses, gloves, and a laboratory coat, and avoid contact with skin, eyes, and clothing. Because the epoxide ring is reactive, keep the material away from strong nucleophiles, acids, bases, and oxidizing agents, close the container promptly after use, label transferred portions clearly, and consult the manufacturer's safety data sheet before use and disposal.

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