TCI D1329 1,2-Diaminopropane-N,N,N',N'-tetraacetic Acid is an aminopolycarboxylate chelating agent whose structure closely resembles that of EDTA, differing only in that the ethylenediamine backbone is replaced by 1,2-diaminopropane, which carries one additional methyl group. The compound offers six coordination points — two amine nitrogen atoms and four carboxylate groups — allowing it to bind both divalent and trivalent metal ions to form tight, stable chelate complexes. In the laboratory, its role is to mask or solubilise metal ions, whether for analytical purposes, for controlling reaction interference, or for preparing stable metal solutions.
The advantage that leads laboratories to select it over conventional chelating agents lies in the methyl group on its main chain. That small substituent alters the rigidity of the framework and the crystal packing pattern of the complexes that form, which in practice often yields metal chelate salts with better solubility and a lower tendency to precipitate over certain pH ranges. This property is valuable whenever a working solution must remain clear for an extended period. The compound is supplied as a solid powder that is easy to weigh out, and the free acid form serves as the starting point for preparing the corresponding salt solutions.
In Indonesian laboratories, this reagent fits naturally into everyday analytical and synthetic routines where metal ions must be held in solution or kept from interfering with a measurement. It is used in academic research laboratories, in university teaching and research facilities, and in industrial quality-control settings that prepare their own metal standards and working solutions. Because it is weighed directly as a powder, it suits laboratories that formulate chelate solutions in-house rather than purchasing them ready-made.
- Metal ion masking in analytical procedures — the six coordination sites bind interfering divalent and trivalent metal ions tightly, removing their influence on the measurement being carried out.
- Preparation of stable metal working solutions — the chelate complexes formed resist precipitation, so solutions of defined metal content stay clear and usable across an extended working period.
- Complexometric and chelation chemistry studies — as a close structural analogue of EDTA with one extra methyl group, it serves comparative work on how backbone substitution affects complex stability.
- Control of reaction interference in synthetic chemistry — trace metal ions that would otherwise disturb a reaction can be sequestered, keeping the intended synthetic pathway free from unwanted catalysis.
- Solubilisation of metal species in aqueous systems — the improved solubility of its metal chelate salts helps keep metals dissolved where conventional chelating agents tend to form precipitates.
| Brand | TCI |
|---|---|
| CAS number | 4408-81-5 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Synthetic Reagents > Chelation/Complexation Compounds |
| Pack sizes | available in standard TCI catalogue packaging; please confirm the pack size required when ordering |
| Physical form | solid powder, easily weighed; supplied as the free acid form |
| Storage | keep in a closed container in a dry place, away from moisture |
Store the product in its original tightly closed container in a cool, dry, well-ventilated area, protected from moisture that could cause the powder to cake and complicate accurate weighing. Glass or chemically resistant plastic containers with secure closures are appropriate for any portions transferred out of the original packaging, and each should be clearly labelled. Handle the powder in a fume hood or a well-ventilated workspace, wearing gloves, safety goggles, and a laboratory coat to avoid contact with skin and eyes and to limit dust inhalation. Use clean, dry spatulas when weighing to prevent contamination of the bulk material, and close the container promptly after use. Follow the safety data sheet supplied with the product and your institution's standard chemical handling procedures.
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